8038期

最新文章

• Targeting immune-fibroblast cell communication in heart failure AI翻译
  作者：Amrute, Junedh M.; Luo, Xin; Penna, Vinay; Yang, Steven; Yamawaki, Tracy; Hayat, Sikander; Bredemeyer, Andrea; Jung, In-Hyuk; Kadyrov, Farid F.; Heo, Gyu Seong; Venkatesan, Rajiu; Shi, Sally Yu; Parvathaneni, Alekhya; Koenig, Andrew L.; Kuppe, Christoph; Baker, Candice; Luehmann, Hannah; Jones, Cameran; Kopecky, Benjamin; Zeng, Xue; Bleckwehl, Tore; Ma, Pan; Lee, Paul; Terada, Yuriko; Fu, Angela; Furtado, Milena; Kreisel, Daniel; Kovacs, Atilla; Stitziel, Nathan O.; Jackson, Simon; Li, Chi-Ming; Liu, Yongjian; Rosenthal, Nadia A.; Kramann, Rafael; Ason, Brandon; Lavine, Kory J.
  作者单位：Washington University (WUSTL); Amgen; RWTH Aachen University; Washington University (WUSTL); RWTH Aachen University; Jackson Laboratory; Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); Washington University (WUSTL); Erasmus University Rotterdam; Erasmus MC; Washington University (WUSTL)
  摘要：Inflammation and tissue fibrosis co-exist and are causally linked to organ dysfunction1,2. However, the molecular mechanisms driving immune-fibroblast cell communication in human cardiac disease remain unexplored and there are at present no approved treatments that directly target cardiac fibrosis3,4. Here we performed multiomic single-cell gene expression, epitope mapping and chromatin accessibility profiling in 45 healthy donor, acutely infarcted and chronically failing human hearts. We iden...
• Inducing novel endosymbioses by implanting bacteria in fungi AI翻译
  作者：Giger, Gabriel H.; Ernst, Chantal; Richter, Ingrid; Gassler, Thomas; Field, Christopher M.; Sintsova, Anna; Kiefer, Patrick; Gaebelein, Christoph G.; Guillaume-Gentil, Orane; Scherlach, Kirstin; Bortfeld-Miller, Miriam; Zambelli, Tomaso; Sunagawa, Shinichi; Kunzler, Markus; Hertweck, Christian; Vorholt, Julia A.
  作者单位：Swiss Federal Institutes of Technology Domain; ETH Zurich; Leibniz Association; Hans Knoll Institute (HKI); Swiss Federal Institutes of Technology Domain; ETH Zurich; Friedrich Schiller University of Jena; Friedrich Schiller University of Jena; Massachusetts Institute of Technology (MIT); Whitehead Institute
  摘要：Endosymbioses have profoundly impacted the evolution of life and continue to shape the ecology of a wide range of species. They give rise to new combinations of biochemical capabilities that promote innovation and diversification(1,2). Despite the many examples of known endosymbioses across the tree of life, their de novo emergence is rare and challenging to uncover in retrospect(3-5). Here we implant bacteria into the filamentous fungus Rhizopus microsporus to follow the fate of artificially ...
• Why did Earth's first radio message to alien civilizations leave out half of humanity? AI翻译
  作者：Charbonneau, Rebecca
• The black hole low-mass X-ray binary V404 Cygni is part of a wide triple AI翻译
  作者：Burdge, Kevin B.; El-Badry, Kareem; Kara, Erin; Canizares, Claude; Chakrabarty, Deepto; Frebel, Anna; Millholland, Sarah C.; Rappaport, Saul; Simcoe, Rob; Vanderburg, Andrew
  作者单位：Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); California Institute of Technology
  摘要：Evidence suggests that, when compact objects such as black holes and neutron stars form, they may receive a 'natal kick', during which the stellar remnant gains momentum. Observational evidence for neutron star kicks is substantial1,2, yet is limited for black hole natal kicks, and some proposed black hole formation scenarios result in very small kicks3-5. Here we report that the canonical black hole low-mass X-ray binary (LMXB) V404 Cygni is part of a wide hierarchical triple with a tertiary ...
