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作者：Seczynska, Marta; Steinmetz, Lars M.
作者单位：Stanford University; Stanford University; European Molecular Biology Laboratory (EMBL)
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作者：Liu, Andrew W.; Zhang, Youran R.; Chen, Chien-Sin; Edwards, Tara N.; Ozyaman, Sumeyye; Ramcke, Torben; McKendrick, Lindsay M.; Weiss, Eric S.; Gillis, Jacob E.; Laughlin, Colin R.; Randhawa, Simran K.; Phelps, Catherine M.; Kurihara, Kazuo; Kang, Hannah M.; Nguyen, Sydney-Lam N.; Kim, Jiwon; Sheahan, Tayler D.; Ross, Sarah E.; Meisel, Marlies; Sumpter, Tina L.; Kaplan, Daniel H.
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Istanbul Medipol University; Yale University; Medical College of Wisconsin
摘要：Itch is a dominant symptom in dermatitis, and scratching promotes cutaneous inflammation, thereby worsening disease. However, the mechanisms through which scratching exacerbates inflammation and whether scratching provides benefit to the host are largely unknown. We found that scratching was required for skin inflammation in mouse models dependent on Fc epsilon RI-mediated mast cell activation. Scratching-induced inflammation required pain-sensing nociceptors, the neuropeptide substance P, and...
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作者：Mervis, Jeffrey
摘要：Move would ban data collection on transgender and nonbinary people
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作者：Campos, Luis A.
作者单位：Rice University; Rice University
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作者：Ray, Saikat; Yona, Itay; Elami, Nadav; Palgi, Shaked; Latimer, Kenneth W.; Jacobsen, Bente; Witter, Menno P.; Las, Liora; Ulanovsky, Nachum
作者单位：Weizmann Institute of Science; University of Chicago; Norwegian University of Science & Technology (NTNU)
摘要：Social animals live in groups and interact volitionally in complex ways. However, little is known about neural responses under such natural conditions. Here, we investigated hippocampal CA1 neurons in a mixed-sex group of five to 10 freely behaving wild Egyptian fruit bats that lived continuously in a laboratory-based cave and formed a stable social network. In-flight, most hippocampal place cells were socially modulated and represented the identity and sex of conspecifics. Upon social interac...
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作者：Kanekiyo, Masaru; Gillespie, Rebecca A.; Cooper, Kristine; Canedo, Vanessa Guerra; Castanha, Priscila M. S.; Pegu, Amarendra; Yang, Eun Sung; Treaster, Luke; Yun, Gabin; Wallace, Megan; Kettenburg, Gwenddolen; Williams, Connor; Lundy, Jeneveve; Barrick, Stacey; O'Malley, Katherine; Midgett, Morgan; Marti, Michelle M.; Chavva, Hasitha; Corry, Jacqueline; Treat, Benjamin R.; Lipinski, Abby; Batsche, Lucia Ortiz; Creanga, Adrian; Ritter, Isabella; Walker, Reagan; Olsen, Emily; Laughlin, Amanda; Perez, Daniel R.; Mascola, John R.; Boritz, Eli A.; Loo, Yueh-Ming; Blair, Wade; Esser, Mark; Graham, Barney S.; Reed, Douglas S.; Barratt-Boyes, Simon M.
作者单位：National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID); Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University System of Georgia; University of Georgia; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; AstraZeneca; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University of Chicago; University System of Ohio; Ohio State University; St Jude Children's Research Hospital; Baylor College of Medicine; Emory University; Tulane University; University of Hawaii System; Morehouse School of Medicine
摘要：Influenza virus pandemics and seasonal epidemics have claimed countless lives. Recurrent zoonotic spillovers of influenza viruses with pandemic potential underscore the need for effective countermeasures. In this study, we show that pre-exposure prophylaxis with broadly neutralizing antibody (bnAb) MEDI8852 is highly effective in protecting cynomolgus macaques from severe disease caused by aerosolized highly pathogenic avian influenza H5N1 virus infection. Protection was antibody dose-dependen...
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作者：Takigawa, Masahiro; Bendor, Daniel
作者单位：University of London; University College London
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作者：Thorp, H. Holden
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作者：[Anonymous]
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作者：Cho, Adrian
摘要：Encouraging lab results bolster plans to harness a new kind of particle accelerator in x-ray sources
