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作者:Radolinski, Jesse; Vremec, Matevz; Wachter, Herbert; Birk, Steffen; Brueggemann, Nicolas; Herndl, Markus; Kahmen, Ansgar; Nelson, Daniel B.; Kuebert, Angelika; Schaumberger, Andreas; Stumpp, Christine; Tissink, Maud; Werner, Christiane; Bahn, Michael
作者单位:University of Innsbruck; University System of Maryland; University of Maryland College Park; University of Graz; Helmholtz Association; Julich Research Centre; University of Basel; University of Helsinki; BOKU University; University of Freiburg
摘要:Soil water sustains terrestrial life, yet its fate is uncertain under a changing climate. We conducted a deuterium labeling experiment to determine whether elevated atmospheric carbon dioxide (CO2), warming, and drought impact soil water storage and transport in a temperate grassland. Elevated CO2 created a wetter rootzone compared with ambient conditions, whereas warming decreased soil moisture. Soil water remained well mixed in all global change treatments except for summer drought combined ...
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作者:Wild, Kristoffer H.; Huey, Raymond B.; Pianka, Eric R.; Clusella-Trullas, Susana; Gilbert, Anthony L.; Miles, Donald B.; Kearney, Michael R.
作者单位:University of Melbourne; University of Washington; University of Washington Seattle; University of Texas System; University of Texas Austin; Stellenbosch University; Stellenbosch University; Auburn University System; Auburn University; University System of Ohio; Ohio University
摘要:Climate warming can induce a cost-of-living squeeze in ectotherms by increasing energetic expenditures while reducing foraging gains. We used biophysical models (validated by 2685 field observations) to test this hypothesis for 10 ecologically diverse lizards in African and Australian deserts. Historical warming (1950-2020) has been more intense in Africa than in Australia, translating to an energetic squeeze for African diurnal species. Although no net impact on Australian diurnal species was...
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作者:Maillard, Oswaldo; Vides-Almonacid, Roberto
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作者:Ongaro, Luisina; Zhou, Xiang; Wang, Ying; Schultz, Hailey; Zhou, Ziyue; Buddle, Evan R. S.; Brule, Emilie; Lin, Yeu-Farn; Schang, Gauthier; Hagg, Adam; Castonguay, Roselyne; Liu, Yewei; Su, Gloria H.; Seidah, Nabil G.; Ray, Kevin C.; Karp, Seth J.; Boehm, Ulrich; Ruf-Zamojski, Frederique; Sealfon, Stuart C.; Walton, Kelly L.; Lee, Se-Jin; Bernard, Daniel J.
作者单位:McGill University; McGill University; University of Queensland; Jackson Laboratory; Columbia University; Institut de Recherche Clinique de Montreal (IRCM); Universite de Montreal; Vanderbilt University; Saarland University; Cedars Sinai Medical Center; Icahn School of Medicine at Mount Sinai; University of Connecticut
摘要:Myostatin is a paracrine myokine that regulates muscle mass in a variety of species, including humans. In this work, we report a functional role for myostatin as an endocrine hormone that directly promotes pituitary follicle-stimulating hormone (FSH) synthesis and thereby ovarian function in mice. Previously, this FSH-stimulating role was attributed to other members of the transforming growth factor-beta family, the activins. Our results both challenge activin's eponymous role in FSH synthesis...
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作者:Tawfick, Sameh; Arretche, Ignacio
作者单位:University of Illinois System; University of Illinois Urbana-Champaign
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作者:Brainard, Jeffrey
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作者:Brainard, Jeffrey
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作者:Luedecke, Tina; Leichliter, Jennifer N.; Stratford, Dominic; Sigman, Daniel M.; Vonhof, Hubert; Haug, Gerald H.; Bamford, Marion K.; Martinez-Garcia, Alfredo
作者单位:Max Planck Society; Max Planck Society; University of Witwatersrand; University of Witwatersrand; State University of New York (SUNY) System; Stony Brook University; Princeton University; Swiss Federal Institutes of Technology Domain; ETH Zurich
摘要:Incorporation of animal-based foods into early hominin diets has been hypothesized to be a major catalyst of many important evolutionary events, including brain expansion. However, direct evidence of the onset and evolution of animal resource consumption in hominins remains elusive. The nitrogen-15 to nitrogen-14 ratio of collagen provides trophic information about individuals in modern and geologically recent ecosystems (<200,000 years ago), but diagenetic loss of this organic matter preclude...
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作者:Zhang, Zehao; Schaefer, Chloe; Jiang, Weirong; Lu, Ziyu; Lee, Jasper; Sziraki, Andras; Abdulraouf, Abdulraouf; Wick, Brittney; Haeussler, Maximilian; Li, Zhuoyan; Molla, Gesmira; Satija, Rahul; Zhou, Wei; Cao, Junyue
作者单位:Rockefeller University; Rockefeller University; University of California System; University of California Santa Cruz; New York University
摘要:To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling >20 million cells from 623 mouse tissues across different life stages, sexes, and genotypes. This comprehensive dataset reveals >3000 different cellular states and >200 aging-associated cell populations. Our panoramic analysis uncovered organ-, lineage-, and sex-specific shifts in cellular dynamics during life-span progression. Moreover, we identify both systematic and org...
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作者:Brainard, Jeffrey