作者:Ju, Xiangwu; Li, Shuqi; Froom, Ruby; Wang, Ling; Lilic, Mirjana; Delbeau, Madeleine; Campbell, Elizabeth A.; Rock, Jeremy M.; Liu, Shixin
作者单位:Rockefeller University; Rockefeller University; Rockefeller University
摘要:Mycobacterium tuberculosis (Mtb) is a bacterial pathogen that causes tuberculosis (TB), an infectious disease that is responsible for major health and economic costs worldwide1. Mtb encounters diverse environments during its life cycle and responds to these changes largely by reprogramming its transcriptional output2. However, the mechanisms of Mtb transcription and how they are regulated remain poorly understood. Here we use a sequencing method that simultaneously determines both termini of i...
作者:Abuter, R.; Allouche, F.; Amorim, A.; Bailet, C.; Berdeu, A.; Berger, J. -P.; Berio, P.; Bigioli, A.; Boebion, O.; Bolzer, M. -L.; Bonnet, H.; Bourdarot, G.; Bourget, P.; Brandner, W.; Cao, Y.; Conzelmann, R.; Comin, M.; Clenet, Y.; Courtney-Barrer, B.; Davies, R.; Defrere, D.; Delboulbe, A.; Delplancke-Stroebele, F.; Dembet, R.; Dexter, J.; de Zeeuw, P. T.; Drescher, A.; Eckart, A.; Edouard, C.; Eisenhauer, F.; Fabricius, M.; Feuchtgruber, H.; Finger, G.; Schreiber, N. M. Foerster; Garcia, P.; Lopez, R. Garcia; Gao, F.; Gendron, E.; Genzel, R.; Gil, J. P.; Gillessen, S.; Gomes, T.; Gonte, F.; Gouvret, C.; Guajardo, P.; Guieu, S.; Hackenberg, W.; Haddad, N.; Hartl, M.; Haubois, X.; Haussmann, F.; Heissel, G.; Henning, Th.; Hippler, S.; Honig, S. F.; Horrobin, M.; Hubin, N.; Jacqmart, E.; Jocou, L.; Kaufer, A.; Kervella, P.; Kolb, J.; Korhonen, H.; Lacour, S.; Lagarde, S.; Lai, O.; Lapeyrere, V.; Laugier, R.; Le Bouquin, J. -B.; Leftley, J.; Lena, P.; Lewis, S.; Liu, D.; Lopez, B.; Lutz, D.; Magnard, Y.; Mang, F.; Marcotto, A.; Maurel, D.; Merand, A.; Millour, F.; More, N.; Netzer, H.; Nowacki, H.; Nowak, M.; Oberti, S.; Ott, T.; Pallanca, L.; Paumard, T.; Perraut, K.; Perrin, G.; Petrov, R.; Pfuhl, O.; Pourre, N.; Rabien, S.; Rau, C.; Riquelme, M.; Robbe-Dubois, S.; Rochat, S.; Salman, M.; Sanchez-Bermudez, J.; Santos, D. J. D.; Scheithauer, S.; Schoeller, M.; Schubert, J.; Schuhler, N.; Shangguan, J.; Shchekaturov, P.; Shimizu, T. T.; Sevin, A.; Soulez, F.; Spang, A.; Stadler, E.; Sternberg, A.; Straubmeier, C.; Sturm, E.; Sykes, C.; Tacconi, L. J.; Tristram, K. R. W.; Vincent, F.; von Fellenberg, S.; Uysal, S.; Widmann, F.; Wieprecht, E.; Wiezorrek, E.; Woillez, J.; Zins, G.
作者单位:Universite Cote d'Azur; Observatoire de la Cote d'Azur; Centre National de la Recherche Scientifique (CNRS); European Southern Observatory; Universidade de Lisboa; Universidade de Lisboa; Universite Paris Cite; Centre National de la Recherche Scientifique (CNRS); Universite PSL; Observatoire de Paris; Sorbonne Universite; Centre National de la Recherche Scientifique (CNRS); Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); Institut de Planetologie et d'Astrophysique de Grenoble (IPAG); KU Leuven; Max Planck Society; Technical University of Munich; Ecole Normale Superieure de Lyon (ENS de LYON); Universite Claude Bernard Lyon 1; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Earth Sciences & Astronomy (INSU); European Southern Observatory; Max Planck Society; Australian National University; University of Colorado System; University of Colorado Boulder; Leiden University; Leiden University - Excl LUMC; Max Planck Society; University of Cologne; Universidade do Porto; University College Dublin; University of California System; University of California Berkeley; University of California System; University of California Berkeley; European Space Agency; European Space Research & Technology Centre; University of Southampton; Tel Aviv University; University of Cambridge; Universidad Nacional Autonoma de Mexico; Simons Foundation; Flatiron Institute
摘要:Tight relationships exist in the local Universe between the central stellar properties of galaxies and the mass of their supermassive black hole (SMBH)1-3. These suggest that galaxies and black holes co-evolve, with the main regulation mechanism being energetic feedback from accretion onto the black hole during its quasar phase4-6. A crucial question is how the relationship between black holes and galaxies evolves with time; a key epoch to examine this relationship is at the peaks of star form...