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作者:Brainard, Jeffrey
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作者:Brainard, Jeffrey
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作者:Jaycox, Jillian R.; Dai, Yile; Ring, Aaron M.
作者单位:Yale University; Fred Hutchinson Cancer Center
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作者:Kimbis, Thomas P.
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作者:Clery, Daniel
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作者:Wickman, Jonas; Litchman, Elena; Klausmeier, Christopher A.
作者单位:Michigan State University; Michigan State University; Carnegie Institution for Science; Michigan State University; Michigan State University
摘要:Macroecological scaling patterns, such as between prey and predator biomass, are fundamental to our understanding of the rules of biological organization and ecosystem functioning. Although these scaling patterns are ubiquitous, how they arise is poorly understood. To explain these patterns, we used an eco-evolutionary predator-prey model parameterized using data for phytoplankton and zooplankton. We show that allometric scaling relationships at lower levels of biological organization, such as...
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作者:Brainard, Jeffrey
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作者:Siliciano, Janet D.; Siliciano, Robert F.
作者单位:Johns Hopkins University; Johns Hopkins University; Howard Hughes Medical Institute
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作者:Arnoult, Nausica; Cech, Thomas R.
作者单位:University of Colorado System; University of Colorado Boulder; University of Colorado System; University of Colorado Boulder; University of Colorado System; University of Colorado Boulder
摘要:Cells must distinguish between broken chromosome ends and natural ends, or telomeres. Broken chromosomes require repair, but telomeres need to be protected from repair because joining two telomeres would result in disastrous chromosome fusions. Telomerase is the enzyme that maintains chromosome ends by adding repeated DNA sequences. If directed to a DNA break, telomerase would erroneously create a new telomere, precipitating the loss of essential genetic material distal from the break site. Al...
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作者:Brainard, Jeffrey