8069期

最新文章

• Traceable random numbers from a non-local quantum advantage AI翻译
  作者：Kavuri, Gautam A.; Palfree, Jasper; Reddy, Dileep V.; Zhang, Yanbao; Bienfang, Joshua C.; Mazurek, Michael D.; Alhejji, Mohammad A.; Siddiqui, Aliza U.; Cavanagh, Joseph M.; Dalal, Aagam; Abellan, Carlos; Amaya, Waldimar; Mitchell, Morgan W.; Stange, Katherine E.; Beale, Paul D.; Brandao, Luis T. A. N.; Booth, Harold; Peralta, Rene; Nam, Sae Woo; Mirin, Richard P.; Stevens, Martin J.; Knill, Emanuel; Shalm, Lynden K.
  作者单位：University of Colorado System; University of Colorado Boulder; National Institute of Standards & Technology (NIST) - USA; United States Department of Energy (DOE); Oak Ridge National Laboratory; University System of Maryland; University of Maryland College Park; National Institute of Standards & Technology (NIST) - USA; University of New Mexico; University of Colorado System; University of Colorado Boulder; Barcelona Institute of Science & Technology; Universitat Politecnica de Catalunya; Institut de Ciencies Fotoniques (ICFO); ICREA; University of Colorado System; University of Colorado Boulder; National Institute of Standards & Technology (NIST) - USA; University of Colorado System; University of Colorado Boulder; National Institute of Standards & Technology (NIST) - USA; University of Colorado System; University of Colorado Boulder; University of California System; University of California Berkeley
  摘要：The unpredictability of random numbers is fundamental to both digital security1,2 and applications that fairly distribute resources3,4. However, existing random number generators have limitations-the generation processes cannot be fully traced, audited and certified to be unpredictable. The algorithmic steps used in pseudorandom number generators5 are auditable, but they cannot guarantee that their outputs were a priori unpredictable given knowledge of the initial seed. Device-independent quan...
• Why China's innovation model is thriving AI翻译
  作者：Dreyer, Jacob
• An aspirational approach to planetary futures AI翻译
  作者：Ellis, Erle C.; Malhi, Yadvinder; Ritchie, Hannah; Montana, Jasper; Diaz, Sandra; Obura, David; Clayton, Susan; Leach, Melissa; Pereira, Laura; Marris, Emma; Muthukrishna, Michael; Fu, Bojie; Frankopan, Peter; Grace, Molly K.; Barzin, Samira; Watene, Krushil; Depsky, Nicholas; Pasanen, Josefin; Conceicao, Pedro
  作者单位：University System of Maryland; University of Maryland Baltimore County; University of Oxford; University of Oxford; University of Oxford; Australian National University; Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET); National University of Cordoba; University System of Ohio; College of Wooster; University of Cambridge; University of Cambridge; University of Witwatersrand; Stockholm University; University of London; London School Economics & Political Science; University of London; London School Economics & Political Science; Chinese Academy of Sciences; Research Center for Eco-Environmental Sciences (RCEES), CAS; University of Oxford; University of Oxford; University of Auckland
  摘要：Prevailing frameworks to address planetary environmental challenges tend to focus on setting goals, targets, or boundaries to limit human harm to ecosystems or species. Here we propose an aspirational approach aimed at empowering people to shape a better future for all of life on Earth. We do this by building on the human development approach and its supporting metrics, especially the Human Development Index (HDI), a broadly influential framework that has contributed to decades of human progre...
• Y-chromosome loss in cancer and immune cells might worsen treatment outcomes AI翻译
  作者：McGranahan, Nicholas; Roychoudhuri, Rahul
  作者单位：University of London; University College London; University of Cambridge
  摘要：Prognosis is poor for tumours with Y-chromosome loss. Examining the interplay between cancer and immune cells sheds light on potential mechanisms.
