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作者：Koundouros, Nikos; Nagiec, Michal J.; Bullen, Nayah; Noch, Evan K.; Burgos-Barragan, Guillermo; Li, Zhongchi; He, Long; Cho, Sungyun; Parang, Bobak; Leone, Dominique; Andreopoulou, Eleni; Blenis, John
作者单位：Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; NewYork-Presbyterian Hospital; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; University of Texas System; University of Texas Southwestern Medical Center
摘要：Diet influences macronutrient availability to cells, and although mechanisms of sensing dietary glucose and amino acids are well characterized, less is known about sensing lipids. We defined a nutrient signaling mechanism involving fatty acid-binding protein 5 (FABP5) and mechanistic target of rapamycin complex 1 (mTORC1) that is activated by the essential polyunsaturated fatty acid (PUFA) omega-6 linoleic acid (LA). FABP5 directly bound to the regulatory-associated protein of mTOR (Raptor) to...
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作者：Nabavi, Ehsan; Hardcastle, Faranak; Leach, Joan; Medvecky, Fabien; Mckinnon, Merryn; Raman, Sujatha; Santos, Dan
作者单位：Australian National University
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作者：Brainard, Jeffrey
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作者：Li, Ruoshuang; D'Alba, Liliana; Debruyn, Gerben; Dobson, Jessica L.; Zhou, Chang-Fu; Clarke, Julia A.; Vinther, Jakob; Li, Quanguo; Shawkey, Matthew D.
作者单位：China University of Geosciences; Naturalis Biodiversity Center; Ghent University; Shandong University of Science & Technology; Shenyang Normal University; University of Texas System; University of Texas Austin; University of Bristol
摘要：Pelage coloration, which serves numerous functions, is crucial to the evolution of behavior, physiology, and habitat preferences of mammals. However, little is known about the coloration of Mesozoic mammaliaforms that coevolved with dinosaurs. In this study, we used a dataset of melanosome (melanin-containing organelle) morphology and quantitatively measured hair colors from 116 extant mammals to reliably reconstruct the coloration of six Mesozoic mammaliaforms, including a previously undescri...
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作者：Rashid, Muhammed
作者单位：Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Bombay
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作者：Shumilova, O.; Sukhodolov, A.; Osadcha, N.; Oreshchenko, A.; Constantinescu, G.; Afanasyev, S.; Koken, M.; Osadchyi, V.; Rhoads, B.; Tockner, K.; Monaghan, M. T.; Schroeder, B.; Nabyvanets, J.; Wolter, C.; Lietytska, O.; van de Koppel, J.; Magas, N.; Jaehnig, S. C.; Lakisova, V.; Trokhymenko, G.; Venohr, M.; Komorin, V.; Stepanenko, S.; Khilchevskyi, V.; Domisch, S.; Blettler, M.; Gleick, P.; De Meester, L.; Grossart, H. -P.
作者单位：Leibniz Association; Leibniz Institut fur Gewasserokologie und Binnenfischerei (IGB); Leibniz Association; Leibniz Institut fur Gewasserokologie und Binnenfischerei (IGB); National Academy of Sciences Ukraine; Ukrainian Hydrometeorological Institute of the State Emergency Service of Ukraine & National Academy of Sciences of Ukraine; National Academy of Sciences Ukraine; University of Iowa; University of Iowa; National Academy of Sciences Ukraine; Institute of Hydrobiology of the National Academy of Sciences of Ukraine; Middle East Technical University; University of Illinois System; University of Illinois Urbana-Champaign; Goethe University Frankfurt; Free University of Berlin; Technical University of Berlin; Leibniz Association; Leibniz Institut fur Gewasserokologie und Binnenfischerei (IGB); University of Groningen; Ministry of Education & Science of Ukraine; Admiral Makarov National University of Shipbuilding; Leibniz Association; Leibniz Institut fur Gewasserokologie und Binnenfischerei (IGB); Humboldt University of Berlin; Ukrainian Scientific Center of Ecology of the Sea (UkrSCES); Ministry of Education & Science of Ukraine; Odessa State Environmental University; Ministry of Education & Science of Ukraine; Taras Shevchenko National University of Kyiv; KU Leuven; Leibniz Association; Leibniz Institut fur Gewasserokologie und Binnenfischerei (IGB); University of Potsdam
摘要：The use of water as a weapon in highly industrialized areas in the Russo-Ukrainian war has resulted in catastrophic economic and environmental damages. We analyze environmental effects caused by the military destruction of the Kakhovka Dam. We link field, remote sensing, and modeling data to demarcate the disaster's spatial-temporal scales and outline trends in reestablishment of damaged ecosystems. Although media attention has focused on the immediate impacts of flooding on society, politics,...
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作者：Costello, Thomas H.; Pennycook, Gordon; Rand, David G.
作者单位：American University; Massachusetts Institute of Technology (MIT); Cornell University
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作者：Olivier, Wesley J.; Blyszczyk, Piotr; Arpa, Enrique M.; Hitoshio, Kenshiro; Gomez-Mendoza, Miguel; O'shea, Victor de la Pena; Marchand, Isabelle; Poisson, Thomas; Ruffoni, Alessandro; Leonori, Daniele
作者单位：RWTH Aachen University; IMDEA Energy; Centre National de la Recherche Scientifique (CNRS); Universite de Rouen Normandie; University of Kiel
摘要：The ozonolytic deconstruction of aromatics remains a challenge in organic chemistry. Ozone preferentially reacts with alkenes over arenes, meaning that once the initial aromatic cleavage occurs, the dearomatized products are inherently more reactive than the starting materials. Consequently, the process cannot be halted, resulting in full oxidation. Addressing this challenge requires subverting intrinsic rules of chemoselectivity to transform a less reactive substrate in the presence of a more...
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作者：Zhang, Xiangyu; Green, Gregory M.
作者单位：Max Planck Society
摘要：Interstellar dust grains cause extinction (absorption and scattering) of light from background astronomical sources. The spectral shape of the extinction curve depends on the dust composition. We used low-resolution optical spectra to measure the extinction curve of 130 million stars. By inverting these data, we mapped the extinction curve parameter R(V) within the Milky Way in three dimensions and within the Magellanic Clouds in two dimensions. These maps provide improved extinction correctio...
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作者：Moutinho, Sofia
