作者:Stein, Lisa Y.; Lidstrom, Mary E.
作者单位:University of Alberta; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle
摘要:Strategies to mitigate emissions must consider methane and nitrous oxide together
作者:Rice, Aaron N.
作者单位:Cornell University; Cornell University
作者:Spoorthi, B. K.; Debnath, Koyendrila; Basuri, Pallab; Nagar, Ankit; Waghmare, Umesh V.; Pradeep, Thalappil
作者单位:Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Madras; Department of Science & Technology (India); Jawaharlal Nehru Center for Advanced Scientific Research (JNCASR); Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Madras
摘要:In this work, we show that particles of common minerals break down spontaneously to form nanoparticles in charged water microdroplets within milliseconds. We transformed micron-sized natural minerals like quartz and ruby into 5- to 10-nanometer particles when integrated into aqueous microdroplets generated via electrospray. We deposited the droplets on a substrate, which allowed nanoparticle characterization. We determined through simulations that quartz undergoes proton-induced slip, especial...
作者:Taylor, Mark A.; Kandyba, Eve; Halliwill, Kyle; Delrosario, Reyno; Khoroshkin, Matvei; Goodarzi, Hani; Quigley, David; Li, Yun Rose; Wu, Di; Bollam, Saumya R.; Mirzoeva, Olga K.; Akhurst, Rosemary J.; Balmain, Allan
作者单位:University of California System; University of California San Francisco; UCSF Medical Center; UCSF Helen Diller Family Comprehensive Cancer Center; Medical University of Bialystok; AbbVie; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; City of Hope; City of Hope; University of California System; University of California San Francisco; University of California System; University of California San Francisco
摘要:Stem cells play a critical role in cancer development by contributing to cell heterogeneity, lineage plasticity, and drug resistance. We created gene expression networks from hundreds of mouse tissue samples (both normal and tumor) and integrated these with lineage tracing and single-cell RNA-seq, to identify convergence of cell states in premalignant tumor cells expressing markers of lineage plasticity and drug resistance. Two of these cell states representing multilineage plasticity or proli...