• Divergent DNA methylation dynamics in marsupial and eutherian embryos AI翻译
  作者：Leeke, Bryony J.; Varsally, Wazeer; Ogushi, Sugako; Zohren, Jasmin; Menchero, Sergio; Courtois, Aurelien; Snell, Daniel M.; Teissandier, Aurelie; Ojarikre, Obah; Mahadevaiah, Shantha K.; Decarpentrie, Fanny; Oakey, Rebecca J.; VandeBerg, John L.; Turner, James M. A.
  作者单位：Francis Crick Institute; Imperial College London; Francis Crick Institute; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Universite PSL; UNICANCER; Institut Curie; Institut National de la Sante et de la Recherche Medicale (Inserm); Novartis; University of London; King's College London; University of Texas System; University of Texas Rio Grande Valley; University of Texas System; University of Texas Rio Grande Valley
  摘要：Based on seminal work in placental species (eutherians)1, 2, 3, 4, 5, 6, 7, 8, 9-10, a paradigm of mammalian development has emerged wherein the genome-wide erasure of parental DNA methylation is required for embryogenesis. Whether such DNA methylation reprogramming is, in fact, conserved in other mammals is unknown. Here, to resolve this point, we generated base-resolution DNA methylation maps in gametes, embryos and adult tissues of a marsupial, the opossum Monodelphis domestica, revealing v...
• Ice society: looking for life at unlikely altitudes AI翻译
  作者：Bradley, James; Crow, James Mitchell
  作者单位：Aix-Marseille Universite
• A soft-clamped topological waveguide for phonons AI翻译
  作者：Xi, Xiang; Chernobrovkin, Ilia; Kosata, Jan; Kristensen, Mads B.; Langman, Eric; Sorensen, Anders S.; Zilberberg, Oded; Schliesser, Albert
  作者单位：University of Copenhagen; Niels Bohr Institute; University of Copenhagen; Niels Bohr Institute; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Konstanz
  摘要：Topological insulators were originally discovered for electron waves in condensed-matter systems. Recently, this concept has been transferred to bosonic systems such as photons1 and phonons2, which propagate in materials patterned with artificial lattices that emulate spin-Hall physics. This work has been motivated, in part, by the prospect of topologically protected transport along edge channels in on-chip circuits2,3. In principle, topology protects propagation against backscattering, but no...
• Origins of the 'vampire fungus' that causes white-nose syndrome in bats AI翻译
  作者：Fisher, Matthew C.
  作者单位：Imperial College London
  摘要：An emerging fungal infection is endangering bats in America. DNA analysis reveals that the infection first arose in Europe, mediated by two fungal culprits.
• Chromatin loops are an ancestral hallmark of the animal regulatory genome AI翻译
  作者：Kim, Iana V.; Navarrete, Cristina; Grau-Bove, Xavier; Iglesias, Marta; Elek, Anamaria; Zolotarov, Grygoriy; Bykov, Nikolai S.; Montgomery, Sean A.; Ksiezopolska, Ewa; Canas-Armenteros, Didac; Soto-Angel, Joan J.; Leys, Sally P.; Burkhardt, Pawel; Suga, Hiroshi; de Mendoza, Alex; Marti-Renom, Marc A.; Sebe-Pedros, Arnau
  作者单位：Barcelona Institute of Science & Technology; Pompeu Fabra University; Centre de Regulacio Genomica (CRG); Pompeu Fabra University; University of Bergen; University of Alberta; Prefectural University of Hiroshima; University of London; Queen Mary University London; ICREA; Wellcome Trust Sanger Institute
  摘要：In bilaterian animals, gene regulation is shaped by a combination of linear and spatial regulatory information. Regulatory elements along the genome are integrated into gene regulatory landscapes through chromatin compartmentalization1,2, insulation of neighbouring genomic regions3,4 and chromatin looping that brings together distal cis-regulatory sequences5. However, the evolution of these regulatory features is unknown because the three-dimensional genome architecture of most animal lineages...
• Missile defence won't prevent the health crises that rock global security AI翻译
  作者：Evaborhene, Nelson
  作者单位：University of Witwatersrand