作者：Snyder, Joel S.; Cheng, Tony; Klincewicz, Michal; Schmitz, Michael; Sebastian, Miguel Angel
作者单位：Nevada System of Higher Education (NSHE); University of Nevada Las Vegas; Waseda University; Tilburg University; University of Vienna; Universidad Nacional Autonoma de Mexico
作者：Okonechnikov, Konstantin; Joshi, Piyush; Koerber, Verena; Rademacher, Anne; Bortolomeazzi, Michele; Mallm, Jan-Philipp; Vaillant, Jan; da Silva, Patricia Benites Goncalves; Statz, Britta; Sepp, Mari; Sarropoulos, Ioannis; Yamada, Tetsuya; Wittmann, Andrea; Schramm, Kathrin; Blattner-Johnson, Mirjam; Fiesel, Petra; Jones, Barbara; Jaeger, Natalie; Milde, Till; Pajtler, Kristian W.; van Tilburg, Cornelis M.; Witt, Olaf; Bochennek, Konrad; Weber, Katharina Johanna; Nonnenmacher, Lisa; Reimann, Christian; Ghasemi, David R.; Schueller, Ulrich; Mynarek, Martin; Rutkowski, Stefan; Jones, David T. W.; Korshunov, Andrey; Rippe, Karsten; Westermann, Frank; Thongjuea, Supat; Hoefer, Thomas; Kaessmann, Henrik; Kutscher, Lena M.; Pfister, Stefan M.
作者单位：Helmholtz Association; German Cancer Research Center (DKFZ); Ruprecht Karls University Heidelberg; National Center for Tumor Diseases; Helmholtz Association; German Cancer Research Center (DKFZ); Helmholtz Association; German Cancer Research Center (DKFZ); Helmholtz Association; German Cancer Research Center (DKFZ); Helmholtz Association; German Cancer Research Center (DKFZ); University of Oxford; Helmholtz Association; German Cancer Research Center (DKFZ); Ruprecht Karls University Heidelberg; Helmholtz Association; German Cancer Research Center (DKFZ); Helmholtz Association; German Cancer Research Center (DKFZ); Ruprecht Karls University Heidelberg; Ruprecht Karls University Heidelberg; Helmholtz Association; German Cancer Research Center (DKFZ); Helmholtz Association; German Cancer Research Center (DKFZ); Ruprecht Karls University Heidelberg; Helmholtz Association; German Cancer Research Center (DKFZ); Goethe University Frankfurt; Goethe University Frankfurt Hospital; Goethe University Frankfurt; Goethe University Frankfurt Hospital; Helmholtz Association; German Cancer Research Center (DKFZ); Goethe University Frankfurt; Goethe University Frankfurt Hospital; Ulm University; University of Hamburg; University Medical Center Hamburg-Eppendorf; University of Hamburg; University Medical Center Hamburg-Eppendorf; University of Hamburg; University Medical Center Hamburg-Eppendorf; Ruprecht Karls University Heidelberg; Helmholtz Association; German Cancer Research Center (DKFZ)
摘要：Despite recent advances in understanding disease biology, treatment of group 3/4 medulloblastoma remains a therapeutic challenge in paediatric neuro-oncology1. Bulk-omics approaches have identified considerable intertumoural heterogeneity in group 3/4 medulloblastoma, including the presence of clear single-gene oncogenic drivers in only a subset of cases, whereas in most cases, large-scale copy number aberrations prevail2,3. However, intratumoural heterogeneity, the role of oncogene aberration...
作者：Ghosh, Bikash; Labendik, Maria; Umansky, Vladimir; Heiblum, Moty; Mross, David F.
作者单位：Weizmann Institute of Science; Weizmann Institute of Science
摘要：Aharonov-Bohm interference of fractional quasiparticles in the quantum Hall effect generally reveals their elementary charge (e*)1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14-15. Recently, our interferometry experiments with several 'particle states' reported flux periods of Delta Phi = (e/e*)Phi 0 (with Phi 0 the flux quantum) at moderate temperatures16. Here we report interference measurements of 'particle-hole conjugated' states at filling factors nu = 2/3, 3/5 and 4/7, which revealed unexp...
作者：Jeong, Nuri; Zheng, Xiao; Paulson, Abigail L.; Prince, Stephanie M.; Nguyen, Victor P.; Thomas, Sherina R.; Gilpin, Caroline E.; Goodson, Matthew C.; Singer, Annabelle C.
作者单位：University System of Georgia; Georgia Institute of Technology; Emory University; Emory University; University System of Georgia; Georgia Institute of Technology
摘要：Goal-directed navigation in a new environment requires quickly identifying and exploiting important locations. Identifying new goal locations depends on neural computations that rapidly represent locations and connect location information to key outcomes such as food1. However, the mechanisms to trigger these computations at behaviourally relevant locations are not well understood. Here we show that parvalbumin (PV)-positive interneurons in the mouse hippocampal CA3 have a causal role in ident...
