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作者：Letessier, Tom B.; Mouillot, David; Mannocci, Laura; Jabour Christ, Hanna; Elamin, Elamin Mohammed; Elamin, Sheikheldin Mohamed; Friedlander, Alan M.; Hearn, Alex; Juhel, Jean-Baptiste; Kleiven, Alf Ring; Moland, Even; Mouquet, Nicolas; Nillos-Kleiven, Portia Joy; Sala, Enric; Thompson, Christopher D. H.; Velez, Laure; Vigliola, Laurent; Meeuwig, Jessica J.
作者单位：Zoological Society of London; University of Western Australia; Institut de Recherche pour le Developpement (IRD); Ifremer; Centre National de la Recherche Scientifique (CNRS); Universite de Montpellier; National Geographic Society; University of Hawaii System; University of Hawaii Manoa; Universidad San Francisco de Quito; Institut de Recherche pour le Developpement (IRD); Universite de Montpellier; Ifremer; Institute of Marine Research - Norway; University of Agder; University of Western Australia
摘要：Animal body-size variation influences multiple processes in marine ecosystems, but habitat heterogeneity has prevented a comprehensive assessment of size across pelagic (midwater) and benthic (seabed) systems along anthropic gradients. In this work, we derive fish size indicators from 17,411 stereo baited-video deployments to test for differences between pelagic and benthic responses to remoteness from human pressures and effectiveness of marine protected areas (MPAs). From records of 823,849 ...
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作者：Choquet, Daniel
作者单位：Universite de Bordeaux; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); Universite de Bordeaux
摘要：The mode of action of a synaptic protein is challenged The synaptic Ras/Rap guanosine triphosphatase (GTPase)-activating protein (SynGAP) plays substantial, albeit still elusive, roles in synaptic function (1). SynGAP has attracted considerable attention owing to its pivotal role in modulating excitatory glutamatergic synaptic transmission and neuronal development and because loss-of-function mutations in the SYNGAP1 gene account for up to 1% of genetically based intellectual disabilities. Syn...
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作者：Dudok, Barna; Fan, Linlin Z.; Farrell, Jordan S.; Malhotra, Shreya; Homidan, Jesslyn; Kim, Doo Kyung; Wenardy, Celestine; Ramakrishnan, Charu; Li, Yulong; Deisseroth, Karl; Soltesz, Ivan
作者单位：Baylor College of Medicine; Baylor College of Medicine; Stanford University; Stanford University; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard Medical School; Stanford University; Peking University; Stanford University; Howard Hughes Medical Institute
摘要：Endocannabinoid (eCB)-mediated suppression of inhibitory synapses has been hypothesized, but this has not yet been demonstrated to occur in vivo because of the difficulty in tracking eCB dynamics and synaptic plasticity during behavior. In mice navigating a linear track, we observed location-specific eCB signaling in hippocampal CA1 place cells, and this was detected both in the postsynaptic membrane and the presynaptic inhibitory axons. All-optical in vivo investigation of synaptic responses ...
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作者：Kuang, Xingxing; Liu, Junguo; Scanlon, Bridget R.; Jiao, Jiu Jimmy; Jasechko, Scott; Lancia, Michele; Biskaborn, Boris K.; Wada, Yoshihide; Li, Hailong; Zeng, Zhenzhong; Guo, Zhilin; Yao, Yingying; Gleeson, Tom; Nicot, Jean-Philippe; Luo, Xin; Zou, Yiguang; Zheng, Chunmiao
作者单位：Southern University of Science & Technology; North China University of Water Resources & Electric Power; University of Texas System; University of Texas Austin; University of Hong Kong; University of California System; University of California Santa Barbara; Helmholtz Association; Alfred Wegener Institute, Helmholtz Centre for Polar & Marine Research; King Abdullah University of Science & Technology; Xi'an Jiaotong University; University of Victoria; Eastern Institute of Technology, Ningbo; Eastern Institute for Advanced Study
摘要：In recent decades, climate change and other anthropogenic activities have substantially affected groundwater systems worldwide. These impacts include changes in groundwater recharge, discharge, flow, storage, and distribution. Climate-induced shifts are evident in altered recharge rates, greater groundwater contribution to streamflow in glacierized catchments, and enhanced groundwater flow in permafrost areas. Direct anthropogenic changes include groundwater withdrawal and injection, regional ...
