6729期

最新文章

• Organic ionic plastic crystals having colossal barocaloric effects for sustainable refrigeration AI翻译
  作者：Piper, Samantha L.; Melag, Leena; Kar, Mega; Sourjah, Azra; Xiao, Xiong; May, Eric F.; Aguey-Zinsou, Kondo-Francois; MacFarlane, Douglas R.; Pringle, Jennifer M.
  作者单位：Deakin University; University of Western Australia; University of Sydney; Monash University; Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Mineral Resources
  摘要：Barocaloric (BC) materials offer the potential for highly energy-efficient refrigeration by generating heat absorption through the effect of pressure on a solid-solid phase transition. However, very few of the known materials have the required phase transition in the temperature regions necessary for domestic refrigeration or air conditioning. We introduce organic ionic plastic crystals (OIPCs) as a new family of BC materials. OIPCs display subambient transition temperatures, so-called colossa...
• Charting the changing sky AI翻译
  作者：Brainard, Jeffrey; Servick, Kelly
• Peak emissions at last? AI翻译
  作者：Brainard, Jeffrey; Servick, Kelly
• Can war-torn Syria rebuild its scientific community? AI翻译
  作者：Stone, Richard
• Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein AI翻译
  作者：Dacon, Cherrelle; Moskovitz, Re'em; Swearingen, Kristian; Pereira, Lais Da Silva; Flores-Garcia, Yevel; Aleshnick, Maya; Kanatani, Sachie; Flynn, Barbara; Molina-Cruz, Alvaro; Wollenberg, Kurt; Traver, Maria; Kirtley, Payton; Purser, Lauren; Dillon, Marlon; Bonilla, Brian; Franco, Adriano; Petros, Samantha; Kritzberg, Jake; Tucker, Courtney; Paez, Gonzalo Gonzalez; Gupta, Priya; Shears, Melanie J.; Pazzi, Joseph; Edgar, Joshua M.; Teng, Andy A.; Belmonte, Arnel; Oda, Kyosuke; Doumbo, Safiatou; Krymskaya, Ludmila; Skinner, Jeff; Li, Shanping; Ghosal, Suman; Kayentao, Kassoum; Ongoiba, Aissata; Vaughan, Ashley; Campo, Joseph J.; Traore, Boubacar; Barillas-Mury, Carolina; Wijayalath, Wathsala; Idris, Azza; Crompton, Peter D.; Sinnis, Photini; Wilder, Brandon K.; Zavala, Fidel; Seder, Robert A.; Wilson, Ian A.; Tan, Joshua
  作者单位：National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); Scripps Research Institute; Institute for Systems Biology (ISB); National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Oregon Health & Science University; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); Catholic University of America; Seattle Children's Hospital; University of Washington; University of Washington Seattle; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc; University of Science & Technology of Bamako; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); Harvard University; Massachusetts Institute of Technology (MIT); Ragon Institute; Harvard University Medical Affiliates; Massachusetts General Hospital; Scripps Research Institute
  摘要：The most advanced monoclonal antibodies (mAbs) and vaccines against malaria target the central repeat region or closely related sequences within the Plasmodium falciparum circumsporozoite protein (PfCSP). Here, using an antigen-agnostic strategy to investigate human antibody responses to whole sporozoites, we identified a class of mAbs that target a cryptic PfCSP epitope that is only exposed after cleavage and subsequent pyroglutamylation (pGlu) of the newly formed N terminus. This pGlu-CSP ep...
• Direct photoreception by pituitary endocrine cells regulates hormone release and pigmentation AI翻译
  作者：Fukuda, Ayaka; Sato, Keita; Fujimori, Chika; Yamashita, Takahiro; Takeuchi, Atsuko; Ohuchi, Hideyo; Umatani, Chie; Kanda, Shinji
  作者单位：University of Tokyo; Okayama University; Kyoto University; Kobe Pharmaceutical University; University of Tokyo; National Institutes of Natural Sciences (NINS) - Japan; National Institute for Basic Biology (NIBB); Hokkaido University; Tokyo University of Agriculture & Technology
  摘要：The recent discovery of nonvisual photoreceptors in various organs has raised expectations for uncovering their roles and underlying mechanisms. In this work, we identified a previously unrecognized hormone-releasing mechanism in the pituitary of the Japanese rice fish (medaka) induced by light. Ca2+ imaging analysis revealed that melanotrophs, a type of pituitary endocrine cell that secretes melanocyte-stimulating hormone, robustly increase the concentration of intracellular Ca2+ during short...
• Ancient structural variants control sex-specific flowering time morphs in walnuts and hickories AI翻译
  作者：Groh, Jeffrey S.; Vik, Diane C.; Davis, Matthew; Monroe, J. Grey; Stevens, Kristian A.; Brown, Patrick J.; Langley, Charles H.; Coop, Graham
  作者单位：University of California System; University of California Davis; University of California System; University of California Davis; University of California System; University of California Davis; University of California System; University of California Davis
  摘要：Balanced mating type polymorphisms offer a distinct window into the forces shaping sexual reproduction strategies. Multiple hermaphroditic genera in Juglandaceae, including walnuts (Juglans) and hickories (Carya), show a 1:1 genetic dimorphism for male versus female flowering order (heterodichogamy). We map two distinct Mendelian inheritance mechanisms to ancient (>37 million years old) genus-wide structural DNA polymorphisms. The dominant haplotype for female-first flowering in Juglans contai...
• Loss of Earth's old, wise, and large animals AI翻译
  作者：Kopf, R. Keller; Banks, Sam; Brent, Lauren J. N.; Humphries, Paul; Jolly, Chris J.; Lee, Phyllis C.; Luiz, Osmar J.; Nimmo, Dale; Winemiller, Kirk O.
  作者单位：Charles Darwin University; University of Exeter; Charles Sturt University; Charles Sturt University; Macquarie University; University of Stirling; Texas A&M University System; Texas A&M University College Station
  摘要：Earth's old animals are in decline. Despite this, emerging research is revealing the vital contributions of older individuals to cultural transmission, population dynamics, and ecosystem processes and services. Often the largest and most experienced, old individuals are most valued by humans and make important contributions to reproduction, information acquisition and cultural transmission, trophic dynamics, and resistance and resilience to natural and anthropogenic disturbance. These observat...
• Care urged for animal remains tied to Indigenous peoples AI翻译
  作者：Heidt, Amanda
• Beyond misalignment of science in the news and in schools AI翻译
  作者：Erduran, Sibel
  作者单位：University of Oxford