8088期

最新文章

• Oxidative potential of atmospheric particles in Europe and exposure scenarios AI翻译
  作者：Tassel, Cecile; Jaffrezo, Jean-Luc; Dominutti, Pamela; Daellenbach, Kaspar R.; Darfeuil, Sophie; Elazzouzi, Rhabira; Laj, Paolo; Marsal, Anouk; Mhadhbi, Takoua; Dinh, Vy Ngoc Thuy; Voiron, Celine; Houdier, Stephan; Durif, Marc; Chatain, Melodie; Francony, Florie; Cozic, Julie; Salque Moreton, Guillaume; Le Quilleuc, Meryll; Ghersi, Veronique; Gille, Gregory; Mesbah, Boualem; Stratigou, Evdokia; Zublena, Manuela; Diemoz, Henri; Alastuey, Andres; D'Anna, Barbara; Marchand, Nicolas; Conil, Sebastien; Gros, Valerie; van Os, Marloes F.; Salma, Imre; Mihalopoulos, Nikolaos; Mocnik, Grisa; Dzepina, Katja; Styszko, Katarzyna; Huglin, Christoph; Querol, Xavier; Prevot, Andre S. H.; Favez, Olivier; Siroux, Valerie; Uzu, Gaelle
  作者单位：Communaute Universite Grenoble Alpes; Centre National de la Recherche Scientifique (CNRS); INRAE; Institut de Recherche pour le Developpement (IRD); Institut National Polytechnique de Grenoble; Universite Grenoble Alpes (UGA); Communaute Universite Grenoble Alpes; Institut National de la Sante et de la Recherche Medicale (Inserm); Centre National de la Recherche Scientifique (CNRS); Universite Grenoble Alpes (UGA); CNRS - National Institute for Biology (INSB); University of Helsinki; Institut National de l'Environnement Industriel et des Risques (INERIS); Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Centro de Investigacion y Desarrollo Pascual Vila (CID-CSIC); CSIC - Instituto de Diagnostico Ambiental y Estudios del Agua (IDAEA); Aix-Marseille Universite; Centre National de la Recherche Scientifique (CNRS); CEA; Universite Paris Saclay; Centre National de la Recherche Scientifique (CNRS); Netherlands Organization Applied Science Research; Hungarian Academy of Sciences; Eotvos Lorand University; Chemical Research Center - HAS; National Observatory of Athens; University of Crete; University of Nova Gorica; AGH University of Krakow; Swiss Federal Institutes of Technology Domain; Swiss Federal Laboratories for Materials Science & Technology (EMPA)
  摘要：Atmospheric particulate matter (PM), a public health concern worldwide, is at present regulated according to its mass concentration1. However, it is increasingly thought that mass concentration may not fully capture the physicochemical properties of PM linked to its health impact2. Consequently, it has been suggested to further investigate the adequacy of this metric as an unequivocal indicator of PM health effects3, 4-5. The new European regulation on air quality introduced oxidative potentia...
• AI uses medical records to accurately predict onset of disease 20 years into the future AI翻译
  作者：Wu, Yonghui
  作者单位：State University System of Florida; University of Florida; State University System of Florida; University of Florida
• When will Africa have a Nobel prize in medicine? AI翻译
  作者：Aderinto, Nicholas
• Japan's first female prime minister doesn't call herself a feminist - but the country needs her to tackle sexism in science AI翻译
  作者：Shimuta, Misa
  作者单位：Jikei University
• US PhD admissions shrink as fears over Trump's cuts take hold AI翻译
  作者：Witze, Alexandra
  摘要：Some doctoral programmes are admitting no students at all amid uncertainty about federal science funding.
• Ocean warming threatens the viability of 60% of Antarctic ice shelves AI翻译
  作者：Burgard, C.; Jourdain, N. C.; Mosbeux, C.; Caillet, J.; Mathiot, P.; Kittel, C.
  作者单位：Centre National de la Recherche Scientifique (CNRS); Museum National d'Histoire Naturelle (MNHN); Institut de Recherche pour le Developpement (IRD); Sorbonne Universite; Institut de Recherche pour le Developpement (IRD); INRAE; Communaute Universite Grenoble Alpes; Centre National de la Recherche Scientifique (CNRS); Institut National Polytechnique de Grenoble; Universite Grenoble Alpes (UGA); Dartmouth College; Vrije Universiteit Brussel
  摘要：The disappearance of ice shelves, the floating margins of the Antarctic ice sheet that restrain the ice flow into the ocean1, 2-3, would strongly accelerate the Antarctic contribution to sea-level rise4, 5-6. Their viability in a warming world has motivated substantial work that focuses on the influence of the warming atmosphere7, 8, 9-10. Here we revisit the concept of ice-shelf viability in a holistic manner, taking into account mass loss due to both the atmosphere and the ocean to estimate ...
