Science

最新文章

• The ins and outs of circulating DNA AI翻译
  作者：Tsui, W. H. Adrian; Lo, Y. M. Dennis
  作者单位：Chinese University of Hong Kong; Chinese University of Hong Kong; Chinese University of Hong Kong
• Leading a lab, and all it entails AI翻译
  作者：Wai, Jonathan
  作者单位：University of Arkansas System; University of Arkansas Fayetteville; University of Arkansas System; University of Arkansas Fayetteville
• The proteome of the late Middle Pleistocene Harbin individual AI翻译
  作者：Fu, Qiaomei; Bai, Fan; Rao, Huiyun; Chen, Shaokun; Ji, Yannan; Liu, Aoran; Bennett, E. Andrew; Liu, Feng; Ji, Qiang
  作者单位：Chinese Academy of Sciences; Institute of Vertebrate Paleontology & Paleoanthropology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Hebei GEO University; China Geological Survey; Chinese Academy of Geological Sciences
  摘要：Denisovans are a hominin group primarily known through genomes or proteins, but their precise morphological features remain elusive because of the fragmentary nature of the discovered fossils. Here, we report 95 endogenous proteins retrieved from a nearly complete cranium from Harbin, China, dating to at least 146,000 years ago and previously assigned to a new species, Homo longi. This individual has three Denisovan-derived amino acid variants and clusters with Denisova 3, suggesting that the ...
• How I learned to ride AI翻译
  作者：Hamzehpoor, Ehsan
  作者单位：Universite de Montreal
• Twist on PET unlocks hidden signals AI翻译
  作者：Savitsky, Zack
• The multifunctional immune system AI翻译
  作者：Ross, Sarah; Ash, Caroline
• Single-photon detection enabled by negative differential conductivity in moiré superlattices AI翻译
  作者：Nowakowski, Krystian; Agarwal, Hitesh; Slizovskiy, Sergey; Smeyers, Robin; Wang, Xueqiao; Zheng, Zhiren; Barrier, Julien; Barcons Ruiz, David; Li, Geng; Bertini, Riccardo; Ceccanti, Matteo; Torre, Iacopo; Jorissen, Bert; Reserbat-Plantey, Antoine; Watanabe, Kenji; Taniguchi, Takashi; Covaci, Lucian; Milosevic, Milorad V.; Falko, Vladimir; Jarillo-Herrero, Pablo; Krishna Kumar, Roshan; Koppens, Frank H. L.
  作者单位：Barcelona Institute of Science & Technology; Universitat Politecnica de Catalunya; Institut de Ciencies Fotoniques (ICFO); University of Manchester; University of Antwerp; University of Antwerp; Massachusetts Institute of Technology (MIT); Universitat Politecnica de Catalunya; Universite Cote d'Azur; Centre National de la Recherche Scientifique (CNRS); National Institute for Materials Science; National Institute for Materials Science; Barcelona Institute of Science & Technology; Catalan Institute of Nanoscience & Nanotechnology (ICN2); Consejo Superior de Investigaciones Cientificas (CSIC); Barcelona Institute of Science & Technology; ICREA
  摘要：Detecting individual light quanta is essential for quantum information, space exploration, advanced machine vision, and fundamental science. In this work, we introduce a single-photon detection mechanism using highly photosensitive nonequilibrium electron phases in moir & eacute; materials. Using tunable bands in bilayer graphene/hexagonal boron nitride superlattices, we engineer negative differential conductance and a sensitive bistable state capable of detecting single photons. Operating in ...
• Brazil's dangerous environmental licensing bill AI翻译
  作者：Weidlich, Emanuela W. A.
  作者单位：Leuphana University Luneburg
• Convergence and divergence of individual immune responses over the life course AI翻译
  作者：Metcalf, C. Jessica E.; Graham, Andrea L.; Yates, Andrew J.; Cummings, Derek A. T.
  作者单位：Princeton University; Princeton University; The Santa Fe Institute; Columbia University; NewYork-Presbyterian Hospital; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Johns Hopkins University
  摘要：Three ingredients create the strikingly variable immune trajectories observed across human populations: (i) genetic variation, (ii) individual-scale generation of additional genetic diversity solely in lymphocytes, and (iii) collision of these processes with a changing environment through life, triggering plastic responses that can have lasting effects. We explore what generates or reduces immune variation, integrating recent empirical advances with potential overarching evolutionary principle...
• Sex differences in tissue-specific immunity and immunology AI翻译
  作者：Sharma, Sonia; Gibbons, Alicia; Saphire, Erica Ollmann
  作者单位：La Jolla Institute for Immunology; RIKEN; University of California System; University of California San Diego
  摘要：Biological sex exerts a substantial influence on the immune system and immune-related diseases. Males are more susceptible to the acute effects of viral disease and certain cancers, whereas females exhibit a more robust immune response that can make them prone to developing autoimmune complications. We reflect on the emerging appreciation of sex differences-governed by genetics, sex hormones, and environmental factors-in tissue immunity and immunology. Understanding these tissue context-depend...