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作者：Callahan, Christopher W.; Mankin, Justin S.
作者单位：Dartmouth College; Dartmouth College; Dartmouth College; Columbia University
摘要：Will it ever be possible to sue anyone for damaging the climate? Twenty years after this question was first posed, we argue that the scientific case for climate liability is closed. Here we detail the scientific and legal implications of an 'end-to-end' attribution that links fossil fuel producers to specific damages from warming. Using scope 1 and 3 emissions data from major fossil fuel companies, peer-reviewed attribution methods and advances in empirical climate economics, we illustrate the...
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作者：Sharma, Pranav
作者单位：Department of Science & Technology (India); Raman Research Institute (RRI)
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作者：Jangra, Manoj; Travin, Dmitrii Y.; Aleksandrova, Elena V.; Kaur, Manpreet; Darwish, Lena; Koteva, Kalinka; Klepacki, Dorota; Wang, Wenliang; Tiffany, Maya; Sokaribo, Akosiererem; Coombes, Brian K.; Vazquez-Laslop, Nora; Polikanov, Yury S.; Mankin, Alexander S.; Wright, Gerard D.
作者单位：McMaster University; McMaster University; McMaster University; University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital; University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital; University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital
摘要：Lasso peptides (biologically active molecules with a distinct structurally constrained knotted fold) are natural products that belong to the class of ribosomally synthesized and post-translationally modified peptides1, 2-3. Lasso peptides act on several bacterial targets4,5, but none have been reported to inhibit the ribosome, one of the main targets of antibiotics in the bacterial cell6,7. Here we report the identification and characterization of the lasso peptide antibiotic lariocidin and it...
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作者：Eisenstein, Michael
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作者：Nelson, Felicity; Ong, Sandy
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作者：Winkler, P.; Trunk, M.; Huebner, L.; de la Ossa, A. Martinez; Jalas, S.; Kirchen, M.; Agapov, I.; Antipov, S. A.; Brinkmann, R.; Eichner, T.; Pousa, A. Ferran; Huelsenbusch, T.; Palmer, G.; Schnepp, M.; Schubert, K.; Thevenet, M.; Walker, P. A.; Werle, C.; Leemans, W. P.; Maier, A. R.
作者单位：Helmholtz Association; Deutsches Elektronen-Synchrotron (DESY); University of Hamburg
摘要：Radio-frequency (RF) accelerators providing high-quality relativistic electron beams are an important resource enabling many areas of science, as well as industrial and medical applications. Two decades ago, laser-plasma accelerators1 that support orders of magnitude higher electric fields than those provided by modern RF cavities produced quasi-monoenergetic electron beams for the first time2, 3-4. Since then, high-brightness electron beams at gigaelectronvolt (GeV) beam energy and competitiv...
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作者：Yang, Jie; Yamashita-Kanemaru, Yumi; Morris, Benjamin I.; Contursi, Annalisa; Trajkovski, Daniel; Xu, Jingru; Patrascan, Ilinca; Benson, Jayme; Evans, Alexander C.; Conti, Alberto G.; Al-Deka, Aws; Dahmani, Layla; Avdic-Belltheus, Adnan; Zhang, Baojie; Okkenhaug, Hanneke; Whiteside, Sarah K.; Imianowski, Charlotte J.; Wesolowski, Alexander J.; Webb, Louise V.; Puccio, Simone; Tacconelli, Stefania; Bruno, Annalisa; Di Berardino, Sara; De Michele, Alessandra; Welch, Heidi C. E.; Yu, I-Shing; Lin, Shu-Wha; Mitra, Suman; Lugli, Enrico; van der Weyden, Louise; Okkenhaug, Klaus; Saeb-Parsy, Kourosh; Patrignani, Paola; Adams, David J.; Roychoudhuri, Rahul
作者单位：University of Cambridge; G d'Annunzio University of Chieti-Pescara; G d'Annunzio University of Chieti-Pescara; University of Cambridge; University of Cambridge; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC); Babraham Institute; Francis Crick Institute; National Taiwan University; National Taiwan University; Universite de Lille; Institut National de la Sante et de la Recherche Medicale (Inserm); CHU Lille; Wellcome Trust Sanger Institute; G d'Annunzio University of Chieti-Pescara
摘要：Metastasis is the spread of cancer cells from primary tumours to distant organs and is the cause of 90% of cancer deaths globally1,2. Metastasizing cancer cells are uniquely vulnerable to immune attack, as they are initially deprived of the immunosuppressive microenvironment found within established tumours3. There is interest in therapeutically exploiting this immune vulnerability to prevent recurrence in patients with early cancer at risk of metastasis. Here we show that inhibitors of cycloo...
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作者：Pittaluga, Mirko; Lo, Yuen San; Brzosko, Adam; Woodward, Robert I.; Scalcon, Davide; Winnel, Matthew S.; Roger, Thomas; Dynes, James F.; Owen, Kim A.; Juarez, Sergio; Rydlichowski, Piotr; Vicinanza, Domenico; Roberts, Guy; Shields, Andrew J.
作者单位：Toshiba Corporation; Polish Academy of Sciences; Poznan Supercomputing & Networking Center; Anglia Ruskin University
摘要：Recent advances in quantum communications have underscored the crucial role of optical coherence in developing quantum networks. This resource, which is fundamental to the phase-based architecture of the quantum internet1, has enabled the only successful demonstrations of multi-node quantum networks2, 3-4 and substantially extended the range of quantum key distribution (QKD)5. However, the scalability of coherence-based quantum protocols remains uncertain owing to the specialized hardware requ...
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作者：[Anonymous]
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作者：Briggs, Derek E. G.
作者单位：Yale University
