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作者:Wang, Yuzhou; Apte, Joshua S.; Hill, Jason D.; Ivey, Cesunica E.; Johnson, Dana; Min, Esther; Morello-Frosch, Rachel; Patterson, Regan; Robinson, Allen L.; Tessum, Christopher W.; Marshall, Julian D.
作者单位:University of Washington; University of Washington Seattle; University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of Minnesota System; University of Minnesota Twin Cities; University of California System; University of California Berkeley; University of California System; University of California Los Angeles; Carnegie Mellon University; University of Illinois System; University of Illinois Urbana-Champaign
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作者:Abel, Tom
作者单位:Stanford University; Stanford University; United States Department of Energy (DOE); SLAC National Accelerator Laboratory
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作者:Timko, Brian P.
作者单位:Tufts University
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作者:Brainard, Jeffrey
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作者:Daskalova, Gergana N.; Kamp, Johannes
作者单位:International Institute for Applied Systems Analysis (IIASA); University of Gottingen
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作者:Scheringer, Martin
作者单位:Masaryk University; Swiss Federal Institutes of Technology Domain; ETH Zurich
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作者:Fuentes, Agustin
作者单位:Princeton University
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作者:Chang, Chang-Yu; Bajic, Djordje; Vila, Jean C. C.; Estrela, Sylvie; Sanchez, Alvaro
作者单位:Yale University; Yale University; University of Pennsylvania; Delft University of Technology; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Centro Nacional de Biotecnologia (CNB); Stanford University
摘要:Understanding the mechanisms that maintain microbial biodiversity is a critical aspiration in ecology. Past work on microbial coexistence has largely focused on species pairs, but it is unclear whether pairwise coexistence in isolation is required for coexistence in a multispecies community. To address this question, we conducted hundreds of pairwise competition experiments among the stably coexisting members of 12 different enrichment communities in vitro. To determine the outcomes of these e...
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作者:Kun, Eucharist; Javan, Emily M.; Smith, Olivia; Gulamali, Faris; de la Fuente, Javier; Flynn, Brianna I.; Vajrala, Kushal; Trutner, Zoe; Jayakumar, Prakash; Tucker-Drob, Elliot M.; Sohail, Mashaal; Singh, Tarjinder; Narasimhan, Vagheesh M.
作者单位:University of Texas System; University of Texas Austin; Icahn School of Medicine at Mount Sinai; University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin; Universidad Nacional Autonoma de Mexico; NewYork-Presbyterian Hospital; Columbia University; Columbia University; University of Texas System; University of Texas Austin
摘要:The human skeletal form underlies bipedalism, but the genetic basis of skeletal proportions (SPs) is not well characterized. We applied deep-learning models to 31,221 x-rays from the UK Biobank to extract a comprehensive set of SPs, which were associated with 145 independent loci genome-wide. Structural equation modeling suggested that limb proportions exhibited strong genetic sharing but were independent of width and torso proportions. Polygenic score analysis identified specific associations...
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作者:Davis, Harvey; Attwell, David
作者单位:University of London; University College London