作者:Mosharov, Eugene V.; Rosenberg, Ayelet M.; Monzel, Anna S.; Osto, Corey A.; Stiles, Linsey; Rosoklija, Gorazd B.; Dwork, Andrew J.; Bindra, Snehal; Junker, Alex; Zhang, Ya; Fujita, Masashi; Mariani, Madeline B.; Bakalian, Mihran; Sulzer, David; De Jager, Philip L.; Menon, Vilas; Shirihai, Orian S.; Mann, J. John; Underwood, Mark D.; Boldrini, Maura; de Schotten, Michel Thiebaut; Picard, Martin
作者:Shao, Ling-Xiao; Liao, Clara; Davoudian, Pasha A.; Savalia, Neil K.; Jiang, Quan; Wojtasiewicz, Cassandra; Tan, Diran; Nothnagel, Jack D.; Liu, Rong-Jian; Woodburn, Samuel C.; Bilash, Olesia M.; Kim, Hail; Che, Alicia; Kwan, Alex C.
作者单位:Cornell University; Yale University; Yale University; Yale University; Korea Advanced Institute of Science & Technology (KAIST); Cornell University; Weill Cornell Medicine
摘要:Psilocybin is a serotonergic psychedelic with therapeutic potential for treating mental illnesses1, 2, 3-4. At the cellular level, psychedelics induce structural neural plasticity5,6, exemplified by the drug-evoked growth and remodelling of dendritic spines in cortical pyramidal cells7, 8-9. A key question is how these cellular modifications map onto cell-type-specific circuits to produce the psychedelics' behavioural actions10. Here we use in vivo optical imaging, chemogenetic perturbation an...
作者:Wen, Chengqian; Xu, Xintao; Guo, Huiping
作者单位:Qingdao University of Technology