• Can IVF save the northern white rhino from extinction? - October's best science images AI翻译
  作者：Schwaller, Fred; Kavanagh, Katie
• A human-specific regulatory mechanism revealed in a pre-implantation model AI翻译
  作者：Fueyo, Raquel; Wang, Sicong; Crocker, Olivia J.; Swigut, Tomek; Nakauchi, Hiromitsu; Wysocka, Joanna
  作者单位：Stanford Medicine; Stanford University; Stanford Medicine; Stanford University; Stanford University; Stanford Medicine; Institute of Science Tokyo; Tokyo Medical & Dental University (TMDU); Stanford Medicine; Stanford University; Stanford University; Stanford Medicine; Howard Hughes Medical Institute
  摘要：Stem cell-based human embryo models offer a unique opportunity for functional studies of the human-specific features of development. Here we genetically and epigenetically manipulate human blastoids, a 3D embryo model of the blastocyst1, to investigate the functional effect of HERVK LTR5Hs, a hominoid-specific endogenous retrovirus, on pre-implantation development. We uncover a pervasive cis-regulatory contribution of LTR5Hs elements to the hominoid-specific diversification of the epiblast tra...
• Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer AI翻译
  作者：Ireland, Abbie S.; Xie, Daniel A.; Hawgood, Sarah B.; Barbier, Margaret W.; Zuo, Lisa Y.; Hanna, Benjamin E.; Lucas-Randolph, Scarlett; Tyson, Darren R.; Witt, Benjamin L.; Govindan, Ramaswamy; Dowlati, Afshin; Moser, Justin C.; Thomas, Anish; Puri, Sonam; Rudin, Charles M.; Chan, Joseph M.; Elliott, Andrew; Oliver, Trudy G.
  作者单位：Duke University; Utah System of Higher Education; University of Utah; Washington University (WUSTL); Siteman Cancer Center; University System of Ohio; Case Western Reserve University; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); H Lee Moffitt Cancer Center & Research Institute; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center
  摘要：Neuroendocrine and tuft cells are rare chemosensory epithelial lineages defined by the expression of ASCL1 and POU2F3 transcription factors, respectively. Neuroendocrine cancers, including small cell lung cancer (SCLC), frequently display tuft-like subsets, a feature linked to poor patient outcomes1, 2, 3, 4, 5, 6, 7, 8-9. The mechanisms driving neuroendocrine-tuft tumour heterogeneity and the origins of tuft-like cancers are unknown. Using multiple genetically engineered animal models of SCLC...
• A ductile solid electrolyte interphase for solid-state batteries AI翻译
  作者：Mi, Jinshuo; Yang, Jun; Chen, Likun; Cui, Wenting; Li, Yuhang; An, Xufei; Ma, Jiabin; Yang, Ke; Xie, Yaoshu; Biao, Jie; Long, Yu; Ge, Huilin; Han, Bing; Ke, Ruohong; Xiao, Guanyou; Tan, Shendong; Zhang, Danfeng; Cheng, Xing; Hou, Tingzheng; Huang, Yan-Fei; Liu, Ming; Lv, Wei; Gan, Lin; He, Yan-Bing; Yang, Quan-Hong; Kang, Feiyu
  作者单位：Tsinghua University; Tsinghua Shenzhen International Graduate School; Tsinghua University; Tianjin University; Eastern Institute of Technology, Ningbo; Eastern Institute for Advanced Study; Shenzhen University; Nankai University; Haihe Laboratory of Sustainable Chemical Transformations
  摘要：Solid-state lithium metal batteries are facing huge challenges under practical working conditions1,2. Even when the ionic conductivity of composite solid-state electrolytes is increased to 1 mS cm-1, it is still difficult to realize long-life cycling of solid-state batteries above a current density of 1 mA cm-2 and an areal capacity of 1 mAh cm-2 (ref. 3). The fundamental cause is the brittle nature of the solid-electrolyte interphase (SEI) with sluggish lithium-ion transport and the resulting...