8072期

最新文章

• Unravelling cysteine-deficiency-associated rapid weight loss AI翻译
  作者：Varghese, Alan; Gusarov, Ivan; Gamallo-Lana, Begona; Dolgonos, Daria; Mankan, Yatin; Shamovsky, Ilya; Phan, Mydia; Jones, Rebecca; Gomez-Jenkins, Maria; White, Eileen; Wang, Rui; Jones, Drew R.; Papagiannakopoulos, Thales; Pacold, Michael E.; Mar, Adam C.; Littman, Dan R.; Nudler, Evgeny
  作者单位：New York University; New York University; New York University; New York University; Rutgers University System; Rutgers University New Brunswick; Rutgers University Biomedical & Health Sciences; Rutgers Cancer Institute of New Jersey; Rutgers University System; Rutgers University New Brunswick; Princeton University; Ludwig Institute for Cancer Research; York University - Canada; NYU Langone Medical Center; NYU Langone Medical Center; NYU Langone Medical Center; Howard Hughes Medical Institute
  摘要：Around 40% of the US population and 1 in 6 individuals worldwide have obesity, with the incidence surging globally1,2. Various dietary interventions, including carbohydrate, fat and, more recently, amino acid restriction, have been explored to combat this epidemic3, 4, 5-6. Here we investigated the impact of removing individual amino acids on the weight profiles of mice. We show that conditional cysteine restriction resulted in the most substantial weight loss when compared to essential amino ...
• Smart brain-zapping implants could revolutionize Parkinson's treatment AI翻译
  作者：Adee, Sally
  摘要：The next generation of deep-brain stimulation automatically corrects the precise brain waves that create symptoms of Parkinson's disease. Can this approach target other conditions?
• Targeting the SHOC2-RAS interaction in RAS-mutant cancers (vol 642, pg 232, 2025) AI翻译
  作者：Hauseman, Zachary J.; Stauffer, Frederic; Beyer, Kim S.; Molle, Sandra; Cavicchioli, Elena; Marchand, Jean-Remy; Fodor, Michelle; Viscomi, Jessica; Dhembi, Anxhela; Katz, Stephanie; Faggion, Beatrice; Lanter, Mylene; Kerr, Grainne; Schildknecht, Daniela; Handl, Cornelia; Maddalo, Danilo; Pissot Soldermann, Carole; Brady, Jacob; Shrestha, Om; Nguyen, Zachary; Leder, Lukas; Cremosnik, Gregor; Lopez Romero, Sandra; Hassiepen, Ulrich; Stams, Travis; Linder, Markus; Galli, Giorgio G.; Guthy, Daniel A.; King, Daniel A.; Maira, Sauveur-Michel; Thoma, Claudio R.; Ehmke, Veronika; Tordella, Luca
• A motorcycle ride through the forest: how I protect Nigeria's wildlife AI翻译
  作者：Nordling, Linda
  摘要：Emmanuel Barde Elisha is a research coordinator for a non-profit organization dedicated to managing protected areas for conservation and local development.
• A kinase mediator of rhizobial symbiosis and immunity in Medicago AI翻译
  作者：Wang, Dapeng; Jin, Rui; Shi, Xiaobao; Guo, Haoran; Tan, Xinhang; Zhao, Achen; Lian, Xinghua; Dai, Huiling; Li, Shaozhuang; Xin, Kexu; Tian, Changfu; Yang, Jun; Chen, Wansheng; Macho, Alberto P.; Wang, Ertao
  作者单位：Chinese Academy of Sciences; Center for Excellence in Molecular Plant Sciences, CAS; Shanghai University of Traditional Chinese Medicine; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; China Agricultural University; ShanghaiTech University
  摘要：Legume roots secure nitrogen by forming a symbiosis with soil rhizobia but remain resistant to pathogenic bacteria1, 2, 3-4. How this tolerance to rhizobia is achieved without compromising plant immunity is largely unknown. Here we identify the cytoplasmic kinase MtLICK1/2, which interacts with nodulation factor receptor MtLYK3 to drive symbiotic signalling and suppress plant immunity. Rhizobial infection and nodule development are defective in Mtlick1/2, phenocopying the Mtlyk3-1 mutant. MtLI...
• The origin of the oldest solid objects in the Solar System AI翻译
  作者：Ciesla, Fred
  作者单位：University of Chicago
• Sex differences in skin-cancer risk are linked to oestrogen levels AI翻译
  作者：Meierjohann, Svenja
  作者单位：University of Wurzburg
• Rare find: interstellar visitor seen blazing through our Solar System AI翻译
  作者：Jones, Nicola
• A canine friend to a feline family AI翻译
  作者：[Anonymous]
• China's shift towards 'organized research': how can coordination and innovation co-exist? AI翻译
  作者：Han, Shuangmiao; Xie, Jing
  作者单位：Zhejiang University; Zhejiang University of Finance & Economics