2025

最新文章

• Computer processors built from 2D materials AI翻译
  作者：Waltl, Michael; Grasser, Tibor
  作者单位：Technische Universitat Wien
• Clever cockatoos learn an easy way to quench their thirst AI翻译
  作者：[Anonymous]
• Ru and W isotope systematics in ocean island basalts reveals core leakage AI翻译
  作者：Messling, Nils; Willbold, Matthias; Kallas, Leander; Elliott, Tim; Fitton, J. Godfrey; Mueller, Thomas; Geist, Dennis
  作者单位：University of Gottingen; University of Bristol; University of Edinburgh; University of Gottingen; Colgate University
  摘要：The isotopic composition of lavas associated with mantle plumes has previously been interpreted in the light of core-mantle interaction, suggesting that mantle plumes may transport core material to Earth's surface1, 2, 3, 4-5. However, a definitive fingerprint of Earth's core in the mantle remains unconfirmed. Precious metals, such as ruthenium (Ru), are highly concentrated in the metallic core but extremely depleted in the silicate mantle. Recently discovered mass-independent Ru isotope varia...
• A message from island leaders: protect the Pacific Ocean from deep-sea mining AI翻译
  作者：Brotherson, Moetai; Whipps Jr, Surangel
• Want to enhance lab safety? Try a little role playing first AI翻译
  作者：Valero, Myriam Vidal
• Age-related blood condition counteracted with a common diabetes drug AI翻译
  作者：Khabusheva, Elmira; Goodell, Margaret A.
  作者单位：Baylor College of Medicine; Baylor College of Medicine
• Milli-spinner thrombectomy AI翻译
  作者：Chang, Yilong; Wu, Shuai; Li, Qi; Pulli, Benjamin; Salmi, Darren; Yock, Paul; Heit, Jeremy J.; Zhao, Ruike Renee
  作者单位：Stanford University; Stanford University; Stanford University; Stanford University
  摘要：Clot-induced blockage in arteries or veins can cause severe medical conditions1. Mechanical thrombectomy is a minimally invasive technique used to treat ischaemic stroke, myocardial infarction, pulmonary embolism and peripheral vascular disease2, 3-4 by removing clots through aspiration5, stent retriever6 or cutting mechanisms7. However, current mechanical thrombectomy methods fail to remove clots in 10-30% of patients8, 9-10, especially in the case of large, fibrin-rich clots11. These methods...
• Small molecules restore mutant mitochondrial DNA polymerase activity AI翻译
  作者：Valenzuela, Sebastian; Zhu, Xuefeng; Macao, Bertil; Stamgren, Mattias; Geukens, Carol; Charifson, Paul S.; Kern, Gunther; Hoberg, Emily; Jenninger, Louise; Gruszczyk, Anja V.; Lee, Seoeun; Johansson, Katarina A. S.; Fuste, Javier Miralles; Shi, Yonghong; Kerns, S. Jordan; Arabanian, Laleh; Botella, Gabriel Martinez; Ekstroem, Sofie; Green, Jeremy; Griffin, Andrew M.; Pardo-Hernandez, Carlos; Keating, Thomas A.; Kuppers-Munther, Barbara; Larsson, Nils-Goran; Phan, Cindy; Posse, Viktor; Jones, Juli E.; Xie, Xie; Giroux, Simon; Gustafsson, Claes M.; Falkenberg, Maria
  作者单位：University of Gothenburg; Karolinska Institutet
  摘要：Mammalian mitochondrial DNA (mtDNA) is replicated by DNA polymerase gamma (POL gamma), a heterotrimeric complex consisting of a catalytic POL gamma A subunit and two accessory POL gamma B subunits1. More than 300 mutations in POLG, the gene encoding the catalytic subunit, have been linked to severe, progressive conditions with high rates of morbidity and mortality, for which no treatment exists2. Here we report on the discovery and characterization of PZL-A, a first-in-class small-molecule act...
• Mathematics in ancient Egypt AI翻译
  作者：[Anonymous]
• Painting restored with a digitally constructed mask AI翻译
  作者：Kutzke, Hartmut
  作者单位：University of Oslo