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作者:Pyle, Charlie J.; Tobin, David M.
作者单位:Duke University; Duke University
摘要:The immune-signalling protein TNF has an essential role in inflammatory responses. Two people who were found to have no functional TNF are surprisingly healthy and able to fend off most infections, but are susceptible to tuberculosis.
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作者:[Anonymous]
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作者:Reardon, Sara
摘要:The disease has a consistent mark in the brain even when symptoms are absent.
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作者:Chen, Jianwei; Jia, Yangyang; Sun, Ying; Liu, Kun; Zhou, Changhao; Liu, Chuan; Li, Denghui; Liu, Guilin; Zhang, Chengsong; Yang, Tao; Huang, Lei; Zhuang, Yunyun; Wang, Dazhi; Xu, Dayou; Zhong, Qiaoling; Guo, Yang; Li, Anduo; Seim, Inge; Jiang, Ling; Wang, Lushan; Lee, Simon Ming Yuen; Liu, Yujing; Wang, Dantong; Zhang, Guoqiang; Liu, Shanshan; Wei, Xiaofeng; Yue, Zhen; Zheng, Shanmin; Shen, Xuechun; Wang, Sen; Qi, Chen; Chen, Jing; Ye, Chen; Zhao, Fang; Wang, Jun; Fan, Jie; Li, Baitao; Sun, Jiahui; Jia, Xiaodong; Xia, Zhangyong; Zhang, He; Liu, Junnian; Zheng, Yue; Liu, Xin; Wang, Jian; Yang, Huanming; Kristiansen, Karsten; Xu, Xun; Mock, Thomas; Li, Shengying; Zhang, Wenwei; Fan, Guangyi
作者单位:Beijing Genomics Institute (BGI); University of Copenhagen; Shandong University; Beijing Genomics Institute (BGI); Ocean University of China; Xiamen University; Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Deep-Sea Science & Engineering, CAS; Nanjing Tech University; Hong Kong Polytechnic University; Hong Kong Polytechnic University; Beijing Genomics Institute (BGI); University of East Anglia
摘要:The past two decades has witnessed a remarkable increase in the number of microbial genomes retrieved from marine systems1,2. However, it has remained challenging to translate this marine genomic diversity into biotechnological and biomedical applications3,4. Here we recovered 43,191 bacterial and archaeal genomes from publicly available marine metagenomes, encompassing a wide range of diversity with 138 distinct phyla, redefining the upper limit of marine bacterial genome size and revealing c...
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作者:Liu, Cheng; Yang, Yi; Chen, Hao; Spanopoulos, Ioannis; Bati, Abdulaziz S. R.; Gilley, Isaiah W.; Chen, Jianhua; Maxwell, Aidan; Vishal, Badri; Reynolds, Robert P.; Wiggins, Taylor E.; Wang, Zaiwei; Huang, Chuying; Fletcher, Jared; Liu, Yuan; Chen, Lin X.; De Wolf, Stefaan; Chen, Bin; Zheng, Ding; Marks, Tobin J.; Facchetti, Antonio; Sargent, Edward H.; Kanatzidis, Mercouri G.
作者单位:Northwestern University; State University System of Florida; University of South Florida; University of Toronto; King Abdullah University of Science & Technology; Northwestern University; University System of Georgia; Georgia Institute of Technology
摘要:Two-dimensional (2D) and three-dimensional (3D) perovskite heterostructures have played a key role in advancing the performance of perovskite solar cells1,2. However, the migration of cations between 2D and 3D layers results in the disruption of octahedral networks, leading to degradation in performance over time3,4. We hypothesized that perovskitoids, with robust organic-inorganic networks enabled by edge- and face-sharing, could impede ion migration. We explored a set of perovskitoids of var...
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作者:Yang, Bo; Zhao, Zunlian
作者单位:Changsha University; State Grid Corporation of China
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作者:[Anonymous]
摘要:Fossils hint that bats' wings sometimes lodged in fish's throats, leading the bat-eater to die of hunger.
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作者:Stewart, Katherine S.; Abdusselamoglu, Merve Deniz; Tierney, Matthew T.; Gola, Anita; Hur, Yun Ha; Gonzales, Kevin A. U.; Yuan, Shaopeng; Bonny, Alain R.; Yang, Yihao; Infarinato, Nicole R.; Cowley, Christopher J.; Levorse, John M.; Pasolli, Hilda Amalia; Ghosh, Sourav; Rothlin, Carla V.; Fuchs, Elaine
作者单位:Howard Hughes Medical Institute; Rockefeller University; Rockefeller University; Yale University; Yale University; Pohang University of Science & Technology (POSTECH); Memorial Sloan Kettering Cancer Center; Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple University
摘要:Billions of cells are eliminated daily from our bodies(1-4). Although macrophages and dendritic cells are dedicated to migrating and engulfing dying cells and debris, many epithelial and mesenchymal tissue cells can digest nearby apoptotic corpses(1-4). How these non-motile, non-professional phagocytes sense and eliminate dying cells while maintaining their normal tissue functions is unclear. Here we explore the mechanisms that underlie their multifunctionality by exploiting the cyclical bouts...
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作者:Cernak, Tim
作者单位:University of Michigan System; University of Michigan
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作者:Mallapaty, Smriti