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作者:Tan, Jing; Zhang, Peng; Song, Xiaoqing; Han, Chunmiao; Wang, Feng; Zhang, Jing; Duan, Chunbo; Zhang, Zhilong; Han, Sanyang; Xu, Hui; Liu, Xiaogang
作者单位:Heilongjiang University; Heilongjiang University; Tsinghua University; Tsinghua Shenzhen International Graduate School; City University of Hong Kong; South China University of Technology; National University of Singapore; National University of Singapore; National University of Singapore
摘要:Lanthanide nanocrystals offer unique advantages for electroluminescence (EL) applications, including narrow-band emission, high colour purity and compositionally tunable output(1, 2, 3-4). However, their insulating nature poses a challenge for carrier transport and injection, impeding their application in electrically driven optoelectronic devices(5). Here we demonstrate efficient EL from insulating lanthanide fluoride nanocrystals (4 nm; NaGdF4:X; X = Tb3+, Eu3+ or Nd3+) coated with a series ...
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作者:Huang, Yuanyong; Sun, Yimei; Qi, Hongyun; Jiang, Quanlong; Li, Jialun; Chang, Mingzhi; Li, Xinyan; Shu, Lei; Duan, Xiaoya; Wang, Yiqin; Fang, Kailun; Mao, Hailei; Han, Mengmeng; Weng, Yuan; Zhang, Qiao; Chen, Zhaosu; Wei, Wei; Song, Gaojie; Zhang, Qiansen; Li, Jiwen; Han, Jing-Dong J.; Chen, Charlie Degui; Wong, Jiemin
作者单位:East China Normal University; East China Normal University; East China Normal University; Chinese Academy of Sciences; Center for Excellence in Molecular Cell Science, CAS; Southeast University - China; Peking University
摘要:Compartmentalization of eukaryotic genome into euchromatin and heterochromatin is of critical biological significance1, 2-3. Previous studies have suggested a self-templating pathway involving the reading and writing of histone H3 lysine 9 methylation by SUV39H as the core mechanism for heterochromatin reassembly during cell division1,3. In fission yeast, the mammalian SUV39H homologue Clr4 forms a complex containing ubiquitin ligase Cul4, which catalyses H3K14 mono-ubiquitination (H3K14ub) to...
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作者:Yang, Hong; Gao, Xiang; Wu, Jianhua; Thompson, Julian R.
作者单位:University of Reading; Zhejiang University of Technology; University of London; University College London
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作者:[Anonymous]
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作者:[Anonymous]
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作者:[Anonymous]
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作者:Goldstein, Nitsan; Maes, Amadeus; Allen, Heather N.; Nelson, Tyler S.; Kruger, Kayla A.; Kindel, Morgan; Yeung, Albert T. M.; Smith, Nicholas K.; Carty, Jamie R. E.; Boccia, Lavinia; Blank, Niklas; Lo, Emily; Villari, Rachael E.; Cho, Ella; Marble, Erin L.; Awh, Michelle; Dumiaty, Yasmina; Chee, Melissa J.; Khanna, Rajesh; Thaiss, Christoph A.; Taylor, Bradley K.; Kennedy, Ann; Betley, J. Nicholas
作者单位:University of Pennsylvania; Scripps Research Institute; State University System of Florida; University of Florida; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Stanford University; Stanford Medicine; Carleton University; University of Pennsylvania; Pennsylvania Medicine; University of Pennsylvania; Pennsylvania Medicine; University of Pennsylvania
摘要:Long-term sustained pain following acute physical injury is a prominent feature of chronic pain conditions1. Populations of neurons that rapidly respond to noxious stimuli or tissue damage have been identified in the spinal cord and several nuclei in the brain2, 3-4. Understanding the central mechanisms that signal ongoing sustained pain, including after tissue healing, remains a challenge5. Here we use spatial transcriptomics, neural manipulations, activity recordings and computational modell...
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作者:Henggeler, Adrian; Orlic, Lucija; Velikov, Daniel; Matos, Joao
作者单位:Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Vienna; Vienna Biocenter (VBC); Medical University of Vienna; Medical University of Vienna
摘要:Holliday junctions (HJs) are branched four-way DNA structures that link recombining chromosomes during double-strand break repair1. Despite posing a risk to chromosome segregation, HJs accumulate during meiotic prophase I as intermediates in the process of crossing-over2,3. Whether HJs have additional regulatory functions remains unclear. Here we establish an experimental system in budding yeast that enables conditional nucleolytic resolution of HJs after the establishment of meiotic chromosom...
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作者:Khalek, Irene S.; Jardine, Joseph G.
作者单位:Scripps Research Institute
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作者:Kavanagh, Katie