6787期

最新文章

• Implanted flexible electronics reveal principles of human islet cell electrical maturation AI翻译
  作者：Li, Qiang; Liu, Ren; Lin, Zuwan; Zhang, Xinhe; Wang, Wenbo; Galicia-Silva, Israeli M.; Liu, Mai; Gao, Zihan; Pollock, Samuel D.; Alvarez-Dominguez, Juan R.; Liu, Jia
  作者单位：Harvard University; Harvard University; University of Pennsylvania; Pennsylvania Medicine; University of Pennsylvania; Pennsylvania Medicine; University of Pennsylvania; Pennsylvania Medicine; University of Pennsylvania; Howard Hughes Medical Institute; Pennsylvania Medicine
  摘要：Understanding how human pancreatic alpha and beta cell electrical activities mature is critical for building fully functional stem cell-derived (SC-) pancreatic organoids for research and therapeutics. We implanted tissue-like, stretchable electronics during organogenesis of human pancreatic organoids, enabling months-long, single cell-resolved electrophysiology. Longitudinal single-cell tracking suggested that improved hormone responsiveness reflects increasing activity of SC-alpha and -beta ...
• Matching sounds to shapes: Evidence of the bouba-kiki effect in naïve baby chicks AI翻译
  作者：Loconsole, Maria; Benavides-Varela, Silvia; Regolin, Lucia
  作者单位：University of Padua; University of Padua; University of Padua
  摘要：Humans across multiple languages spontaneously associate the nonwords kiki and bouba with spiky and round shapes, respectively, a phenomenon named the bouba-kiki effect. To explore the origin of this association, and whether it is unique to humans, we tested the bouba-kiki effect in baby domestic chickens (Gallus gallus). As a precocial species, chicks can be tested shortly after hatching, allowing us to control their pretest experiences. Similar to humans, both 3-day-old [Experiment 1 (Exp. 1...
• The science and practice of proportionality in AI risk evaluations AI翻译
  作者：Mougan, Carlos; Morlock, Lauritz; Aguirre, Jair; Black, James R. M.; Brauner, Jan; Campos, Simeon; Dev, Sunishchal; Llorca, David Fernandez; Franzin, Alberto; Fritz, Mario; Gomez, Emilia; Grosse-Holz, Friederike; Hamilton, Eloise; Hasin, Max; Hernandez-Orallo, Jose; Lahav, Dan; Massarelli, Luca; Mavroudis, Vasilios; Murray, Malcolm; Paskov, Patricia; Raldua, Jaime; Schellaert, Wout
  作者单位：RAND Corporation; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Universitat Politecnica de Valencia; University of Cambridge; Alan Turing Institute
• A whole-brain single-cell atlas of circadian neural activity in mice AI翻译
  作者：Yamashita, Katsunari; Kinoshita, Fukuaki L.; Yoshida, Shota Y.; Matsumoto, Katsuhiko; Mitani, Tomoki T.; Fujishima, Hiroshi; Minami, Yoichi; Morii, Eiichi; Yamada, Rikuhiro G.; Okada, Seiji; Ueda, Hiroki R.
  作者单位：RIKEN; University of Tokyo; University of Osaka; University of Osaka; University of Osaka; University of Osaka; University of Tokyo; Niigata University; Kurume University
  摘要：The mammalian brain comprises numerous anatomical regions with distinct functions despite their extensive connectivity. How spontaneous neural activity is coordinated across regions over the circadian cycle remains elusive. We used tissue clearing and whole-brain c-Fos immunostaining on 144 mouse brains collected over 2 days under constant darkness. Time-series analysis revealed brainwide circadian rhythmicity at single-cell resolution, with 79% of the 642 anatomically defined regions oscillat...
• Deciphering D AI翻译
  作者：Cohen, Jon
  作者单位：Universidad Autonoma de Nuevo Leon
• Black holes disguised as little red dots AI翻译
  作者：Matthee, Jorryt
  作者单位：Institute of Science & Technology - Austria