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• Weaponizing uncertainty in science and in public health puts people in harm's way AI翻译
  作者：[Anonymous]
• Ancient DNA connects large-scale migration with the spread of Slavs AI翻译
  作者：Gretzinger, Joscha; Biermann, Felix; Mager, Hellen; King, Benedict; Zlamalova, Denisa; Traverso, Luca; Gnecchi Ruscone, Guido A.; Peltola, Sanni; Salmela, Elina; Neumann, Gunnar U.; Radzeviciute, Rita; Ingrova, Pavlina; Liwoch, Radoslaw; Wronka, Iwona; Juric, Radomir; Hyrchala, Anna; Niezabitowska-Wisniewska, Barbara; Bartecki, Bartlomiej; Borowska, Beata; Dzienkowski, Tomasz; Woloszyn, Marcin; Wojenka, Michal; Wilczynski, Jaroslaw; Kot, Malgorzata; Mueller, Eric; Orschiedt, Jorg; Zarina, Gunita; Onkamo, Paivi; Daim, Falko; Muhl, Arnold; Schwarz, Ralf; Majer, Marek; McCormick, Michael; Kvetina, Jan; Vida, Tivadar; Geary, Patrick J.; Machacek, Jiri; Slaus, Mario; Meller, Harald; Pohl, Walter; Hofmanova, Zuzana; Krause, Johannes
  作者单位：Max Planck Society; University of Szczecin; Max Planck Society; Masaryk University; University of Turku; University of Helsinki; Jagiellonian University; Maria Curie-Sklodowska University; Maria Curie-Sklodowska University; University of Lodz; University of Rzeszow; Jagiellonian University; Polish Academy of Sciences; Institute of Systematics & Evolution of Animals of the Polish Academy of Sciences; University of Warsaw; Free University of Berlin; University of Latvia; University of Vienna; University of Lodz; Harvard University; Czech Academy of Sciences; Institute of History of the Czech Academy of Sciences; Eotvos Lorand University; Institute for Advanced Study - USA; Croatian Academy of Sciences & Arts; University of Vienna; Austrian Academy of Sciences
  摘要：The second half of the first millennium ce in Central and Eastern Europe was accompanied by fundamental cultural and political transformations. This period of change is commonly associated with the appearance of the Slavs, which is supported by textual evidence1,2 and coincides with the emergence of similar archaeological horizons3, 4, 5-6. However, so far there has been no consensus on whether this archaeological horizon spread by migration, Slavicisation or a combination of both. Genetic dat...
• Rewiring of cortical glucose metabolism fuels human brain cancer growth AI翻译
  作者：Scott, Andrew J.; Mittal, Anjali; Meghdadi, Baharan; O'Brien, Alexandra; Bailleul, Justine; Sravya, Palavalasa; Achreja, Abhinav; Zhou, Weihua; Xu, Jie; Lin, Angelica; Wilder-Romans, Kari; Liang, Ningning; Kothari, Ayesha U.; Korimerla, Navyateja; Edwards, Donna M.; Wu, Zhe; Feng, Jiane; Su, Sophia; Zhang, Li; Sajjakulnukit, Peter; Andren, Anthony C.; Park, Junyoung O.; ten Hoeve, Johanna; Tarnal, Vijay; Redic, Kimberly A.; Qi, Nathan R.; Fischer, Joshua L.; Yang, Ethan; Regan, Michael S.; Stopka, Sylwia A.; Baquer, Gerard; Suresh, Krithika; Sarkaria, Jann N.; Lawrence, Theodore S.; Venneti, Sriram; Agar, Nathalie Y. R.; Vlashi, Erina; Lyssiotis, Costas A.; Al-Holou, Wajd N.; Nagrath, Deepak; Wahl, Daniel R.
  作者单位：University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of California System; University of California Los Angeles; David Geffen School of Medicine at UCLA; University of California Los Angeles Medical Center; University of California System; UCLA Jonsson Comprehensive Cancer Center; University of California Los Angeles; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; David Geffen School of Medicine at UCLA; University of California Los Angeles Medical Center; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; Bruker Corporation; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Brigham & Women's Hospital; University of Michigan System; University of Michigan; Mayo Clinic; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan
  摘要：The brain avidly consumes glucose to fuel neurophysiology1. Cancers of the brain, such as glioblastoma, relinquish physiological integrity and gain the ability to proliferate and invade healthy tissue2. How brain cancers rewire glucose use to drive aggressive growth remains unclear. Here we infused 13C-labelled glucose into patients and mice with brain cancer, coupled with quantitative metabolic flux analysis, to map the fates of glucose-derived carbon in tumour versus cortex. Through direct a...
• Want to do disruptive science? Include more rookie researchers AI翻译
  作者：Kavanagh, Katie
• Swapping old immune cells in the brain with fresh ones could treat disease AI翻译
  作者：Ledford, Heidi
• Microbe discovery holds promise for sustainable biotechnology AI翻译
  作者：Li, Jie; Liu, Shuwen; Song, Hao; Ding, Shiming
  作者单位：Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; Institute of Microbiology, CAS; Northeastern University - China; Southeast University - China
• See space fireworks and lightning spaghetti - September's best science images AI翻译
  作者：Schwaller, Fred; Kavanagh, Katie
• A ductile chromium-molybdenum alloy resistant to high-temperature oxidation AI翻译
  作者：Hinrichs, Frauke; Winkens, Georg; Kramer, Lena Katharina; Falcao, Gabriely; Hahn, Ewa M.; Schliephake, Daniel; Eusterholz, Michael Konrad; Sen, Sandipan; Galetz, Mathias Christian; Inui, Haruyuki; Kauffmann, Alexander; Heilmaier, Martin
  作者单位：Helmholtz Association; Karlsruhe Institute of Technology; Helmholtz Association; Karlsruhe Institute of Technology; Kyoto University; Kyoto University; Ruhr University Bochum
  摘要：Even with the rapid development of renewable energy sources, improving the efficiency of energy conversion from fossil or synthetic fuels remains a challenge because, for example, combustion engines in long-range aircraft will still be needed in the upcoming decades1. Increasing their operating temperatures (1,050-1,150 degrees C (refs. 2, 3-4)) is one option. This requires replacing single-crystalline Ni-based superalloys in the hottest sections of turbines by refractory-element-based materia...
• Ancient DNA clarifies the early history of the Slavs AI翻译
  作者：Patzold, Steffen
  作者单位：Eberhard Karls University of Tubingen
• A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2 AI翻译
  作者：Vollmer, Benjamin; Ebel, Henriette; Rees, Renate; Nentwig, Julia; Mulvaney, Thomas; Schunemann, Jurgen; Krull, Jens; Topf, Maya; Gorlich, Dirk; Grunewald, Kay
  作者单位：University of Hamburg; University of Hamburg; University Medical Center Hamburg-Eppendorf
  摘要：The nine human herpesviruses, including herpes simplex virus 1 and 2, human cytomegalovirus and Epstein-Barr virus, present a significant burden to global public health1. Their envelopes contain at least ten different glycoproteins, which are necessary for host cell tropism, attachment and entry2. The best conserved among them, glycoprotein B (gB), is essential as it performs membrane fusion by undergoing extensive rearrangements from a prefusion to postfusion conformation. At present, there a...