2024

最新文章

• Bioresorbable shape-adaptive structures for ultrasonic monitoring of deep-tissue homeostasis AI翻译
  作者：Liu, Jiaqi; Liu, Naijia; Xu, Yameng; Wu, Mingzheng; Zhang, Haohui; Wang, Yue; Yan, Ying; Hill, Angela; Song, Ruihao; Xu, Zijie; Park, Minsu; Wu, Yunyun; Ciatti, Joanna L.; Gu, Jianyu; Luan, Haiwen; Zhang, Yamin; Yang, Tianyu; Ahn, Hak-Young; Li, Shupeng; Ray, Wilson Z.; Franz, Colin K.; Macewan, Matthew R.; Huang, Yonggang; Hammill, Chet W.; Wang, Heling; Rogers, John A.
  作者单位：Northwestern University; Washington University (WUSTL); Washington University (WUSTL); Northwestern University; Northwestern University; Washington University (WUSTL); Northwestern University; Northwestern University; Dankook University; Northwestern University; Shirley Ryan AbilityLab; Northwestern University; Feinberg School of Medicine; Northwestern University; Feinberg School of Medicine; Tsinghua University; Northwestern University; Feinberg School of Medicine
  摘要：Monitoring homeostasis is an essential aspect of obtaining pathophysiological insights for treating patients. Accurate, timely assessments of homeostatic dysregulation in deep tissues typically require expensive imaging techniques or invasive biopsies. We introduce a bioresorbable shape-adaptive materials structure that enables real-time monitoring of deep-tissue homeostasis using conventional ultrasound instruments. Collections of small bioresorbable metal disks distributed within thin, pH-re...
• Writing my ticket AI翻译
  作者：Rodriguez, Violeta J.
  作者单位：University of Illinois System; University of Illinois Urbana-Champaign
• Harvard researchers face hunger AI翻译
  作者：Brainard, Jeffrey
• SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity AI翻译
  作者：Araki, Yoichi; Rajkovich, Kacey E.; Gerber, Elizabeth E.; Gamache, Timothy R.; Johnson, Richard C.; Tran, Thanh Hai N.; Liu, Bian; Zhu, Qianwen; Hong, Ingie; Kirkwood, Alfredo; Huganir, Richard
  作者单位：Johns Hopkins University
  摘要：INTRODUCTION Experience-dependent changes in the strength of synaptic connections in the brain are essential for neuronal development and for brain processes such as learning and memory. Long-term potentiation (LTP) of synapses is a key form of synaptic plasticity that is widely recognized as a cellular model for the study of memory. Many forms of synaptic plasticity, including LTP, are mediated by long-lasting changes in the level of AMPA receptors (AMPARs), the major neurotransmitter recepto...
• Peru's zoning amendment endangers forests AI翻译
  作者：Martel, Carlos; Mendieta-Leiva, Glenda; Alvarez-Loayza, Patricia C.; Cano, Asuncion; Cosio, Eric G.; Decock, Cony; Farfan-Rios, William; Feeley, Kenneth; Coronado, Euridice Honorio; Huamantupa, Isau; Ibanez, Alfredo J.; de Diller, Juliane Koepcke; Leon, Blanca; Linares-Palomino, Reynaldo; Pena, Jose L. Marcelo; Millan, Betty; Moat, Justin F.; Pennington, R. Toby; Pitman, Nigel; Salinas, Norma; Rojas-VeraPinto, Roxana; Stevenson, Philip C.; Tovar, Carolina; Whaley, Oliver Q.; Young, Kenneth R.
