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作者：Lin, Jing-Ping; Brake, Alexis; Donadieu, Maxime; Lee, Amanda; Smith, Ginger; Hu, Kevin; Nair, Govind; Kawaguchi, Riki; Sati, Pascal; Geschwind, Daniel H.; Jacobson, Steven; Schafer, Dorothy P.; Reich, Daniel S.
作者单位：National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS); University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; Cedars Sinai Medical Center; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS); University of Massachusetts System; UMass Chan Medical School; University of Massachusetts Worcester
摘要：Inferring cellular and molecular dynamics of multiple sclerosis (MS) lesions from postmortem tissue collected decades after onset is challenging. Using magnetic resonance image (MRI)-guided spatiotemporal RNA profiling in marmoset experimental autoimmune encephalitis (EAE), we mapped lesion dynamics and modeled molecular perturbations relevant to MS. Five distinct lesion microenvironments emerged, involving neuroglial responses, tissue destruction and repair, and brain border regulation. Befor...
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作者：Ye, Ziwei; Difonzo, Christina; Hennessy, David A.; Zhao, Jinhua; Wu, Felicia; Conley, Shawn P.; Gassmann, Aaron J.; Hodgson, Erin W.; Jensen, Bryan; Knodel, Janet J.; Mcmanus, Bradley; Meinke, Lance J.; Michel, Andrew; Potter, Bruce; Seiter, Nicholas J.; Smith, Jocelyn L.; Spencer, Joseph L.; Tilmon, Kelley J.; Wright, Robert J.; Krupke, Christian H.
作者单位：Renmin University of China; Michigan State University; Iowa State University; Iowa State University; Cornell University; Michigan State University; Michigan State University; University of Wisconsin System; University of Wisconsin Madison; Iowa State University; University of Wisconsin System; University of Wisconsin Madison; North Dakota State University Fargo; South Dakota State University; University of Nebraska System; University of Nebraska Lincoln; University System of Ohio; Ohio State University; University of Minnesota System; University of Illinois System; University of Illinois Urbana-Champaign; University of Guelph; Illinois Natural History Survey; University of Illinois System; University of Illinois Urbana-Champaign; Purdue University System; Purdue University
摘要：Widespread use of genetically engineered maize targeting the corn rootworm complex (Diabrotica species) has raised concerns about insect resistance. Twelve years of university field trial and farm survey data from 10 US Corn Belt states indicate that maize hybrids expressing toxins derived from the bacterium Bacillus thuringiensis (Bt maize) exhibited declining protection from rootworm feeding with increased planting while pest pressures simultaneously decreased. The analysis revealed a tenden...
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作者：Lawrence, Andy
作者单位：University of Edinburgh
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作者：[Anonymous]
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作者：Barker, Stephen; Lisiecki, Lorraine E.; Knorr, Gregor; Nuber, Sophie; Tzedakis, Polychronis C.
作者单位：Cardiff University; University of California System; University of California Santa Barbara; Helmholtz Association; Alfred Wegener Institute, Helmholtz Centre for Polar & Marine Research; University of London; University College London; University of Washington; University of Washington Seattle
摘要：Identifying the specific roles of precession, obliquity, and eccentricity in glacial-interglacial transitions is hindered by imprecise age control. We circumvent this problem by focusing on the morphology of deglaciation and inception, which we show depends strongly on the relative phasing of precession versus obliquity. We demonstrate that although both parameters are important, precession has more influence on deglacial onset, whereas obliquity is more important for the attainment of peak in...
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作者：Chaudhary, V. Bala; Kim, Sora; Medina, Monica; Srivastava, Diane S.; Traylor-Knowles, Nikki; Brito-Millan, Marlene; Camargo-Cely, Alejandra; Chatterjee, Snehanjana; Chen, Nancy; Chen, Yolanda H.; Gotanda, Kiyoko M.; Halsey, Samniqueka J.; Jack, Chandra N.; Mcguire, Rosa M.; Miller, Cassandra M. L.; Moore, Alex C.; Noh, Suegene; Ong, Theresa W.; Peralta, Ariane L.; Puitiza, Amanda; Ramirez, Lucia N.; Romero-Olivares, Adriana L.; Pulido-Barriga, M. Fabiola; Sanchez, Karina A.; Sit, Christine Y.; Su, Chenyang; Vazquez-Cardona, Juleyska; Venkataraman, Yaamini R.; Werner, Chhaya M.; Khadempour, Lily
作者单位：Dartmouth College; University of California System; University of California Merced; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; University of British Columbia; University of British Columbia; University of Miami; Loyola University Chicago; Boston University; Texas Tech University System; Texas Tech University; University of Rochester; University of Vermont; Brock University; University of Missouri System; University of Missouri Columbia; Clark University; Stanford University; University of New Mexico; University of Minnesota System; University of Minnesota Twin Cities; University of British Columbia; Colby College; University of North Carolina; East Carolina University; Oregon State University; North Carolina State University; New Mexico State University; University of California System; University of California Irvine; University System Of New Hampshire; University of New Hampshire; University of Michigan System; University of Michigan; University of Lethbridge; Woods Hole Oceanographic Institution; Rutgers University System; Rutgers University Newark
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作者：Langin, Katie
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作者：Crozier, Peter A.; Leibovich, Matan; Haluai, Piyush; Tan, Mai; Thomas, Andrew M.; Vincent, Joshua; Mohan, Sreyas; Morales, Adria Marcos; Kulkarni, Shreyas A.; Matteson, David S.; Wang, Yifan; Fernandez-Granda, Carlos
作者单位：Arizona State University; Arizona State University-Tempe; New York University; University of Iowa; New York University; Cornell University
摘要：Materials functionalities may be associated with atomic-level structural dynamics occurring on the millisecond timescale. However, the capability of electron microscopy to image structures with high spatial resolution and millisecond temporal resolution is often limited by poor signal-to-noise ratios. With an unsupervised deep denoising framework, we observed metal nanoparticle surfaces (platinum nanoparticles on cerium oxide) in a gas environment with time resolutions down to 10 milliseconds ...
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作者：Reilly, Christopher S.; Auerbach, Daniel J.; Zhang, Liang; Guo, Hua; Beck, Rainer D.
作者单位：Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; University of New Mexico
摘要：Although the dynamics of collisions between a molecule and a solid surface are ultimately quantum mechanical, decohering effects owing to the large number of interacting degrees of freedom typically obscure the wavelike nature of these events. However, a partial decoupling of internal molecular motion from external degrees of freedom can reveal striking interference effects despite significant momentum exchange between the molecule and the bath of surface vibrations. We report state-prepared a...
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作者：Korgel, Brian A.
作者单位：University of Texas System; University of Texas Austin
