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作者：Chen, Ningyuan; Khademi, Amin
作者单位：University of Toronto; Clemson University
摘要：Problem definition: We study early-stage dose-finding clinical trials with simultaneous consideration of efficacy and toxicity without parametric assumptions on the forms of the unknown dose-efficacy and dose-toxicity curves. We propose algorithms that adaptively allocate doses based on patient responses, in order to maximize the efficacy for the patients during the trial while minimizing the toxicity. Methodology/results: We leverage online learning to design the clinical trial and propose tw...
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作者：Zhong, Zhiheng; Cao, Ping; Huang, Junfei; Zhou, Sean X.
作者单位：South China University of Technology; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese University of Hong Kong
摘要：Problem definition: This paper considers a tandem queueing system in which stage 1 has one station serving multiple classes of arriving customers with different service requirements and related delay costs, and stage 2 has multiple parallel stations, with each station providing one type of service. Each station has many statistically identical servers. The objective is to design a joint capacity allocation between stages/stations and scheduling rule of different classes of customers to minimiz...
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作者：Webster, Scott; Kazaz, Burak; Gheibi, Shahryar
作者单位：Arizona State University; Arizona State University-Tempe; Syracuse University
摘要：Problem definition : Leading specialty coffee roasters rely on direct trade to source premium coffee beans. We examine a roaster who sells two basic types of roasts: (1) a single-origin roast sourced from a specific locale and (2) a blend roast that uses a mix of beans from sources that vary over the course of a year. The prices of blend roasts are lower than those of single-origin roasts and appeal to a larger market. We study how characteristics of the operating and market environment affect...
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作者：Kadiyala, Bharadwaj; Ozer, Ozalp; Simsek, A. Serdar
作者单位：Utah System of Higher Education; University of Utah; Amazon.com; University of Texas System; University of Texas Dallas
摘要：Problem definition: : Gift card promotions offer a tiered incentive (a gift card) to customers for purchasing regularly -priced products, with higher expenditure receiving a larger incentive. We empirically investigate the impact of gift card promotions on customer purchase behavior by collaborating with a major U.S.-based department store that targets gift card promotion emails on its online channel. Methodology/results: : We use a collection of discontinuities in the retailer's targeting pol...
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作者：Wei, Wei; Arora, Priyank; Solak, Senay
作者单位：University System Of New Hampshire; University of New Hampshire; University of South Carolina System; University of South Carolina Columbia; University of Massachusetts System; University of Massachusetts Amherst
摘要：Problem definition: : Most subsidy welfare programs operate in a bilevel hierarchical structure, wherein a funding agency allocates funds to multiple service organizations. . These service organizations invest in activities within their areas to generate societal impact for beneficiaries by enhancing the quantity and quality of services at local providers. The funds allocation decisions in such programs are complicated by the funding agency's equity consideration, intricate relationships among...
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作者：Zeng, Jacob Z.; Agarwal, Ashish; Stamatopoulos, Ioannis
作者单位：Gonzaga University; University of Texas System; University of Texas Austin
摘要：Problem definition: : Despite their widespread use, promotional inventory displays' campaign execution is opaque. Brands (manufacturers) can only verify in-store display presence through manual, on -site audits, which are costly and limited in scope. This lack of visibility into execution makes it difficult for brands to quantify the sales impact of displays and properly evaluate campaign performance. Methodology/results: : We use Internet -of -Things (IoT)-generated data on the real-time loca...
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作者：Wu, Chao; Eftekhar, Mahyar
作者单位：Wayne State University; Arizona State University; Arizona State University-Tempe
摘要：Problem definition: : Conventional wisdom often cautions charities against providing volunteer opportunities to potential donors based on the assumption that volunteering crowds out monetary donations. We challenge this assumption and investigate the causal relationship between an individual's volunteering activities and their subsequent decisions to donate. Methodology/results: : We conducted three consequential experiments where participants engaged in virtual assignments and were subsequent...
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作者：Li, Xiaobo; Lin, Hongyuan; Liu, Fang
作者单位：National University of Singapore; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Durham University
摘要：Problem definition: This paper studies the single-warehouse assortment selection problem that aims to minimize the order fulfillment cost under the cardinality constraint. We propose two fulfillment-related cost functions corresponding to spillover fulfillment and order splitting. This problem includes the fill rate maximization problem as a special case. We show that although the objective function is submodular for a broad class of cost functions, the fill rate maximization problem with the ...
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作者：Lei, Dazhou; Qi, Yongzhi; Liu, Sheng; Geng, Dongyang; Zhang, Jianshen; Hu, Hao; Shen, Zuo-Jun Max
作者单位：Beijing Jiaotong University; University of Toronto; University of Hong Kong
摘要：Problem definition : How should retailers leverage aggregate (category) sales information for individual product demand prediction? Motivated by inventory risk pooling, we develop a new prediction framework that integrates category-product sales information to exploit the benefit of pooling. Methodology/results : We propose to combine data from different aggregation levels in a transfer learning framework. Our approach treats the top -level sales information as a regularization for fitting the...
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作者：Lobel, Ilan; Martin, Sebastien; Song, Haotian
作者单位：New York University; Northwestern University; Zhejiang University
摘要：Problem definition: : We consider a platform's problem of how to staff its operations given the possibilities of hiring employees and setting up a contractor marketplace. We aim to understand the operational difference between these two work arrangement models. Methodology/results: : We consider a model where demand is not only stochastic but also evolving over time, which we capture via a state of the world that determines the demand distribution. In the case of employees, the platform contro...
