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作者:Mccombe, Carl L.; Wegner, Alex; Wirtz, Louisa; Zamora, Chenie S.; Casanova, Florencia; Aditya, Shouvik; Greenwood, Julian R.; de Paula, Samuel; England, Eleanor; Shang, Sascha; Ericsson, Daniel J.; Oliveira-Garcia, Ely; Williams, Simon J.; Schaffrath, Ulrich
作者单位:Australian National University; RWTH Aachen University; Louisiana State University System; Louisiana State University; Australian Nuclear Science & Technology Organisation; Australian Synchrotron
摘要:Inorganic phosphate (Pi) is essential for life, and plant cells monitor Pi availability by sensing inositol pyrophosphate (PP-InsP) levels. In this work, we describe the hijacking of plant phosphate sensing by a conserved family of Nudix hydrolase effectors from pathogenic Magnaporthe and Colletotrichum fungi. Structural and enzymatic analyses of the Nudix effector family demonstrate that they selectively hydrolyze PP-InsP. Gene deletion experiments of Nudix effectors in Magnaporthe oryzae, Co...
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作者:Dura-Aleman, Carlos Javier; Lopez-Bao, Jose Vicente
作者单位:Consejo Superior de Investigaciones Cientificas (CSIC); CSIC-IESA - Instituto de Estudios Sociales Avanzados; Consejo Superior de Investigaciones Cientificas (CSIC)
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作者:Miao, Pei; Wang, Haijun; Wang, Wei; Wang, Zhengdong; Ke, Han; Cheng, Hangyuan; Ni, Jinjing; Liang, Jingnan; Yao, Yu-Feng; Wang, Jizong; Zhou, Jian-Min; Lei, Xiaoguang
作者单位:Chinese Academy of Sciences; Institute of Genetics & Developmental Biology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Yazhouwan National Laboratory; Peking University; Peking University; Peking University; Peking University; Chinese Academy of Sciences; Shanghai Jiao Tong University; Chinese Academy of Sciences; Institute of Microbiology, CAS
摘要:Numerous gram-negative bacterial pathogens employ the type III secretion system (T3SS), a multiprotein injectisome, to deliver virulence proteins into host cells and cause diseases. We uncover erucamide as a previously unknown phytoalexin of both dicots and monocots that blocks the T3SS function of multiple bacterial pathogens. Genetically impairing erucamide accumulation or exogenous application in Arabidopsis highlighted erucamide's role in antibacterial immunity. Erucamide binds Hypersensit...
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作者:Thorp, H. Holden
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作者:Zhang, Chao; Nielsen, Rasmus; Mirarab, Siavash
作者单位:University of Copenhagen; University of California System; University of California San Diego; University of California System; University of California Berkeley; University of California System; University of California San Diego
摘要:Genomes contain mosaics of discordant evolutionary histories, challenging the accurate inference of the tree of life. Although genome-wide data are routinely used for discordance-aware phylogenomic analyses, because of modeling and scalability limitations, the current practice leaves out large chunks of genomes. As more high-quality genomes become available, we urgently need discordance-aware methods to infer the tree directly from a multiple genome alignment. In this study, we introduce Coale...
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作者:Russo, Dominic R.; Gaiser, Alyssa N.; Price, Amy N.; Sergentu, Dumitru-Claudiu; Wacker, Jennifer N.; Katzer, Nicholas; Peterson, Appie A.; Branson, Jacob A.; Yu, Xiaojuan; Kelly, Sheridon N.; Ouellette, Erik T.; Arnold, John; Long, Jeffrey R.; Lukens Jr, Wayne W.; Teat, Simon J.; Abergel, Rebecca J.; Arnold, Polly L.; Autschbach, Jochen; Minasian, Stefan G.
作者单位:United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of California System; University of California Berkeley; Alexandru Ioan Cuza University; Alexandru Ioan Cuza University; State University of New York (SUNY) System; University at Buffalo, SUNY; University of California System; University of California Berkeley; University of California System; University of California Berkeley; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of California System; University of California Berkeley
摘要:Interest in actinide-carbon bonds has persisted since actinide organometallics were first investigated for applications in isotope separation during the Manhattan Project. Transplutonium organometallics are rarely isolated and structurally characterized, likely owing to limited isotope inventories, a scarcity of suitable laboratory infrastructure, and intrinsic difficulties with the anaerobic conditions required. Herein, we report the discovery of an organometallic berkelocene complex prepared...
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作者:Laurent, Sean M.
作者单位:Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park
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作者:Sayin, Sercan; Couzin-Fuchs, Einat; Petelski, Inga; Guenzel, Yannick; Salahshour, Mohammad; Lee, Chi-Yu; Graving, Jacob M.; Li, Liang; Deussen, Oliver; Sword, Gregory A.; Couzin, Iain D.
作者单位:University of Konstanz; Max Planck Society; University of Konstanz; Max Planck Society; University of Konstanz; Texas A&M University System; Texas A&M University College Station
摘要:Collective motion, which is ubiquitous in nature, has traditionally been explained by self-propelled particle models from theoretical physics. Here we show, through field, lab, and virtual reality experimentation, that classical models of collective behavior cannot account for how collective motion emerges in marching desert locusts, whose swarms affect the livelihood of millions. In contrast to assumptions made by these models, locusts do not explicitly align with neighbors. While individuals...
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作者:Ye, Jingyun; Dimitratos, Nikolaos; Rossi, Liane M.; Thonemann, Nils; Beale, Andrew M.; Wojcieszak, Robert
作者单位:Duquesne University; University of Bologna; Universidade de Sao Paulo; Leiden University - Excl LUMC; Leiden University; University of London; University College London; UK Research & Innovation (UKRI); Science & Technology Facilities Council (STFC); STFC Rutherford Appleton Laboratory; Centre National de la Recherche Scientifique (CNRS); Universite de Lorraine; Universite de Lille; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); Universite d'Artois; Centrale Lille
摘要:Catalytic carbon dioxide (CO2) hydrogenation is a potential route for producing sustainable fuels and chemicals, but existing catalysts need improvement. In particular, identifying active sites and understanding the interaction between components and the dynamic behavior of the participant species remain unclear. This fundamental knowledge is essential for the design of more efficient and stable catalysts. Because the nature of the active site (metal, oxide, carbide) is the main factor that de...
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作者:Wan, Siyu; Xia, Xiuyang; Gao, Yutong; Zhang, Heyang; Zhang, Zhebin; Wu, Fangyue; Wu, Xuesong; Yang, Dong; Li, Tongtao; Li, Jianfeng; Ni, Ran; Dong, Angang
作者单位:Fudan University; Fudan University; Nanyang Technological University; Fudan University
摘要:Shape-anisotropic nanocrystals and patchy particles have been explored to construct complex superstructures, but most studies have focused on convex shapes. We report that nonconvex, dumbbell-shaped nanocrystals (nanodumbbells) exhibit globally interlocking self-assembly behaviors governed by curvature-guided depletion interactions. By tailoring the local curvature of nanodumbbells, we can precisely and flexibly adjust particle bonding directionality, a level of control rarely achievable with ...