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作者：Blackie, Laura; Gaspar, Pedro; Mosleh, Salem; Lushchak, Oleh; Kong, Lingjin; Jin, Yuhong; Zielinska, Agata P.; Cao, Boxuan; Mineo, Alessandro; Silva, Bryon; Ameku, Tomotsune; Lim, Shu En; Mao, Yanlan; Prieto-Godino, Lucia; Schoborg, Todd; Varela, Marta; Mahadevan, L.; Miguel-Aliaga, Irene
作者单位：Imperial College London; Francis Crick Institute; Harvard University; MRC Laboratory Molecular Biology; University of London; University College London; University of London; University College London; University of Wyoming; Imperial College London; Harvard University; University System of Maryland; University of Maryland Eastern Shore
摘要：Organs have a distinctive yet often overlooked spatial arrangement in the body(1-5). We propose that there is a logic to the shape of an organ and its proximity to its neighbours. Here, by using volumetric scans of many Drosophila melanogaster flies, we develop methods to quantify three-dimensional features of organ shape, position and interindividual variability. We find that both the shapes of organs and their relative arrangement are consistent yet differ between the sexes, and identify une...
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作者：Han, Yuling; Duan, Xiaohua; Yang, Liuliu; Nilsson-Payant, Benjamin E.; Wang, Pengfei; Duan, Fuyu; Tang, Xuming; Yaron, Tomer M.; Zhang, Tuo; Uhl, Skyler; Bram, Yaron; Richardson, Chanel; Zhu, Jiajun; Zhao, Zeping; Redmond, David; Houghton, Sean; Nguyen, Duc-Huy T.; Xu, Dong; Wang, Xing; Jessurun, Jose; Borczuk, Alain; Huang, Yaoxing; Johnson, Jared L.; Liu, Yuru; Xiang, Jenny; Wang, Hui; Cantley, Lewis C.; tenOever, Benjamin R.; Ho, David D.; Pan, Fong Cheng; Evans, Todd; Chen, Huanhuan Joyce; Schwartz, Robert E.; Chen, Shuibing
作者单位：Cornell University; Weill Cornell Medicine; Shanghai Jiao Tong University; Icahn School of Medicine at Mount Sinai; Columbia University; University of Chicago; University of Chicago; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital; Cornell University; Weill Cornell Medicine
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作者：Steinmetz, Michael; Minard, Karyl; Horvath, Suzanna; McNicholast, Janet; Frelinger, Jeffrey; Wake, Claire; Long, Eric; Mach, Bernard; Hood, Leroy
作者单位：California Institute of Technology; Stanford University; University of Southern California; University of Geneva
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作者：Lu, Donglin; Chen, Yang; Lu, Zheyi; Ma, Likuan; Tao, Quanyang; Li, Zhiwei; Kong, Lingan; Liu, Liting; Yang, Xiaokun; Ding, Shuimei; Liu, Xiao; Li, Yunxin; Wu, Ruixia; Wang, Yiliu; Hu, Yuanyuan; Duan, Xidong; Liao, Lei; Liu, Yuan
作者单位：Hunan University; Hunan University; Hunan University
摘要：Two-dimensional (2D) semiconductors have shown great potential for monolithic three-dimensional (M3D) integration due to their dangling-bonds-free surface and the ability to integrate to various substrates without the conventional constraint of lattice matching(1-10). However, with atomically thin body thickness, 2D semiconductors are not compatible with various high-energy processes in microelectronics(11-13), where the M3D integration of multiple 2D circuit tiers is challenging. Here we repo...
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作者：Andrade, Rodrigo de Oliveira
摘要：The total number of individuals entering master's and doctoral programmes dropped 12% between 2019 and 2022, reaching the lowest level in nearly a decade.
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作者：Lenharo, Mariana
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作者：Watanabe, Masahiro; Kang, Sarah M.; Collins, Matthew; Hwang, Yen-Ting; McGregor, Shayne; Stuecker, Malte F.
作者单位：University of Tokyo; Max Planck Society; University of Exeter; National Taiwan University; Monash University; University of Hawaii System; University of Hawaii Manoa; University of Hawaii System; University of Hawaii Manoa
摘要：Changes in the sea surface temperature (SST) pattern in the tropical Pacific modulate radiative feedbacks to greenhouse gas forcing, the pace of global warming and regional climate impacts. Therefore, elucidating the drivers of the pattern is critically important for reducing uncertainties in future projections. However, the causes of observed changes over recent decades, an enhancement of the zonal SST contrast coupled with a strengthening of the Walker circulation, are still debated. Here we...
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作者：[Anonymous]
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作者：Byrns, China N.; Perlegos, Alexandra E.; Miller, Karl N.; Jin, Zhecheng; Carranza, Faith R.; Manchandra, Palak; Beveridge, Connor H.; Randolph, Caitlin E.; Chaluvadi, V. Sai; Zhang, Shirley L.; Srinivasan, Ananth R.; Bennett, F. C.; Sehgal, Amita; Adams, Peter D.; Chopra, Gaurav; Bonini, Nancy M.
作者单位：University of Pennsylvania; University of Pennsylvania; University of Pennsylvania; Sanford Burnham Prebys Medical Discovery Institute; Purdue University System; Purdue University; University of Pennsylvania; Howard Hughes Medical Institute; University of Pennsylvania; University of Pennsylvania; University of Pennsylvania; Pennsylvania Medicine; Childrens Hospital of Philadelphia; Purdue University System; Purdue University; Purdue University System; Purdue University; Purdue University System; Purdue University; Purdue University System; Purdue University
摘要：Senescence is a cellular state linked to ageing and age-onset disease across many mammalian species(1,2). Acutely, senescent cells promote wound healing(3,4) and prevent tumour formation5; but they are also pro-inflammatory, thus chronically exacerbate tissue decline. Whereas senescent cells are active targets for anti-ageing therapy(6-11), why these cells form in vivo, how they affect tissue ageing and the effect of their elimination remain unclear(12,13). Here we identify naturally occurring...
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作者：Elvidge, Sean
作者单位：University of Birmingham
摘要：Categorizing geomagnetic storms on a scale of one to five leaves no room for once-a-century superstorms.
