8090期

最新文章

• Electro-generated excitons for tunable lanthanide electroluminescence AI翻译
  作者：Tan, Jing; Zhang, Peng; Song, Xiaoqing; Han, Chunmiao; Wang, Feng; Zhang, Jing; Duan, Chunbo; Zhang, Zhilong; Han, Sanyang; Xu, Hui; Liu, Xiaogang
  作者单位：Heilongjiang University; Heilongjiang University; Tsinghua University; Tsinghua Shenzhen International Graduate School; City University of Hong Kong; South China University of Technology; National University of Singapore; National University of Singapore; National University of Singapore
  摘要：Lanthanide nanocrystals offer unique advantages for electroluminescence (EL) applications, including narrow-band emission, high colour purity and compositionally tunable output(1, 2, 3-4). However, their insulating nature poses a challenge for carrier transport and injection, impeding their application in electrically driven optoelectronic devices(5). Here we demonstrate efficient EL from insulating lanthanide fluoride nanocrystals (4 nm; NaGdF4:X; X = Tb3+, Eu3+ or Nd3+) coated with a series ...
• A conserved H3K14ub-driven H3K9me3 for chromatin compartmentalization AI翻译
  作者：Huang, Yuanyong; Sun, Yimei; Qi, Hongyun; Jiang, Quanlong; Li, Jialun; Chang, Mingzhi; Li, Xinyan; Shu, Lei; Duan, Xiaoya; Wang, Yiqin; Fang, Kailun; Mao, Hailei; Han, Mengmeng; Weng, Yuan; Zhang, Qiao; Chen, Zhaosu; Wei, Wei; Song, Gaojie; Zhang, Qiansen; Li, Jiwen; Han, Jing-Dong J.; Chen, Charlie Degui; Wong, Jiemin
  作者单位：East China Normal University; East China Normal University; East China Normal University; Chinese Academy of Sciences; Center for Excellence in Molecular Cell Science, CAS; Southeast University - China; Peking University
  摘要：Compartmentalization of eukaryotic genome into euchromatin and heterochromatin is of critical biological significance1, 2-3. Previous studies have suggested a self-templating pathway involving the reading and writing of histone H3 lysine 9 methylation by SUV39H as the core mechanism for heterochromatin reassembly during cell division1,3. In fission yeast, the mammalian SUV39H homologue Clr4 forms a complex containing ubiquitin ligase Cul4, which catalyses H3K14 mono-ubiquitination (H3K14ub) to...
• Leaders at COP30 should promote solar and wind power over mega-dams AI翻译
  作者：Yang, Hong; Gao, Xiang; Wu, Jianhua; Thompson, Julian R.
  作者单位：University of Reading; Zhejiang University of Technology; University of London; University College London
• South Africa is right to put debt, climate and inequality at the heart of G20 AI翻译
  作者：[Anonymous]
• Honouring visionary scientist and Nature's founder, Norman Lockyer AI翻译
  作者：[Anonymous]
• The UK must not lose its focus on science and innovation AI翻译
  作者：[Anonymous]
• A parabrachial hub for need-state control of enduring pain AI翻译
  作者：Goldstein, Nitsan; Maes, Amadeus; Allen, Heather N.; Nelson, Tyler S.; Kruger, Kayla A.; Kindel, Morgan; Yeung, Albert T. M.; Smith, Nicholas K.; Carty, Jamie R. E.; Boccia, Lavinia; Blank, Niklas; Lo, Emily; Villari, Rachael E.; Cho, Ella; Marble, Erin L.; Awh, Michelle; Dumiaty, Yasmina; Chee, Melissa J.; Khanna, Rajesh; Thaiss, Christoph A.; Taylor, Bradley K.; Kennedy, Ann; Betley, J. Nicholas
  作者单位：University of Pennsylvania; Scripps Research Institute; State University System of Florida; University of Florida; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Stanford University; Stanford Medicine; Carleton University; University of Pennsylvania; Pennsylvania Medicine; University of Pennsylvania; Pennsylvania Medicine; University of Pennsylvania
  摘要：Long-term sustained pain following acute physical injury is a prominent feature of chronic pain conditions1. Populations of neurons that rapidly respond to noxious stimuli or tissue damage have been identified in the spinal cord and several nuclei in the brain2, 3-4. Understanding the central mechanisms that signal ongoing sustained pain, including after tissue healing, remains a challenge5. Here we use spatial transcriptomics, neural manipulations, activity recordings and computational modell...
• Holliday junction-ZMM protein feedback enables meiotic crossover assurance AI翻译
  作者：Henggeler, Adrian; Orlic, Lucija; Velikov, Daniel; Matos, Joao
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Vienna; Vienna Biocenter (VBC); Medical University of Vienna; Medical University of Vienna
  摘要：Holliday junctions (HJs) are branched four-way DNA structures that link recombining chromosomes during double-strand break repair1. Despite posing a risk to chromosome segregation, HJs accumulate during meiotic prophase I as intermediates in the process of crossing-over2,3. Whether HJs have additional regulatory functions remains unclear. Here we establish an experimental system in budding yeast that enables conditional nucleolytic resolution of HJs after the establishment of meiotic chromosom...
• Treatment made that is effective against a wide range of snake venoms AI翻译
  作者：Khalek, Irene S.; Jardine, Joseph G.
  作者单位：Scripps Research Institute
• 'Google Maps' for Roman roads reveals vast extent of ancient network AI翻译
  作者：Kavanagh, Katie