作者：Ng, Christine S. C.; Liu, Aofei; Cui, Bianxiao; Banik, Steven M.
作者单位：Stanford University; Stanford University
摘要：Subcellular protein localization regulates protein function and can be corrupted in cancers(1) and neurodegenerative diseases(2,3). The rewiring of localization to address disease-driving phenotypes would be an attractive targeted therapeutic approach. Molecules that harness the trafficking of a shuttle protein to control the subcellular localization of a target protein could enforce targeted protein relocalization and rewire the interactome. Here we identify a collection of shuttle proteins w...
作者：Dickopf, Stefan; Sikora, Bastian; Kaiser, Annabelle; Mueller, Marius; Ulmer, Stefan; Yerokhin, Vladimir A.; Harman, Zoltan; Keitel, Christoph H.; Mooser, Andreas; Blaum, Klaus
作者：Dolgin, Elie
摘要：Pain is defined subjectively, but an objective measure of the experience promises to transform its management
作者：Garisto, Dan
摘要：Particle measurements at the Large Hadron Collider open the door to future high-energy tests of entanglement. Particle measurements at the Large Hadron Collider open the door to future high-energy tests of entanglement.
作者：Huebner, Stefan
作者单位：National University of Singapore
作者：Owens, Brian
摘要：Industry research funding is vastly eclipsing academia's spend, but healthy development demands broad input.
