作者:Todesco, Marco; Rieseberg, Loren H.
作者单位:University of British Columbia; University of British Columbia; University of British Columbia
作者:Leifer, Andrew M.; Liu, Andrea J.; Nagel, Sidney R.
作者单位:Princeton University; Princeton University; National Academies of Sciences, Engineering & Medicine; University of Pennsylvania; University of Chicago
作者:Teske, Andreas
作者单位:University of North Carolina; University of North Carolina Chapel Hill
作者:Qi, Jiaxuan; Schreiner, Drew C.; Martinez, Miles; Pearson, John; Mooney, Richard
作者单位:Duke University; Duke University; Duke University
摘要:Although learning in response to extrinsic reinforcement is theorized to be driven by dopamine signals that encode the difference between expected and experienced rewards1,2, skills that enable verbal or musical expression can be learned without extrinsic reinforcement. Instead, spontaneous execution of these skills is thought to be intrinsically reinforcing3,4. Whether dopamine signals similarly guide learning of these intrinsically reinforced behaviours is unknown. In juvenile zebra finches ...
作者:Tollefson, Jeff; Garisto, Dan; Kozlov, Max; Witze, Alexandra
作者:Peijnenburg, Willie
作者单位:Leiden University; Leiden University - Excl LUMC; Netherlands National Institute for Public Health & the Environment
摘要:Evidence for a previously overlooked route for microplastics to enter crops and reach plant tissues has implications for ecology and human health.
作者:Mosharov, Eugene V.; Rosenberg, Ayelet M.; Monzel, Anna S.; Osto, Corey A.; Stiles, Linsey; Rosoklija, Gorazd B.; Dwork, Andrew J.; Bindra, Snehal; Junker, Alex; Zhang, Ya; Fujita, Masashi; Mariani, Madeline B.; Bakalian, Mihran; Sulzer, David; De Jager, Philip L.; Menon, Vilas; Shirihai, Orian S.; Mann, J. John; Underwood, Mark D.; Boldrini, Maura; Thiebaut de Schotten, Michel; Picard, Martin
作者单位:NewYork-Presbyterian Hospital; Columbia University; New York State Psychiatry Institute; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; Columbia University; NewYork-Presbyterian Hospital; Columbia University; NewYork-Presbyterian Hospital; Columbia University; NewYork-Presbyterian Hospital; Columbia University; NewYork-Presbyterian Hospital; Columbia University; Columbia University; NewYork-Presbyterian Hospital; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); CEA; Universite de Bordeaux; Columbia University; NewYork-Presbyterian Hospital; Columbia University
摘要:Mitochondrial oxidative phosphorylation (OXPHOS) powers brain activity(1,2), and mitochondrial defects are linked to neurodegenerative and neuropsychiatric disorders(3,4). To understand the basis of brain activity and behaviour, there is a need to define the molecular energetic landscape of the brain(5-10). Here, to bridge the scale gap between cognitive neuroscience and cell biology, we developed a physical voxelization approach to partition a frozen human coronal hemisphere section into 703 ...