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作者：Castelvecchi, Davide
摘要：Observatories, experiments and techniques are being developed to spot ripples in space-time at frequencies that currently can't be detected.
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作者：Jon, WooJung
作者单位：Korea Advanced Institute of Science & Technology (KAIST)
摘要：As science becomes more globalized, researchers must safeguard sensitive data from inadvertent legal breaches.
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作者：Lindeboom, Rik G. H.; Worlock, Kaylee B.; Dratva, Lisa M.; Yoshida, Masahiro; Scobie, David; Wagstaffe, Helen R.; Richardson, Laura; Wilbrey-Clark, Anna; Barnes, Josephine L.; Kretschmer, Lorenz; Polanski, Krzysztof; Allen-Hyttinen, Jessica; Mehta, Puja; Sumanaweera, Dinithi; Boccacino, Jacqueline M.; Sungnak, Waradon; Elmentaite, Rasa; Huang, Ni; Mamanova, Lira; Kapuge, Rakesh; Bolt, Liam; Prigmore, Elena; Killingley, Ben; Kalinova, Mariya; Mayer, Maria; Boyers, Alison; Mann, Alex; Swadling, Leo; Woodall, Maximillian N. J.; Ellis, Samuel; Smith, Claire M.; Teixeira, Vitor H.; Janes, Sam M.; Chambers, Rachel C.; Haniffa, Muzlifah; Catchpole, Andrew; Heyderman, Robert; Noursadeghi, Mahdad; Chain, Benny; Mayer, Andreas; Meyer, Kerstin B.; Chiu, Christopher; Nikolic, Marko Z.; Teichmann, Sarah A.
作者单位：Wellcome Trust Sanger Institute; Netherlands Cancer Institute; University of London; University College London; University of London; University College London; Imperial College London; Mahidol University; Mahidol University; University of London; University College London; University College London Hospitals NHS Foundation Trust; University of London; University College London; University of London; University College London; University of Cambridge; University of Cambridge
摘要：The COVID-19 pandemic is an ongoing global health threat, yet our understanding of the dynamics of early cellular responses to this disease remains limited 1 . Here in our SARS-CoV-2 human challenge study, we used single-cell multi-omics profiling of nasopharyngeal swabs and blood to temporally resolve abortive, transient and sustained infections in seronegative individuals challenged with pre-Alpha SARS-CoV-2. Our analyses revealed rapid changes in cell-type proportions and dozens of highly d...
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作者：Pearson, R. A.; Barber, A. C.; Rizzi, M.; Hippert, C.; Xue, T.; West, E. L.; Duran, Y.; Smith, A. J.; Chuang, J. Z.; Azam, S. A.; Luhmann, U. F. O.; Benucci, A.; Sung, C. H.; Bainbridge, J. W.; Carandini, M.; Yau, K. -W.; Sowden, J. C.; Ali, R. R.
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作者：Mahat, Dig B.; Tippens, Nathaniel D.; Martin-Rufino, Jorge D.; Waterton, Sean K.; Fu, Jiayu; Blatt, Sarah E.; Sharp, Phillip A.
作者单位：Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Stanford University; Northwestern University
摘要：Transcription is the primary regulatory step in gene expression. Divergent transcription initiation from promoters and enhancers produces stable RNAs from genes and unstable RNAs from enhancers(1,2). Nascent RNA capture and sequencing assays simultaneously measure gene and enhancer activity in cell populations(3). However, fundamental questions about the temporal regulation of transcription and enhancer-gene coordination remain unanswered, primarily because of the absence of a single-cell pers...
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作者：Wang, Jia; Cai, Wentao; Lu, Weifang; Lu, Shun; Kano, Emi; Agulto, Verdad C.; Sarkar, Biplab; Watanabe, Hirotaka; Ikarashi, Nobuyuki; Iwamoto, Toshiyuki; Nakajima, Makoto; Honda, Yoshio; Amano, Hiroshi
作者单位：Nagoya University; Nagoya University; Meijo University; Nagoya University; University of Osaka; Xiamen University; Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Roorkee
摘要：Since the demonstration of p-type gallium nitride (GaN) through doping with substitutional magnesium (Mg) atoms(1,2), rapid and comprehensive developments, such as blue light-emitting diodes, have considerably shaped our modern lives and contributed to a more carbon-neutral society(3-5). However, the details of the interplay between GaN and Mg have remained largely unknown(6-11). Here we observe that Mg-intercalated GaN superlattices can form spontaneously by annealing a metallic Mg film on Ga...
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作者：McNamara, Patrick; Newsome, William; Linkenhoker, Brie; Grafman, Jordan
作者单位：National University (California); Boston University; Stanford University; Northwestern University; Feinberg School of Medicine; Shirley Ryan AbilityLab
摘要：Scientists interested in the brain have tended to avoid studying religion or spirituality for fear of being seen as unscientific. That needs to change.
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作者：Read, Katie A.; Mahajan, Anoop S.; Carpenter, Lucy J.; Evans, Mathew J.; Faria, Bruno V. E.; Heard, Dwayne E.; Hopkins, James R.; Lee, James D.; Moller, Sarah J.; Lewis, Alastair C.; Mendes, Luis; McQuaid, James B.; Oetjen, Hilke; Saiz-Lopez, Alfonso; Pilling, Michael J.; Plane, John M. C.
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作者：Bhaduri, Aparna
作者单位：University of California System; University of California Los Angeles
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作者：Xing, Yuqing; Bae, Seokjin; Ritz, Ethan; Yang, Fan; Birol, Turan; Salinas, Andrea N. Capa; Ortiz, Brenden R.; Wilson, Stephen D.; Wang, Ziqiang; Fernandes, Rafael M.; Madhavan, Vidya
作者单位：University of Illinois System; University of Illinois Urbana-Champaign; University of Illinois System; University of Illinois Urbana-Champaign; University of Minnesota System; University of Minnesota Twin Cities; University of California System; University of California Santa Barbara; Boston College; University of Minnesota System; University of Minnesota Twin Cities
摘要：Broken time-reversal symmetry in the absence of spin order indicates the presence of unusual phases such as orbital magnetism and loop currents(1-4). The recently discovered kagome superconductors AV(3)Sb(5) (where A is K, Rb or Cs)(5,6) display an exotic charge-density-wave (CDW) state and have emerged as a strong candidate for materials hosting a loop current phase. The idea that the CDW breaks time-reversal symmetry(7-14) is, however, being intensely debated due to conflicting experimental ...