• Devastating Spanish floods expose an urgent need for more flood-risk professionals AI翻译
  作者：Piccolroaz, Sebastiano
  作者单位：University of Trento
• How I'm turning seaweed into biofuel for cars on Barbados AI翻译
  作者：Powell, Kendall
  摘要：Mechanical engineer Legena Henry converts sargassum and rum-distillery waste water to produce sustainable natural gas for vehicles.
• ChatGPT and the Future of AI: The Deep Language Revolution AI翻译
  作者：Tagarro, Pablo M.
• The world's oldest tree? Genetic analysis traces evolution of iconic Pando forest AI翻译
  作者：Kudiabor, Helena
• Charge-neutral electronic excitations in quantum insulators AI翻译
  作者：Wu, Sanfeng; Schoop, Leslie M.; Sodemann, Inti; Moessner, Roderich; Cava, Robert J.; Ong, N. P.
  作者单位：Princeton University; Princeton University; Leipzig University; Max Planck Society
  摘要：Experiments on quantum materials have uncovered many interesting quantum phases ranging from superconductivity to a variety of topological quantum matter including the recently observed fractional quantum anomalous Hall insulators. The findings have come in parallel with the development of approaches to probe the rich excitations inherent in such systems. In contrast to observing electrically charged excitations, the detection of charge-neutral electronic excitations in condensed matter remain...
• Accelerated formation of ultra-massive galaxies in the first billion years AI翻译
  作者：Xiao, Mengyuan; Oesch, Pascal A.; Elbaz, David; Bing, Longji; Nelson, Erica J.; Weibel, Andrea; Illingworth, Garth D.; van Dokkum, Pieter; Naidu, Rohan P.; Daddi, Emanuele; Bouwens, Rychard J.; Matthee, Jorryt; Wuyts, Stijn; Chisholm, John; Brammer, Gabriel; Dickinson, Mark; Magnelli, Benjamin; Leroy, Lucas; Schaerer, Daniel; Herard-Demanche, Thomas; Lim, Seunghwan; Barrufet, Laia; Endsley, Ryan; Fudamoto, Yoshinobu; Gomez-Guijarro, Carlos; Gottumukkala, Rashmi; Labbe, Ivo; Magee, Dan; Marchesini, Danilo; Maseda, Michael; Qin, Yuxiang; Reddy, Naveen A.; Shapley, Alice; Shivaei, Irene; Shuntov, Marko; Stefanon, Mauro; Whitaker, Katherine E.; Wyithe, J. Stuart B.
  作者单位：University of Geneva; University of Copenhagen; Niels Bohr Institute; Universite Paris Saclay; CEA; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; University of Sussex; University of Colorado System; University of Colorado Boulder; University of California System; University of California Santa Cruz; Yale University; Massachusetts Institute of Technology (MIT); Leiden University; Leiden University - Excl LUMC; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Bath; University of Texas System; University of Texas Austin; University of Cambridge; University of Cambridge; Waseda University; National Institutes of Natural Sciences (NINS) - Japan; National Astronomical Observatory of Japan (NAOJ); Swinburne University of Technology; Tufts University; University of Wisconsin System; University of Wisconsin Madison; University of Melbourne; University of California System; University of California Riverside; University of California System; University of California Los Angeles; University of Arizona; University of Valencia; Consejo Superior de Investigaciones Cientificas (CSIC); Universidad de Cantabria; CSIC - Instituto de Fisica de Cantabria (IFCA); University of Valencia; University of Massachusetts System; University of Massachusetts Amherst
  摘要：Recent James Webb Space Telescope (JWST) observations have revealed an unexpected abundance of massive-galaxy candidates in the early Universe, extending further in redshift and to lower luminosity than what had previously been found by submillimetre surveys1-6. These JWST candidates have been interpreted as challenging the Lambda cold dark-matter cosmology (where Lambda is the cosmological constant)7-9, but, so far, these studies have mostly relied on only rest-frame ultraviolet data and have...