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作者：Nordmann, Gregory C.; Balay, Spencer D.; Kapuruge, Thamari N.; Numi, Marco; Leeb, Christoph; Nimpf, Simon; Malkemper, E. Pascal; Landler, Lukas; Keays, David A.
作者单位：University of Munich; University of Vienna; Medical University of Vienna; BOKU University; University of Cambridge; Vienna Biocenter (VBC); Research Institute of Molecular Pathology (IMP)
摘要：How animals detect Earth's magnetic field remains a mystery in sensory biology. Despite extensive behavioral evidence, the neural circuitry and molecular mechanisms responsible for magnetic sensing remain elusive. Adopting an unbiased approach, we used whole-brain activity mapping, tissue clearing, and light sheet microscopy to identify neuronal populations activated by magnetic stimuli in the pigeon (Columba livia). We demonstrate robust, light-independent bilateral neuronal activation in the...
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作者：Mazelis, Ignas; Sun, Haoxiang; Kulkarni, Arpita; Torre, Theresa L.; Klein, Allon M.
作者单位：Harvard University; Harvard Medical School; Harvard University; Harvard Medical School
摘要：Single-cell sequencing methods uncover natural and induced variation between cells. Many functional genomic methods, however, require multiple steps that cannot yet be scaled to high throughput, including assays on living cells. In this study, we developed capsules with amphiphilic gel envelopes (CAGEs), which selectively retain cells and large analytes while being freely accessible to media, enzymes, and reagents. Capsules enable high-throughput multistep assays combining live-cell culture wi...
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作者：Anstett, Daniel N.; Anstett, Julia; Sheth, Seema N.; Moxley, Dylan R.; Branch, Haley A.; Jahani, Mojtaba; Huang, Kaichi; Todesco, Marco; Jordan, Rebecca; Lazaro-Guevara, Jose Miguel; Rieseberg, Loren H.; Angert, Amy L.
作者单位：University of British Columbia; University of British Columbia; Cornell University; Cornell University; Michigan State University; Michigan State University; Michigan State University; University of British Columbia; University of British Columbia; North Carolina State University; University of British Columbia; Yale University; Sun Yat Sen University; University of British Columbia; University of British Columbia Okanagan; Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Environment; McGill University; McGill University; University of British Columbia
摘要：Populations that are declining as a result of climate change may need to evolve to persist. Although evolutionary rescue has been demonstrated in theory and in the laboratory, its relevance to natural populations facing climate change remains unknown. Here we link rapid evolution and population dynamics in scarlet monkeyflower, Mimulus cardinalis, during exceptional drought. We leverage whole-genome sequencing across 55 populations to identify climate-associated loci. Simultaneously we track d...
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作者：Dogra-Freitag, Aashima