  作者单位：Royal Botanic Gardens, Kew; Pontificia Universidad Catolica del Peru; Philipps University Marburg; Duke University; Universidad Nacional Mayor de San Marcos; Universite Catholique Louvain; Wake Forest University; University of Miami; University of St Andrews; Universidad Nacional Amazonica De Madre De Dios; University of Texas System; University of Texas Austin; Smithsonian Institution; Smithsonian National Zoological Park & Conservation Biology Institute; Universidad Nacional de Jaen; University of Exeter; Field Museum of Natural History (Chicago); University of Reading; University of Greenwich
• The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants AI翻译
  作者：Materna, Marie; Delmonte, Ottavia M.; Bosticardo, Marita; Momenilandi, Mana; Conrey, Peyton E.; Charmeteau-De Muylder, Benedicte; Bravetti, Clotilde; Bellworthy, Rebecca; Cederholm, Axel; Staels, Frederik; Ganoza, Christian A.; Darko, Samuel; Sayed, Samir; Le Floc'h, Corentin; Ogishi, Masato; Rinchai, Darawan; Guenoun, Andrea; Bolze, Alexandre; Khan, Taushif; Gervais, Adrian; Krueger, Renate; Voeller, Mirjam; Palterer, Boaz; Sadeghi-Shabestari, Mahnaz; de Septenville, Anne Langlois; Schramm, Chaim A.; Shah, Sanjana; Tello-Cajiao, John J.; Pala, Francesca; Amini, Kayla; Campos, Jose S.; Lima, Noemia Santana; Eriksson, Daniel; Levy, Romain; Seeleuthner, Yoann; Jyonouchi, Soma; Ata, Manar; Al Ali, Fatima; Deswarte, Caroline; Pereira, Anais; Megret, Jerome; Le Voyer, Tom; Bastard, Paul; Berteloot, Laureline; Dussiot, Michael; Vladikine, Natasha; Cardenas, Paula P.; Jouanguy, Emmanuelle; Alqahtani, Mashael; Hasan, Amal; Thanaraj, Thangavel Alphonse; Rosain, Jeremie; Al Qureshah, Fahd; Sabato, Vito; Alyanakian, Marie Alexandra; Leruez-Ville, Marianne; Rozenberg, Flore; Haddad, Elie; Regueiro, Jose R.; Toribio, Maria L.; Kelsen, Judith R.; Salehi, Mansoor; Nasiri, Shahram; Torabizadeh, Mehdi; Rokni-Zadeh, Hassan; Changi-Ashtiani, Majid; Vatandoost, Nasimeh; Moravej, Hossein; Akrami, Seyed Mohammad; Mazloomrezaei, Mohsen; Cobat, Aurelie; Meyts, Isabelle; Toyofuku, Etsushi; Nishimura, Madoka; Moriya, Kunihiko; Mizukami, Tomoyuki; Imai, Kohsuke; Abel, Laurent; Malissen, Bernard; Al-Mulla, Fahd; Alkuraya, Fowzan Sami; Parvaneh, Nima; von Bernuth, Horst; Beetz, Christian; Davi, Frederic; Douek, Daniel C.; Cheynier, Remi; Langlais, David; Landegren, Nils; Marr, Nico; Morio, Tomohiro; Shahrooei, Mohammad; Schrijvers, Rik; Henrickson, Sarah E.; Luche, Herve; Notarangelo, Luigi D.; Casanova, Jean-Laurent; Beziat, Vivien
  作者单位：Assistance Publique Hopitaux Paris (APHP); Universite Paris Cite; Hopital Universitaire Necker-Enfants Malades - APHP; Institut National de la Sante et de la Recherche Medicale (Inserm); Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Paris Cite; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Paris Cite; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Assistance Publique Hopitaux Paris (APHP); Hopital Universitaire Pitie-Salpetriere - APHP; Sorbonne Universite; Sorbonne Universite; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Paris Cite; Sorbonne Universite; McGill University; Uppsala University; KU Leuven; CENTOGENE AG; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); Rockefeller University; Sidra Medical & Research Center; Jackson Laboratory; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Free University of Berlin; Humboldt University of Berlin; Humboldt University of Berlin; Free University of Berlin; Charite Universitatsmedizin Berlin; Berlin Institute of Health; Tabriz University of Medical Science; University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; Uppsala University; Uppsala University; Uppsala University Hospital; Assistance Publique Hopitaux Paris (APHP); Universite Paris Cite; Hopital Universitaire Necker-Enfants Malades - APHP; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Institut National de la Sante et de la Recherche Medicale (Inserm); Assistance