Science

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• Why three scientists said no to Epstein AI翻译
  作者：Mervis, Jeffrey
• An unconventional Rubisco small subunit underpins the CO2-concentrating organelle in land plants AI翻译
  作者：Robison, Tanner A.; Mao, Yuwei; Oh, Zhen Guo; Ang, Warren S. L.; Loh, Dan Hong; Hsieh, Yu-Heng; Ceminsky, Maddie; Atkinson, Nicky; Lafferty, Declan; Xu, Xia; Gunn, Laura H.; McCormick, Alistair J.; Li, Fay-Wei
  作者单位：Cornell University; Boyce Thompson Institute for Plant Research; Cornell University; University of Edinburgh; University of Edinburgh; Cornell University
  摘要：In many algae, photosynthesis is boosted by biophysical CO2-concentrating mechanisms, which pack the CO2-fixing enzyme Rubisco into liquid-like organelles called pyrenoids. Engineering C3 crops with algal pyrenoids could increase yields, but progress is hampered by the deep evolutionary divide between crops and algae. Here, we show that hornworts, the only land plants with pyrenoids, have an unusual Rubisco small subunit, RbcS-STAR, the C-terminal coiled-coil domain of which oligomerizes to me...
• Poland: No country for PhD researchers AI翻译
  作者：Zukowski, Alan; Stepien, Martyna
  作者单位：University of Wroclaw
• The Traversal AI翻译
  作者：Ball, Philip
• Black holes disguised as little red dots AI翻译
  作者：Matthee, Jorryt
  作者单位：Institute of Science & Technology - Austria
• More than mitigation: The role of forests in climate adaptation AI翻译
  作者：Reek, Josephine Elena; Zohner, Constantin M.; Smith, Gabriel Reuben; Cook-Patton, Susan C.; De Frenne, Pieter; D'odorico, Paolo; Floriancic, Marius G.; Jackson, Robert B.; Jones, Julia A.; Kirchner, James W.; Lague, Marysa; Liang, Yuting; Masuda, Yuta J.; McDonald, Robert I.; Parsons, Luke A.; Probst, Benedict S.; Spector, June T.; West, Thales A. P.; Wolff, Nicholas H.; Zellweger, Florian; Crowther, Thomas W.
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich; Nature Conservancy; Ghent University; University of California System; University of California Berkeley; University of California System; University of California Berkeley; Swiss Federal Institutes of Technology Domain; ETH Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich; Stanford University; Stanford University; Oregon State University; Swiss Federal Institutes of Technology Domain; Swiss Federal Institute for Forest, Snow & Landscape Research; Swedish University of Agricultural Sciences; University of British Columbia; Chinese Academy of Sciences; Nanjing Institute of Soil Science, CAS; City University of New York (CUNY) System; Humboldt University of Berlin; Utah System of Higher Education; University of Utah; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Cambridge; University of Washington; University of Washington Seattle; Vrije Universiteit Amsterdam; Nature Conservancy; King Abdullah University of Science & Technology
  摘要：Forests regulate global and local climates in ways that impact human well-being. In this Review, we discuss the scale-dependent mechanisms through which forests regulate climate, highlighting their contributions to global mitigation and local adaptation. Locally, forests tend to buffer temperatures, cooling in warm conditions and warming in cold ones. In regions that naturally support dense forest cover, trees contribute to global cooling primarily through carbon uptake, with some offsetting f...
• RNA comes close to copying itself AI翻译
  作者：Service, Robert F.
• Bonded by Evolution: The New Science of Love and Connection AI翻译
  作者：Brooks, Robert C.
  作者单位：University of New South Wales Sydney; University of New South Wales Sydney
• Softening the blow AI翻译
  作者：Cho, Adrian
• Antifibrotic drug finerenone restores fertility in premature ovarian insufficiency AI翻译
  作者：Lin, Zexiong; Li, Yuan; Zhao, Yu; Liu, Dongteng; Deng, Shuzi; Gu, Jingkai; Li, Yanyan; Zhao, Xudong; Wu, Peishan; Xiao, Yuan; Su, Jiaping; Sun, Yiting; Zhang, Yihui; Lee, Yin Lau; Sato, Yorino; Zeng, Haitao; Lu, Haonan; Zhang, Juanhui; Ko, Jennifer K. Y.; Zhao, Jing; Kawamura, Kazuhiro; Ng, Ernest H. Y.; Jiang, Shanfang; Li, Yu; Xia, Xi; Chan, Karen K. L.; Yeung, William S. B.; Wang, Tianren R.; Liu, Kui
  作者单位：University of Hong Kong; University of Hong Kong; Juntendo University; Sun Yat Sen University; Peking University
  摘要：Currently, no effective treatment exists for infertility associated with premature ovarian insufficiency (POI) because affected patients lack hormone-responsive antral follicles. By screening a Food and Drug Administration (FDA)-approved drug library, we identified finerenone, a kidney disease medication, as a promising drug for restoring fertility in POI. Finerenone stimulated follicle development in aged mice and restored antral follicle development in patients with POI following oral admini...