8090期

最新文章

• Beyond growth - why we need to agree on an alternative to GDP now AI翻译
  作者：Costanza, Robert; Eastoe, Joseph; Hoekstra, Rutger; Kubiszewski, Ida; O'neill, Daniel W.
  作者单位：University of London; University College London; University of London; University College London; University of Barcelona
• Google DeepMind won a Nobel prize for AI: can it produce the next big breakthrough? AI翻译
  作者：Gibney, Elizabeth
• Gut bacteria help mice to stay lean AI翻译
  作者：[Anonymous]
• The oldest known lepidosaur and origins of lepidosaur feeding adaptations AI翻译
  作者：Marke, Daniel; Whiteside, David I.; Sethapanichsakul, Thitiwoot; Coram, Robert A.; Fernandez, Vincent; Liptak, Alexander; Newham, Elis; Benton, Michael J.
  作者单位：University of Bristol; University of Edinburgh; Natural History Museum London; University of London; University College London; European Synchrotron Radiation Facility (ESRF); Diamond Light Source; University of London; Queen Mary University London; University of London; Queen Mary University London
  摘要：The Lepidosauria is the most species-rich group of land-dwelling vertebrates. The group includes around 12,000 species of lizards and snakes (Squamata) and one species of Rhynchocephalia, the tuatara Sphenodon punctatus from New Zealand1. Squamates owe their success to their generally small size, but also to their highly mobile skull that enables them to manipulate large prey. These key features of lizard and snake skulls are not seen in Sphenodon, which makes it important to understand the na...
• Ribonucleotide incorporation into mitochondrial DNA drives inflammation AI翻译
  作者：Bahat, Amir; Milenkovic, Dusanka; Cors, Eileen; Barnett, Mabel; Niftullayev, Sadig; Katsalifis, Athanasios; Schwill, Marc; Kirschner, Petra; Macvicar, Thomas; Giavalisco, Patrick; Jenninger, Louise; Clausen, Anders R.; Paupe, Vincent; Prudent, Julien; Larsson, Nils-Goran; Rogg, Manuel; Schell, Christoph; Muylaert, Isabella; Lekholm, Erik; Nolte, Hendrik; Falkenberg, Maria; Langer, Thomas
  作者单位：Max Planck Society; University of Gothenburg; University of Cambridge; Karolinska Institutet; University of Freiburg; University of Cologne
  摘要：Metabolic dysregulation can lead to inflammatory responses1,2. Imbalanced nucleotide synthesis triggers the release of mitochondrial DNA (mtDNA) to the cytosol and an innate immune response through cGAS-STING signalling3. However, how nucleotide deficiency drives mtDNA-dependent inflammation has not been elucidated. Here we show that nucleotide imbalance leads to an increased misincorporation of ribonucleotides into mtDNA during age-dependent renal inflammation in a mouse model lacking the mit...
• Fishing around offshore wind farms could boost both conservation and green energy AI翻译
  作者：Claudet, Joachim; Sheehan, Emma V.; Stanley, Ryan R. E.
  作者单位：University of Plymouth; Bedford Institute of Oceanography
• International PhD student numbers in US hold steady - for now AI翻译
  作者：Garisto, Dan
• Lanthanides go electric: promising light emitters used in LEDs AI翻译
  作者：Schuck, P. James
  作者单位：Columbia University
• Volcano mega-eruptions lead to parched times AI翻译
  作者：[Anonymous]
• Isolation, engineering and ecology of temperate phages from the human gut AI翻译
  作者：Dahlman, Sofia; Avellaneda-Franco, Laura; Rutten, Emily L.; Gulliver, Emily L.; Solari, Sean; Chonwerawong, Michelle; Kett, Ciaren; Subedi, Dinesh; Young, Remy B.; Campbell, Nathan; Gould, Jodee A.; Bell, Jasmine D.; Docherty, Callum A. H.; Turkington, Christopher J. R.; Nezam-Abadi, Neda; Grasis, Juris A.; Lyras, Dena; Edwards, Robert A.; Forster, Samuel C.; Barr, Jeremy J.
  作者单位：Monash University; Hudson Institute of Medical Research; Monash University; Monash University; University of New South Wales Sydney; University College Cork; University of California System; University of California Merced; Monash University; Flinders University
  摘要：Large-scale metagenomic and data-mining efforts have revealed an expansive diversity of bacteriophages (phages) within the human gut1, 2-3. However, functional understanding of phage-host interactions within this complex environment is limited, largely due to a lack of cultured isolates available for experimental validation. Here we characterize 134 inducible prophages originating from 252 human gut bacterial isolates using 10 different induction conditions to expand the experimentally validat...