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作者：Noack, Frederik; Engist, Dennis; Gantois, Josephine; Gaur, Vasundhara; Hyjazie, Batoule F.; Larsen, Ashley; M'Gonigle, Leithen K.; Missirian, Anouch; Qaim, Matin; Sargent, Risa D.; Souza-Rodrigues, Eduardo; Kremen, Claire
作者单位：University of British Columbia; University of British Columbia; New York University; University of British Columbia; University of California System; University of California Santa Barbara; Simon Fraser University; INRAE; Universite de Toulouse; Universite Toulouse 1 Capitole; Toulouse School of Economics; University of Bonn; University of Bonn; University of Toronto; Centre for Economic Policy Research - UK
摘要：Genetically modified (GM) crops have been adopted by some of the world's leading agricultural nations, but the full extent of their environmental impact remains largely unknown. Although concerns regarding the direct environmental effects of GM crops have declined, GM crops have led to indirect changes in agricultural practices, including pesticide use, agricultural expansion, and cropping patterns, with profound environmental implications. Recent studies paint a nuanced picture of these envir...
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作者：Brainard, Jeffrey
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作者：Irrgeher, Johanna
作者单位：University of Leoben
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作者：Froese, Rainer; Pauly, Daniel
作者单位：Helmholtz Association; GEOMAR Helmholtz Center for Ocean Research Kiel; University of British Columbia
摘要：Current stock assessment models overestimate productivity and recovery trajectory
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作者：Wernert, Florian; Moparthi, Satish Babu; Pelletier, Florence; Laine, Jeanne; Simons, Eline; Moulay, Gilles; Rueda, Fanny; Jullien, Nicolas; Benkhelifa-Ziyyat, Sofia; Papandreou, Marie-Jeanne; Leterrier, Christophe; Vassilopoulos, Stephane
作者单位：Aix-Marseille Universite; Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); Sorbonne Universite; Sorbonne Universite
摘要：Clathrin-mediated endocytosis has characteristic features in neuronal dendrites and presynapses, but how membrane proteins are internalized along the axon shaft remains unclear. We focused on clathrin-coated structures and endocytosis along the axon initial segment (AIS) and their relationship to the periodic actin-spectrin scaffold that lines the axonal plasma membrane. A combination of super-resolution microscopy and platinum-replica electron microscopy on cultured neurons revealed that AIS ...
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作者：Brainard, Jeffrey
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作者：Yang, Zhenlin; Mameri, Amel; Cattoglio, Claudia; Lachance, Catherine; Florez Ariza, Alfredo Jose; Luo, Jie; Humbert, Jonathan; Sudarshan, Deepthi; Banerjea, Arul; Galloy, Maxime; Fradet-Turcotte, Amelie; Lambert, Jean-Philippe; Ranish, Jeff A.; Cote, Jacques; Nogales, Eva
作者单位：University of California System; University of California Berkeley; University of California System; University of California Berkeley; Howard Hughes Medical Institute; Laval University; University of California System; University of California Berkeley; University of California System; University of California Berkeley; Institute for Systems Biology (ISB); Laval University; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory
摘要：The human nucleosome acetyltransferase of histone H4 (NuA4)/Tat-interactive protein, 60 kilodalton (TIP60) coactivator complex, a fusion of the yeast switch/sucrose nonfermentable related 1 (SWR1) and NuA4 complexes, both incorporates the histone variant H2A.Z into nucleosomes and acetylates histones H4, H2A, and H2A.Z to regulate gene expression and maintain genome stability. Our cryo-electron microscopy studies show that, within the NuA4/TIP60 complex, the E1A binding protein P400 (EP400) su...
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作者：Brainard, Jeffrey
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作者：Guan, Zhibin
作者单位：University of California System; University of California Irvine
摘要：A naturally occurring fatty acid yields a set of adhesives with different properties
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作者：Wadman, Meredith
摘要：Interdisciplinary teams struggle to find a home in siloed federal grant-funding system
