作者:Ko, Sangyoon Y.; Rong, Yiming; Ramsaran, Adam I.; Chen, Xiaoyu; Rashid, Asim J.; Mocle, Andrew J.; Dhaliwal, Jagroop; Awasthi, Ankit; Guskjolen, Axel; Josselyn, Sheena A.; Frankland, Paul W.
作者单位:University of Toronto; Hospital for Sick Children (SickKids); University of Toronto; University of Toronto; University of Toronto; University of Toronto; Canadian Institute for Advanced Research (CIFAR)
摘要:Episodic memories-high-fidelity memories for events that depend initially on the hippocampus-do not maintain their precision in perpetuity. One benefit of this time-dependent loss of precision is the emergence of event-linked gist memories that may be used to guide future behaviour in new but related situations (that is, generalization)1, 2-3. Models of systems consolidation propose that memory reorganization accompanies this loss of memory precision1,4; however, the locus of this reorganizati...