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作者：Olivier, Charlotte-Anais; Martin, Jordan S.; Pilisi, Camille; Agnani, Paul; Kauffmann, Cecile; Hayes, Loren; Jaeggi, Adrian V.; Schradin, C.
作者单位：Universites de Strasbourg Etablissements Associes; Universite de Strasbourg; Centre National de la Recherche Scientifique (CNRS); University of Witwatersrand; University of Zurich; University of Tennessee System; University of Tennessee at Chattanooga
摘要：Explaining the evolution of primate social organization has been fundamental to under-stand human sociality and social evolution more broadly. It has often been suggested that the ancestor of all primates was solitary and that other forms of social organization evolved later, with transitions being driven by various life history traits and ecologi-cal factors. However, recent research showed that many understudied primate species previously assumed to be solitary actually live in pairs, and in...
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作者：Qiu, Caihao; Salvalaglio, Marco; Srolovitz, David J.; Han, Jian
作者单位：City University of Hong Kong; Technische Universitat Dresden; Technische Universitat Dresden; University of Hong Kong
摘要：Grain rotation is commonly observed during the evolution of microstructures in polycrystalline materials of different kinds, including metals, ceramics, and colloidal crystals. It is widely accepted that interface migration in these systems is mediated by the motion of line defects with step and dislocation character, i.e., disconnections. We propose a crystallography-respecting continuum model for arbitrarily curved grain boundaries or heterophase interfaces, accounting for the disconnections...
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作者：Hartmann, Jakob; Klengel, Claudia; Dillmann, Larissa J.; Hisey, Erin E.; Hafner, Kathrin; Shukla, Rammohan; Estruch, Marina Soliva; Bajaj, Thomas; Ebert, Tim; Mabbott, Katharine G.; Rostin, Luise; Philipsen, Alexandra; Carlezon Jr, William A.; Gisabella, Barbara; Mccullumsmith, Robert E.; Vergis, John M.; Klengel, Torsten; Daskalakis, Nikolaos P.; Pantazopoulos, Harry; Gassen, Nils C.; Ressler, Kerry J.
作者单位：Harvard University; Harvard University Medical Affiliates; McLean Hospital; Max Planck Society; University of Wyoming; University of Bonn; University of Mississippi Medical Center; University of Mississippi; University System of Ohio; University of Toledo
摘要：Genes involved in regulating the hypothalamic-pituitary-adrenal (HPA) axis, including the glucocorticoid receptor (GR), are linked to various stress- related psychopathologies including bipolar disorder as well as other mood and trauma- related disorders. The protein product of the cell cycle gene, SKA2, is a GR interaction partner in peripheral cells. However, the precise roles of SKA2 in stress and GR signaling in the brain, specifically in nonreplicating postmitotic neurons, and its involve...
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作者：Hata, Masayuki; Hata, Maki; Dejda, Agnieszka; Pilon, Frederique; Diaz-Marin, Roberto; Fournier, Frederik; Joyal, Jean- Sebastien; Cagnone, Gael; Ochi, Yotaro; Crespo-Garcia, Sergio; Wilson, Ariel M.; Sapieha, Przemyslaw
作者单位：Universite de Montreal; Universite de Montreal; Kyoto University
摘要：Tissue inflammation is often broadly associated with cellular damage, yet sterile inflammation also plays critical roles in beneficial tissue remodeling. In the central nervous system, this is observed through a predominantly innate immune response in retinal vascular diseases such as age- related macular degeneration, diabetic retinopathy, and retinopathy of prematurity. Here, we set out to elucidate the dynamics of the immune response during progression and regression of pathological neovasc...
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作者：Purnomo, Gludhug A.; Kealy, Shimona; O'Connor, Sue; Schapper, Antoinette; Shaw, Ben; Llamas, Bastien; Teixeira, Joao C.; Sudoyo, Herawati; Tobler, Raymond
作者单位：University of Adelaide; University of Adelaide; Australian National University; Australian National University; Vrije Universiteit Amsterdam; Centre National de la Recherche Scientifique (CNRS); Australian National University; Australian National University; John Curtin School of Medical Research; The Kids Research Institute Australia; Universidade de Coimbra
摘要：The tropical archipelago of Wallacea was first settled by anatomically modern humans (AMH) by 50 thousand years ago (kya), with descendent populations thought to have remained genetically isolated prior to the arrival of Austronesian seafarers around 3.5 kya. Modern Wallaceans exhibit a longitudinal countergradient of Papuan- and Asian- related ancestries widely considered as evidence for mixing between local populations and Austronesian seafarers, though converging multidisciplinary evidence ...
