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作者：Murphy, Lauren; Inchauspe, Jeanne; Valenzano, Giampiero; Holland, Pamela; Sousos, Nikolaos; Belnoue-Davis, Hayley L.; Li, Rong; Jooss, Natalie J.; Benlabiod, Camelia; Murphy, Eleanor; Etzioni, Zohar; Shepherd, Emelie; Denly, Lucy; Biswas, Sujata; Chen, Lin; O'Sullivan, Jennifer; Rimmer, Michael P.; Khan, Abdullah O.; Karali, Christina Simoglou; Nasreddin, Nadia; Hitchcock, Ian S.; Koupenova, Milka; Kriaucionis, Skirmantas; Hughes, Jim R.; O'Neill, Eric; Vatish, Manu; Rees, Paul; Leedham, Simon; Desborough, Michael; Mead, Adam J.; Schuster-Bockler, Benjamin; Gregory, Christopher D.; Psaila, Bethan
作者单位：University of Oxford; University of Oxford; University of Oxford; Ludwig Institute for Cancer Research; University of Oxford; University of Edinburgh; Oxford University Hospitals NHS Foundation Trust; University of Oxford; Wellcome Centre for Human Genetics; University of York - UK; University of York - UK; University of Massachusetts System; University of Massachusetts Worcester; UMass Chan Medical School; University of Oxford; Swansea University; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
摘要：Platelets are anucleate blood cells vital for hemostasis and immunity. During cell death and aberrant mitosis, nucleated cells release DNA, resulting in cell-free DNA in plasma (cfDNA). An excess of cfDNA is deleterious. Given their ability to internalize pathogen-derived nucleic acids, we hypothesized that platelets may also clear endogenous cfDNA. We found that, despite lacking a nucleus, platelets contained a repertoire of DNA fragments mapping across the nuclear genome. We detected fetal D...
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作者：Xayachak, Tu; Haque, Nawshad; Pramanik, Biplob Kumar
作者单位：Royal Melbourne Institute of Technology (RMIT); Commonwealth Scientific & Industrial Research Organisation (CSIRO)
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作者：Kanitz, Carina; Buehler, Jakob; Zobac, Vladimir; Robinson, Joseph J.; Susi, Toma; Debiossac, Maxime; Brand, Christian
作者单位：Helmholtz Association; German Aerospace Centre (DLR); University of Vienna
摘要：Diffraction of atoms from surfaces provides detailed insights into structures, interactions, and dynamical processes. However, the method is currently limited to measurements in reflection-diffraction through materials has only been demonstrated for subatomic particles and is an outstanding challenge for atoms. In this work, we diffract helium and hydrogen atoms at kilo-electron volt energies through single-layer graphene at normal incidence. Despite the atoms' high kinetic energy as well as c...
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作者：Mann, Adam
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作者：Mervis, Jeffrey
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作者：Silverman, Michael; Knoop, Kathryn
作者单位：University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; University of Pennsylvania; Mayo Clinic
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作者：Kim, Minju; Zhang, Mingyue; Zhu, You-Liang; Yan, Yan; Pu, Xin; Choi, Woosung; Chung, Sein; Cho, Kilwon; Kim, Jeongwon; Tsukruk, Vladimir; Yang, Zhenzhong; Kotov, Nicholas A.; Lu, Zhong-Yuan; Kim, Dong Ha; Lin, Zhiqun
作者单位：National University of Singapore; Ewha Womans University; Jilin University; Anhui University of Technology; University System of Georgia; Georgia Institute of Technology; Pohang University of Science & Technology (POSTECH); Tsinghua University; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan; Ewha Womans University; Ewha Womans University; Ewha Womans University; Ewha Womans University
摘要：Supramolecular assemblies hold great promise for advanced chiral materials because of their structural diversity and dynamic features, but their low chiroptical activity limits practical applications. We report hierarchical supramolecular assemblies with giant chiroptical activity and mechanical attributes achieved through coassembly of achiral amphiphilic unimolecular micelles and chiral additives. Chiral fibrillar assemblies emerge from the nanostructured environment imposed by the micelles,...
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作者：Krammer, Sorin M. S.
作者单位：University of Southampton
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作者：Mabalay, Adrian A.
作者单位：De La Salle University
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作者：Tanaka, Ryoya; Hara, Yusuke; Sato, Kosei; Kohatsu, Soh; Murakami, Hinata; Higuchi, Tomohiro; Awasaki, Takeshi; Kondo, Shu; Toyoda, Atsushi; Kamikouchi, Azusa; Yamamoto, Daisuke
作者单位：Nagoya University; National Institute of Information & Communications Technology (NICT) - Japan; Tohoku University; Kyorin University; Tokyo University of Science; Research Organization of Information & Systems (ROIS); National Institute of Genetics (NIG) - Japan
摘要：In accepting a courting male, Drosophila subobscura females require nuptial gift giving in which a male gives regurgitated crop contents to her mouth to mouth. No similar behavior is found in D. melanogaster. By clonal activation of neurons expressing the male-determinant FruM, we identified insulin-like peptide-producing cells (IPCs) and their putative postsynaptic targets, proboscis-innervating motoneurons, as those critical for gift giving. We demonstrate that loss of FruM from D. subobscur...
