作者:Keasler, Kaitlyn T.; Zick, Mary E.; Stacy, Emily E.; Kim, Jaehwan; Lee, Jung-Hoon; Aeindartehran, Lida; Runcevski, Tomce; Milner, Phillip J.
作者单位:Cornell University; Korea Institute of Science & Technology (KIST); Southern Methodist University
摘要:Fluorine is an increasingly common substituent in pharmaceuticals and agrochemicals because it improves the bioavailability and metabolic stability of organic molecules. Fluorinated gases represent intuitive building blocks for the late-stage installation of fluorinated groups, but they are generally overlooked because they require the use of specialized equipment. We report a general strategy for handling fluorinated gases as benchtop-stable solid reagents using metal-organic frameworks (MOFs...
作者:Satyaki, P. R. V.
作者单位:University of Toronto; University Toronto Scarborough
作者:Goldman, Michael A.
作者单位:California State University System; San Francisco State University
摘要:Distrust and xenophobia have long been stumbling blocks during public health crises Distrust and xenophobia have long been stumbling blocks during public health crises
作者:Bruening, Jens C.; Fenselau, Henning
作者单位:University of Cologne; University of Cologne; University of Cologne; German Center for Diabetes Research (DZD)
摘要:Systemic metabolism has to be constantly adjusted to the variance of food intake and even be prepared for anticipated changes in nutrient availability. Therefore, the brain integrates multiple homeostatic signals with numerous cues that predict future deviations in energy supply. Recently, our understanding of the neural pathways underlying these regulatory principles-as well as their convergence in the hypothalamus as the key coordinator of food intake, energy expenditure, and glucose metabol...