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作者：Warnberg, Emil; Kumar, Arvind
作者单位：Karolinska Institutet; Royal Institute of Technology
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作者：Luo, Hui; Xuan, Hongli; Wang, Dong; Du, Ziwan; Li, Zhongyang; Bu, Kejun; Guo, Songhao; Mao, Yuhong; Lan, Fujun; Liu, Fuyang; Yin, Yanfeng; Tian, Wenming; Hu, Qingyang; Liu, Gang; Liu, Haozhe; Zeng, Qiaoshi; Ding, Yang; Fu, Yongping; Li, Qian; Jin, Shengye; Yang, Wenge; Mao, Ho - Kwang; Lu, Xujie
作者单位：Tsinghua University; Chinese Academy of Sciences; Dalian Institute of Chemical Physics, CAS; Chinese Academy of Sciences; Dalian Institute of Chemical Physics, CAS; Chinese Academy of Sciences; Peking University
摘要：High pressure can create extreme conditions that enable the formation of novel materials and the discovery of new phenomena. However, the ability to preserve the desirable characteristics of materials obtained under high pressure has remained an elusive challenge, as the pressure- induced changes are typically reversible, except for the pressure- induced chemical reactions such as polymerization of hydrocarbons. Here, we propose the concept of pressure aging (PA) that enables the permanent loc...
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作者：Seligman, Darryl Z.; Farnocchia, Davide; Micheli, Marco; Hainaut, Olivier R.; Hsieh, Henry H.; Feinstein, Adina D.; Chesley, Steven R.; Taylor, Aster G.; Masiero, Joseph; Meech, Karen J.
作者单位：Michigan State University; Cornell University; Cornell University; California Institute of Technology; National Aeronautics & Space Administration (NASA); NASA Jet Propulsion Laboratory (JPL); European Space Agency; European Southern Observatory; University of Colorado System; University of Colorado Boulder; University of Michigan System; University of Michigan; California Institute of Technology; University of Hawaii System
摘要：Small bodies are capable of delivering essential prerequisites for the development of life, such as volatiles and organics, to the terrestrial planets. For example, empirical evidence suggests that water was delivered to the Earth by hydrated planetesimals from distant regions of the Solar System . Recently, several morphologically inactive near- Earth objects were reported to experience significant nongravitational accelerations inconsistent with radiation-based effects, and possibly explaine...
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作者：Iu, David S.; Maya, Jessica; Vu, Luyen T.; Fogarty, Elizabeth A.; Mcnairn, Adrian J.; Ahmed, Faraz; Franconi, Carl J.; Munn, Paul R.; Grenier, Jennifer K.; Hanson, Maureen R.; Grimson, Andrew
作者单位：Cornell University; Cornell University; Cornell University
摘要：Myalgic encephalomyelitis/chronic fatigue syndrome (ME) is a severe, debilitating disease, with substantial evidence pointing to immune dysregulation as a key contributor to pathophysiology. To characterize the gene regulatory state underlying T cell dysregulation in ME, we performed multiomic analysis across T cell subsets by integrating single- cell RNA-seq, RNA-seq, and ATAC-seq and further analyzed CD8+ T cell subpopulations following symptom provocation. Specific subsets of CD8+ T cells, ...
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作者：Jahn, Steffen; Guhl, Daniel; Erhard, Ainslee
作者单位：Martin Luther University Halle Wittenberg; Humboldt University of Berlin; University of Gottingen
摘要：Efforts to promote sustainable resource use through reduced meat consumption face challenges as global meat consumption persists. The resistance may be attributed to the lower sales price of meat compared to most plant- based meat alternatives (PBMAs). Addressing this, our research delves into the pivotal question of which PBMAs resonate most with consumers and how pricing affects demand. In a hypothetical restaurant context, we conducted 2 representative studies among 2,126 individuals in the...
