Y-chromosome loss in cancer and immune cells might worsen treatment outcomes

• 成果类型: News Item
• 署名作者: McGranahan, Nicholas; Roychoudhuri, Rahul
• 署名单位: University of London; University College London; University of Cambridge
• 刊物名称: Nature
• ISSN/ISSBN: 0028-2250
• DOI: 10.1038/d41586-025-01450-z
• 发表日期: 2025-06-26
• 关键词: mosaic loss; blood

摘要

Prognosis is poor for tumours with Y-chromosome loss. Examining the interplay between cancer and immune cells sheds light on potential mechanisms.