6760期

最新文章

• Senate panel rejects Trump's plan to slash NIH's budget AI翻译
  作者：Kaiser, Jocelyn
• In Other Journals AI翻译
  作者：Simonti, Corinne; Smith, Jesse
• Improving Alzheimer's disease immunotherapy AI翻译
  作者：Xing, Mengen; Song, Weihong
  作者单位：Wenzhou Medical University; Oujiang Laboratory; Wenzhou Medical University; Wenzhou Medical University
• Quantum technology governance: A standards-first approach AI翻译
  作者：Aboy, Mateo; Gasser, Urs; Cohen, I. Glenn; Kop, Mauritz
  作者单位：University of Cambridge; University of Cambridge; Technical University of Munich; Harvard University; Stanford University
• The membrane skeleton is constitutively remodeled in neurons by calcium signaling AI翻译
  作者：Heller, Evan; Kurup, Naina; Zhuang, Xiaowei
  作者单位：Harvard University; Howard Hughes Medical Institute; Harvard University; Harvard University
  摘要：The membrane skeleton in neurons adopts a periodic lattice structure in which actin filaments, capped by adducin and tropomodulin, form ring-shaped structures connected by spectrin tetramers along neurites. This membrane-associated periodic skeleton (MPS) is important for many neuronal functions. Using live-cell super-resolution imaging, we found that the MPS is surprisingly dynamic, undergoing local disassembly and reformation constitutively in axons. MPS remodeling is driven by calcium signa...
• Convergence and divergence of individual immune responses over the life course AI翻译
  作者：Metcalf, C. Jessica E.; Graham, Andrea L.; Yates, Andrew J.; Cummings, Derek A. T.
  作者单位：Princeton University; Princeton University; The Santa Fe Institute; Columbia University; Cornell University; Weill Cornell Medicine; NewYork-Presbyterian Hospital; Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Johns Hopkins University
  摘要：Three ingredients create the strikingly variable immune trajectories observed across human populations: (i) genetic variation, (ii) individual-scale generation of additional genetic diversity solely in lymphocytes, and (iii) collision of these processes with a changing environment through life, triggering plastic responses that can have lasting effects. We explore what generates or reduces immune variation, integrating recent empirical advances with potential overarching evolutionary principle...
• The multifunctional immune system AI翻译
  作者：Ross, Sarah; Ash, Caroline
• Moire eyes detect the dim AI翻译
  作者：Bandurin, Denis
  作者单位：National University of Singapore
• How a diagnosis altered my path AI翻译
  作者：De Vuyst, Matteo
  作者单位：Ghent University
• Losing protection AI翻译
  作者：Enserink, Martin