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作者：Velasco, Silvia
作者单位：Murdoch Children's Research Institute
摘要：A therapeutic strategy that alters gene expression in a rare and severe neurodevelopmental condition has been tested in stem-cell-based models of the disease, and has been shown to correct genetic and cellular defects.
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作者：Leeming, Jack
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作者：Watson, Joseph L.; Seinkmane, Estere; Styles, Christine T.; Mihut, Andrei; Kruger, Lara K.; McNally, Kerrie E.; Planelles-Herrero, Vicente Jose; Dudek, Michal; McCall, Patrick M.; Barbiero, Silvia; Oever, Michael Vanden; Peak-Chew, Sew Yeu; Porebski, Benjamin T.; Zeng, Aiwei; Rzechorzek, Nina M.; Wong, David C. S.; Beale, Andrew D.; Stangherlin, Alessandra; Riggi, Margot; Iwasa, Janet; Morf, Jorg; Miliotis, Christos; Guna, Alina; Inglis, Alison J.; Brugues, Jan; Voorhees, Rebecca M.; Chambers, Joseph E.; Meng, Qing-Jun; O'Neill, John S.; Edgar, Rachel S.; Derivery, Emmanuel
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作者：Marlow, Bonnie L. S.; Hirschauer, Jonathan
作者单位：MITRE Corporation
摘要：A highly precise timekeeping instrument has been adapted for the real world. The compact and robust device is smaller than its commercial counterparts and performs comparably in the laboratory and aboard a naval ship.
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作者：Mohammadi, Alireza; Azareh, Ali; Khanjani, Mohammad Hossein; Sharifinia, Moslem
摘要：Letter to the Editor
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作者：Benevento, Marco; Alpar, Alan; Gundacker, Anna; Afjehi, Leila; Balueva, Kira; Hevesi, Zsofia; Hanics, Janos; Rehman, Sabah; Pollak, Daniela D.; Lubec, Gert; Wulff, Peer; Prevot, Vincent; Horvath, Tamas L.; Harkany, Tibor
作者单位：Medical University of Vienna; Semmelweis University; Semmelweis University; Medical University of Vienna; Paracelsus Private Medical University; University of Kiel; Universite de Lille; Institut National de la Sante et de la Recherche Medicale (Inserm); CHU Lille; Yale University
摘要：Empirical evidence suggests that heat exposure reduces food intake. However, the neurocircuit architecture and the signalling mechanisms that form an associative interface between sensory and metabolic modalities remain unknown, despite primary thermoceptive neurons in the pontine parabrachial nucleus becoming well characterized(1). Tanycytes are a specialized cell type along the wall of the third ventricle(2) that bidirectionally transport hormones and signalling molecules between the brain's...
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作者：Castelvecchi, Davide
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作者：Melis, Johan M.; Siwanowicz, Igor; Dickinson, Michael H.
作者单位：California Institute of Technology; Howard Hughes Medical Institute
摘要：Insects constitute the most species-rich radiation of metazoa, a success that is due to the evolution of active flight. Unlike pterosaurs, birds and bats, the wings of insects did not evolve from legs1, but are novel structures that are attached to the body via a biomechanically complex hinge that transforms tiny, high-frequency oscillations of specialized power muscles into the sweeping back-and-forth motion of the wings2. The hinge consists of a system of tiny, hardened structures called scl...
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作者：[Anonymous]
摘要：The valley degree of freedom(1-4) of electrons in materials promises routes towards energy-efficient information storage with enticing prospects for quantum information processing(5-7). Current challenges in utilizing valley polarization are symmetry conditions that require monolayer structures(8,9) or specific material engineering(10-13), non-resonant optical control to avoid energy dissipation and the ability to switch valley polarization at optical speed. We demonstrate all-optical and non-...
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作者：[Anonymous]
摘要：The United Kingdom is correct to attempt to end the single largest preventable cause of illness and death, as was New Zealand before its government changed its mind.