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作者：Shaughnessy, Kevin H.
作者单位：University of Alabama System; University of Alabama Tuscaloosa
摘要：A catalyst system diverts traditional C-C bond coupling into desired C-N bond formation Transition metal-catalyzed cross-coupling, which creates a bond between two target molecules, is a workhorse method for synthesizing pharmaceuticals, agricultural chemicals, electronic materials, and other fine chemicals ( 1 ). The generation of biaryl compounds by the Suzuki-Miyaura (SM) coupling ( 2 ) and of aryl amines by the Buchwald-Hartwig (BH) coupling ( 3 ) reactions are two of the most used transfo...
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作者：Zeng, Lei; Cheng, Kang; Sun, Fanfei; Fan, Qiyuan; Li, Laiyang; Zhang, Qinghong; Wei, Yao; Zhou, Wei; Kang, Jincan; Zhang, Qiuyue; Chen, Mingshu; Liu, Qiunan; Zhang, Liqiang; Huang, Jianyu; Cheng, Jun; Jiang, Zheng; Fu, Gang; Wang, Ye
作者单位：Xiamen University; Chinese Academy of Sciences; Shanghai Institute of Applied Physics, CAS; Shanxi University; Yanshan University
摘要：Maintaining the stability of single-atom catalysts in high-temperature reactions remains extremely challenging because of the migration of metal atoms under these conditions. We present a strategy for designing stable single-atom catalysts by harnessing a second metal to anchor the noble metal atom inside zeolite channels. A single-atom rhodium-indium cluster catalyst is formed inside zeolite silicalite-1 through in situ migration of indium during alkane dehydrogenation. This catalyst demonstr...
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作者：Brainard, Jeffrey
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作者：Di Terlizzi, I.; Gironella, M.; Herraez-Aguilar, D.; Betz, T.; Monroy, F.; Baiesi, M.; Ritort, F.
作者单位：Max Planck Society; University of Padua; University of Barcelona; University of Gothenburg; Universidad Francisco de Vitoria; University of Gottingen; University of Gottingen; Complutense University of Madrid; Istituto Nazionale di Fisica Nucleare (INFN); University of Barcelona
摘要：Entropy production is the hallmark of nonequilibrium physics, quantifying irreversibility, dissipation, and the efficiency of energy transduction processes. Despite many efforts, its measurement at the nanoscale remains challenging. We introduce a variance sum rule (VSR) for displacement and force variances that permits us to measure the entropy production rate sigma in nonequilibrium steady states. We first illustrate it for directly measurable forces, such as an active Brownian particle in a...
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作者：Zhu, Shiwei; Bradfield, Clinton J.; Maminska, Agnieszka; Park, Eui-Soon; Kim, Bae-Hoon; Kumar, Pradeep; Huang, Shuai; Kim, Minjeong; Zhang, Yongdeng; Bewersdorf, Joerg; MacMicking, John D.
作者单位：Howard Hughes Medical Institute; Yale University; Yale University; Yale University; Yale University; Yale University
摘要：INTRODUCTION The compartmentalized landscape of eukaryotic cells offers a wide variety of intracellular niches for microbial pathogens to hide and replicate. Consequently, eukaryotes have evolved compartment-specific immune surveillance mechanisms that alert the host to infection and recruit antimicrobial proteins that help bring microbial replication under control. Many of these host defense proteins form giant macromolecular complexes when encountering either pathogens or their products to a...
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作者：Wadman, Meredith
摘要：Scientists fear wider research impacts if other states label frozen embryos children
