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作者：Hampton, Stephanie E.; Powers, Stephen M.; Dugan, Hilary A.; Knoll, Lesley B.; McMeans, Bailey C.; Meyer, Michael F.; O'Reilly, Catherine M.; Ozersky, Ted; Sharma, Sapna; Barrett, David C.; Chandra, Sudeep; Jansen, Joachim; McClure, Ryan P.; Rautio, Milla; Weyhenmeyer, Gesa A.; Yang, Xiao
作者单位：Carnegie Institution for Science; Baylor University; University of Wisconsin System; University of Wisconsin Madison; University System of Ohio; Miami University; University of Toronto; University Toronto Mississauga; United States Department of the Interior; United States Geological Survey; Illinois State University; University of Minnesota System; University of Minnesota Duluth; Large Lakes Observatory; University of Minnesota Twin Cities; University of Minnesota Hospital; York University - Canada; University of Calgary; Nevada System of Higher Education (NSHE); University of Nevada Reno; Uppsala University; University of Quebec; University of Quebec Chicoutimi; University of Quebec; University of Quebec Chicoutimi; Southern Methodist University
摘要：Climate change is reducing winter ice cover on lakes; yet, the full societal and environmental consequences of this ice loss are poorly understood. The socioeconomic implications of declining ice include diminished access to ice-based cultural activities, safety concerns in traversing ice, changes in fisheries, increases in shoreline erosion, and declines in water storage. Longer ice-free seasons allow more time and capacity for water to warm, threatening water quality and biodiversity. Food w...
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作者：Mendes, Sara Beatriz; Olesen, Jens Mogens; Memmott, Jane; Costa, Jose Miguel; Timoteo, Sergio; Dengucho, Ana Laura; Craveiro, Leonardo; Heleno, Ruben
作者单位：Universidade de Coimbra; Aarhus University; University of Bristol
摘要：Seed dispersal is crucial for ecosystem persistence, especially in fragmented landscapes, such as those common in Europe. Ongoing defaunation might compromise effective seed dispersal, but the conservation status of pairwise interactions remains unknown. With a literature review, we reconstructed the first European-wide seed dispersal network and evaluated the conservation status of interactions by assessing each interacting partner's IUCN (International Union for Conservation of Nature) conse...
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作者：Raut, Ravindra Krushnaji; Matsutani, Satoshi; Shi, Fuxing; Kataoka, Shuta; Poje, Margareta; Mitschke, Benjamin; Maeda, Satoshi; Tsuji, Nobuya; List, Benjamin
作者单位：Hokkaido University; Hokkaido University; Max Planck Society; Hokkaido University; Hokkaido University; National Institute for Materials Science
摘要：The stereoselective activation of alkanes constitutes a long-standing and grand challenge for chemistry. Although metal-containing enzymes oxidize alkanes with remarkable ease and selectivity, chemical approaches have largely been limited to transition metal-based catalytic carbon-hydrogen functionalizations. Alkanes can be protonated to form pentacoordinated carbonium ions and fragmented into smaller hydrocarbons in the presence of strong Br & oslash;nsted acids. However, catalytic stereocont...
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作者：Tsui, Carlson; Kallies, Axel
作者单位：University of Melbourne; Peter Doherty Institute
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作者：Ng, Shawn; Howshall, Casey; Ho, Thanh Nhat; Mai, Binh Khanh; Zhou, Yuebiao; Qin, Can; Tee, Kai Ze; Liu, Peng; Romiti, Filippo; Hoveyda, Amir H.
作者单位：Boston College; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Universites de Strasbourg Etablissements Associes; Universite de Strasbourg; University of Texas System; University of Texas Dallas
摘要：Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of >400 natural products with a broad spectrum of bioactivity, ranging from antidepressant and antimicrobial to anti-obesity and anticancer activity. Here, we present a scalable, regio-, site-, and enantioselective catalytic method for synthesis of cyclic beta-prenyl ketones, compounds that can be used for efficient syntheses of many PPAPs in high enantiomeric purity. The transformation is prenyl conjugate addition to cyclic bet...
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作者：Park, Sang Woo; Cobey, Sarah; Metcalf, C. Jessica E.; Levine, Jonathan M.; Grenfell, Bryan T.
作者单位：Princeton University; University of Chicago
摘要：Observations of pathogen community structure provide evidence for both the coexistence and replacement of related strains. Despite many studies of specific host-pathogen systems, a unifying framework for predicting the outcomes of interactions among pathogens has remained elusive. We address this gap by developing a pathogen invasion theory (PIT) based on modern ecological coexistence theory and testing the resulting framework against empirical systems. Across major human pathogens, PIT predic...
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作者：Cho, Adrian
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作者：Sahl, Steffen J.; Matthias, Jessica; Inamdar, Kaushik; Weber, Michael; Khan, Taukeer A.; Brueser, Christian; Jakobs, Stefan; Becker, Stefan; Griesinger, Christian; Broichhagen, Johannes; Hell, Stefan W.
作者单位：Max Planck Society; University of Gottingen; UNIVERSITY GOTTINGEN HOSPITAL; University of Gottingen; Max Planck Society
摘要：Optical investigations of nanometer distances between proteins, their subunits, or other biomolecules have been the exclusive prerogative of F & ouml;rster resonance energy transfer (FRET) microscopy for decades. In this work, we show that MINFLUX fluorescence nanoscopy measures intramolecular distances down to 1 nanometer-and in planar projections down to 1 angstrom-directly, linearly, and with angstrom precision. Our method was validated by quantifying well-characterized 1- to 10-nanometer d...
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作者：Nuijten, R. J. M.; Nguyen, T.; Eikelboom, J. A. J.; Drori, O.
作者单位：Wageningen University & Research
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作者：Offord, Catherine
