6718期

最新文章

• Somatic mosaicism in schizophrenia brains reveals prenatal mutational processes AI翻译
  作者：Maury, Eduardo A.; Jones, Attila; Seplyarskiy, Vladimir; Nguyen, Thanh Thanh L.; Rosenbluh, Chaggai; Bae, Taejong; Wang, Yifan; Abyzov, Alexej; Khoshkhoo, Sattar; Chahine, Yasmine; Zhao, Sijing; Venkatesh, Sanan; Root, Elise; Voloudakis, Georgios; Roussos, Panagiotis; Park, Peter J.; Akbarian, Schahram; Brennand, Kristen; Reilly, Steven; Lee, Eunjung A.; Sunyaev, Shamil R.; Walsh, Christopher A.; Chess, Andrew
  作者单位：Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard Medical School; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard Medical School; Yale University; Yale University; Mayo Clinic; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Harvard University; Harvard Medical School; Howard Hughes Medical Institute; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital
  摘要：Germline mutations modulate the risk of developing schizophrenia (SCZ). Much less is known about the role of mosaic somatic mutations in the context of SCZ. Deep (239x) whole-genome sequencing (WGS) of brain neurons from 61 SCZ cases and 25 controls postmortem identified mutations occurring during prenatal neurogenesis. SCZ cases showed increased somatic variants in open chromatin, with increased mosaic CpG transversions (CpG>GpG) and T>G mutations at transcription factor binding sites (TFBSs)...
• Science in a shifting policy system AI翻译
  作者：Harris, Theresa; Alexander, Rashada
• Physics award honors pioneers in artificial intelligence AI翻译
  作者：Cho, Adrian
  摘要：Models based in statistical physics led to today's neural networks that power chatbots and self-driving cars
• The Poland experiment AI翻译
  作者：Cyphert, Erika
  作者单位：University of California System; University of California San Diego
• Long-term stability in perovskite solar cells through atomic layer deposition of tin oxide AI翻译
  作者：Gao, Danpeng; Li, Bo; Liu, Qi; Zhang, Chunlei; Yu, Zexin; Li, Shuai; Gong, Jianqiu; Qian, Liangchen; Vanin, Francesco; Schutt, Kelly; Davis, Melissa A.; Palmstrom, Axel F.; Harvey, Steven P.; Long, Nicholas J.; Luther, Joseph M.; Zeng, Xiao Cheng; Zhu, Zonglong
  作者单位：City University of Hong Kong; City University of Hong Kong; Imperial College London; United States Department of Energy (DOE); National Renewable Energy Laboratory - USA; City University of Hong Kong
  摘要：Robust contact schemes that boost stability and simplify the production process are needed for perovskite solar cells (PSCs). We codeposited perovskite and hole-selective contact while protecting the perovskite to enable deposition of SnOx/Ag without the use of a fullerene. The SnOx, prepared through atomic layer deposition, serves as a durable inorganic electron transport layer. Tailoring the oxygen vacancy defects in the SnOx layer led to power conversion efficiencies (PCEs) of >25%. Our dev...
• Tiny comets under the sea AI翻译
  作者：Cael, B. B.; Guidi, Lionel
  作者单位：NERC National Oceanography Centre; Sorbonne Universite; Centre National de la Recherche Scientifique (CNRS)
• Ecological speciation in Darwin's finches: Ghosts of finches future AI翻译
  作者：Podos, Jeffrey; Schroeder, Katie M.
  作者单位：University of Massachusetts System; University of Massachusetts Amherst; University of Massachusetts System; University of Massachusetts Amherst
  摘要：The theory of ecological speciation posits that adaptive divergence among incipient species raises incidental barriers to reproduction, thus catalyzing the emergence of new species. In this study, we conducted an experimental test of this theory in Gal & aacute;pagos finches, a clade in which beaks and mating songs are mechanistically linked. We forecasted the acoustic structure of songs for a set of possible evolutionary futures (successive droughts spurring increasingly large beaks) and, in ...
• Seed disperser declines threaten Europe's plants AI翻译
  作者：Stokstad, Erik
• El Nino fingered as likely culprit in record 2023 temperatures AI翻译
  作者：Voosen, Paul
• Protect white rhinos by legalizing horn trade AI翻译
  作者：Wikelski, Martin
  作者单位：Max Planck Society; University of Konstanz