Publique Hopitaux Paris (APHP); Universite Paris Cite; Hopital Universitaire Necker-Enfants Malades - APHP; Universite Paris Cite; Institut National de la Sante et de la Recherche Medicale (Inserm); Complutense University of Madrid; King Faisal Specialist Hospital & Research Center; Dasman Diabetes Institute (DDI); Dasman Diabetes Institute (DDI); University of Antwerp; Assistance Publique Hopitaux Paris (APHP); Universite Paris Cite; Hopital Universitaire Necker-Enfants Malades - APHP; Assistance Publique Hopitaux Paris (APHP); Universite Paris Cite; Hopital Universitaire Necker-Enfants Malades - APHP; Assistance Publique Hopitaux Paris (APHP); Universite Paris Cite; Hopital Universitaire Cochin - APHP; Universite de Montreal; Centre Hospitalier Universitaire Sainte-Justine; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Centro de Biologia Molecular Severo Ochoa (CBM); Autonomous University of Madrid; University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; Isfahan University of Medical Sciences; Isfahan University of Medical Sciences; Ahvaz Jundishapur University of Medical Sciences (AJUMS); Ahvaz Jundishapur University of Medical Sciences (AJUMS); Institute for Research in Fundamental Sciences IPM; Isfahan University of Medical Sciences; Shiraz University of Medical Science; Tehran University of Medical Sciences; KU Leuven; University Hospital Leuven; KU Leuven; University Hospital Leuven; Institute of Science Tokyo; Tokyo Medical & Dental University (TMDU); National Defense Medical College - Japan; Aix-Marseille Universite; Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); Aix-Marseille Universite; Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); Alfaisal University; Tehran University of Medical Sciences; Humboldt University of Berlin; Free University of Berlin; Charite Universitatsmedizin Berlin; Berlin Institute of Health; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Karolinska Institutet; Qatar Foundation (QF); Hamad Bin Khalifa University-Qatar; KU Leuven; University of Pennsylvania; University of Pennsylvania; Assistance Publique Hopitaux Paris (APHP); Universite Paris Cite; Hopital Universitaire Necker-Enfants Malades - APHP; Howard Hughes Medical Institute; Rockefeller University; Saint Marianna University
  摘要：We describe humans with rare biallelic loss-of-function PTCRA variants impairing pre-alpha T cell receptor (pre-TCR alpha) expression. Low circulating naive alpha beta T cell counts at birth persisted over time, with normal memory alpha beta and high gamma delta T cell counts. Their TCR alpha repertoire was biased, which suggests that noncanonical thymic differentiation pathways can rescue alpha beta T cell development. Only a minority of these individuals were sick, with infection, lymphoprol...
• Stop arguing and cut emissions AI翻译
  作者：Morgan, M. Granger; Apt, Jay
  作者单位：Carnegie Mellon University; Carnegie Mellon University; Carnegie Mellon University; Carnegie Mellon University; Carnegie Mellon University
  摘要：The expert and policy communities have invested enormous effort in debating what greenhouse gas (GHG) emissions target to aim for, or which decarbonization policies and technologies should be mandated or banned. Because multiple trajectories can achieve similar targets and timelines, some scenario analysis is useful. However, with many players involved, it will be impossible to remain on anyone's optimal trajectory. As one of the world's largest contributors to the climate crisis, the US shoul...
• Nicaraguan government puts mining over justice AI翻译
  作者：Oliveira, Rafael F.; Ottoni, Felipe P.; Vieira, Lucas O.; Obando, Grettel N.; Saenz, Ronald; Campos, Diego S.
  作者单位：Universidade Federal do Maranhao; Universidade Federal do Maranhao; Universidad de Chile; UOC Universitat Oberta de Catalunya
• Early end for private Moon lander AI翻译
  作者：Brainard, Jeffrey
• Wanted: scientific bounty hunters AI翻译
  作者：Brainard, Jeffrey