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作者:Jafferis, Daniel; Zlokapa, Alexander; Lykken, Joseph D.; Kolchmeyer, David K.; Davis, Samantha I.; Lauk, Nikolai; Neven, Hartmut; Spiropulu, Maria
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作者:Silver, Lynn L.
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作者:Biever, Celeste
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作者:Fieldhouse, Rachel
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作者:Correia, Ana Luisa
作者单位:Fundacao Champalimaud
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作者:Jia, Gengjie; He, Peiqi; Dai, Tianli; Goh, Denise; Wang, Jiabei; Sun, Mengyuan; Wee, Felicia; Li, Fuling; Lim, Jeffrey Chun Tatt; Hao, Shuxia; Liu, Yao; Lim, Tony Kiat Hon; Ngo, Nye-Thane; Tao, Qingping; Wang, Wei; Umar, Ahitsham; Nashan, Bjoern; Zhang, Yongchang; Ding, Chen; Yeong, Joe; Liu, Lianxin; Sun, Cheng
作者单位:Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Agricultural Sciences; Agriculture Genomes Institute at Shenzhen, CAAS; Agency for Science Technology & Research (A*STAR); A*STAR - Institute of Molecular & Cell Biology (IMCB); National University of Singapore; Central South University; Fudan University; Fudan University; Singapore General Hospital; Agency for Science Technology & Research (A*STAR); A*STAR - Singapore Immunology Network (SIgN); National University of Singapore
摘要:Given the high recurrence rates of hepatocellular carcinoma (HCC) post-resection(1, 2-3), improved early identification of patients at high risk for post-resection recurrence would help to improve patient outcomes and prioritize healthcare resources(4, 5-6). Here we observed a spatial and HCC recurrence-associated distribution of natural killer (NK) cells in the invasive front and tumour centre from 61 patients. Using extreme gradient boosting and inverse-variance weighting, we developed the t...
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作者:Liu, Ding; Rahman, Mostafizur; Johnson, Autumn; Amo, Ryunosuke; Tsutsui-Kimura, Iku; Sullivan, Zuri A.; Pena, Nicolai; Talay, Mustafa; Logeman, Brandon L.; Finkbeiner, Samantha; Qian, Lechen; Choi, Seungwon; Capo-Battaglia, Athena; Abdus-Saboor, Ishmail; Ginty, David D.; Uchida, Naoshige; Watabe-Uchida, Mitsuko; Dulac, Catherine
作者单位:Harvard University; Howard Hughes Medical Institute; Harvard University; Harvard University; Harvard Medical School; Howard Hughes Medical Institute; Columbia University; Keio University; University of Texas System; University of Texas Southwestern Medical Center
摘要:Social grouping increases survival in many species, including humans1,2. By contrast, social isolation generates an aversive state ('loneliness') that motivates social seeking and heightens social interaction upon reunion3, 4-5. The observed rebound in social interaction triggered by isolation suggests a homeostatic process underlying the control of social need, similar to physiological drives such as hunger, thirst or sleep3,6. In this study, we assessed social responses in several mouse stra...
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作者:Antonelli, Alexandre; Chater, Caspar; Strassburg, Bernardo; Balmford, Andrew
作者单位:Royal Botanic Gardens, Kew; University of Cambridge
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作者:Nordling, Linda; Nzioki, Henry Sila
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作者:Robinson, Andrew