-
作者：Thorp, H. Holden
-
作者：Gao, Yueze; Gupta, Prakhar; Roncevic, Igor; Mycroft, Coral; Gates, Paul J.; Parker, Anthony W.; Anderson, Harry L.
作者单位：University of Oxford; University of Manchester; University of Bristol; UK Research & Innovation (UKRI); Science & Technology Facilities Council (STFC); STFC Rutherford Appleton Laboratory
摘要：Cyclo[N]carbons, molecular rings consisting solely of N carbon atoms, have previously been studied in the gas phase and on surfaces at cryogenic temperatures, but they are generally considered too reactive to be studied under ambient laboratory conditions. In this study, we report the synthesis of a cyclo[48]carbon catenane, in which the C48 ring is protected by being threaded through three other macrocycles. This cyclo[48]carbon [4]catenane is stable enough for spectroscopic characterization ...
-
作者：Glaberman, Scott; Wei, Cynthia
作者单位：University of Birmingham; Georgetown University
-
作者：Maldacena, j.
-
作者：Wang, Jinxin; Yin, Yunpeng; Zhang, Quan; Zhang, Wei-Dong; Li, Jian
作者单位：Shanghai Jiao Tong University; Shanghai Jiao Tong University; Naval Medical University; Chinese Academy of Medical Sciences - Peking Union Medical College; Institute of Medicinal Plant Development - CAMS; Peking Union Medical College
摘要：Efficient asymmetric epoxidation reactions have been developed for both the head end and tail end double bonds of farnesol, greatly facilitating the synthesis of terpenoid natural products. However, the lack of methods for direct asymmetric epoxidation of the relatively inert internal alkene of farnesol has posed major challenges in the synthesis of many terpenoids. In this study, we describe the engineering of an epoxidase capable of selectively epoxidizing the internal alkene of farnesol wit...
-
作者：Medeiros, Tania Catarina; Ovciarikova, Jana; Li, Xianhe; Krueger, Patrick; Bartsch, Tim; Reato, Silvia; Crow, John C.; Tellez Sutterlin, Michelle; Martins Garcia, Bruna; Rais, Irina; Allmeroth, Kira; Hartman, Matias D.; Denzel, Martin S.; Purrio, Martin; Mesaros, Andrea; Leung, Kit-Yi; Greene, Nicholas D. E.; Sheiner, Lilach; Giavalisco, Patrick; Pernas, Lena
作者单位：Max Planck Society; University of Glasgow; University of California System; University of California Los Angeles; Howard Hughes Medical Institute; University of California System; University of California Los Angeles; Max Planck Society; Max Planck Society; University of London; University College London; Max Planck Society
摘要：As major consumers of cellular metabolites, mitochondria are poised to compete with invading microbes for the nutrients that they need to grow. Whether cells exploit mitochondrial metabolism to protect from infection is unclear. In this work, we found that the activating transcription factor 4 (ATF4) activates a mitochondrial defense based on the essential B vitamin folate. During infection of cultured mammalian cells with the intracellular pathogen Toxoplasma gondii, ATF4 increased mitochondr...
-
作者：Reardon, Sara
-
作者：Thoren, Markus Hiltunen; Olsson, Boel; Vonk, Peter Jan; Siljestam, Mattias; Reimegard, Johan; Ryberg, Martin; Johannesson, Hanna
作者单位：Stockholm University; Royal Swedish Academy of Sciences; Uppsala University
摘要：In sexual organisms, inheritance of new mutations is highly dependent on the timing of germline definition. Here, we used the fairy ring-forming fungus Marasmius oreades to challenge the general assumption of a late germline separation in the Fungi. We collected mushrooms from different parts of rings over a 7-year period and identified new mutations in different tissues by whole-genome sequencing. We found evidence that fertile and sterile tissues had accumulated different mutations, suggesti...
-
作者：Guo, Dongsheng; Liu, Zilin; Raaijmakers, Jos M.; Xu, Yachun; Yang, Jinghui; Erb, Matthias; Zhang, Jiabao; Zhu, Yong-Guan; Xu, Jianming; Hu, Lingfei
作者单位：Zhejiang University; Zhejiang University; Royal Netherlands Academy of Arts & Sciences; Netherlands Institute of Ecology (NIOO-KNAW); Leiden University; Leiden University - Excl LUMC; University of Bern; Chinese Academy of Sciences; Nanjing Institute of Soil Science, CAS; Chinese Academy of Sciences; Research Center for Eco-Environmental Sciences (RCEES), CAS
摘要：High planting density boosts crop yields but also heightens pest and pathogen risks. How plants adapt their defenses under these conditions remains unclear. In this study, we reveal that maize enhances its defense in high-density conditions through a plant-soil feedback mechanism triggered by the leaf volatile linalool. Linalool activates jasmonate signaling in neighboring plants and promotes root exudation of benzoxazinoids, especially 2-(2-hydroxy-4,7-dimethoxy-1,4-benzoxazin-3-one)-beta-d-g...
-
作者：Guo, Yanliang; Dhar, Sudipta; Yang, Ang; Chen, Zekai; Yao, Hepeng; Horvath, Milena; Ying, Lei; Landini, Manuele; Naegerl, Hanns-Christoph
作者单位：University of Innsbruck; University of Innsbruck; Zhejiang University; Zhejiang University; University of Geneva
摘要：The quantum kicked rotor is a paradigmatic model system in quantum physics. As a driven quantum system, it features dynamical localization, specifically Anderson localization in momentum space. However, the interacting many-body kicked rotor is believed to break localization. Here, we present evidence for many-body dynamical localization for the Lieb-Liniger version of the many-body quantum kicked rotor. After some initial evolution, the momentum distribution of interacting quantum-degenerate ...
