-
作者：[Anonymous]
-
作者：Lu, Jun; Wu, Wenbing; Colombari, Felippe Mariano; Jawaid, Ali; Seymour, Bryan; Whisnant, Kody; Zhong, Xiaoyang; Choi, Wonjin; Chalmpes, Nikolaos; Lahann, Joerg; Vaia, Richard A.; de Moura, Andre Farias; Nepal, Dhriti; Kotov, Nicholas A.
作者单位：Cornell University
-
作者：Park, Juhyung; Wu, Jibo; Szkop, Krzysztof J.; Jeong, Jinho; Jovanovic, Predrag; Husmann, Dylan; Flores, Natasha M.; Francis, Joel W.; Chen, Ying-Jiun C.; Benitez, Ana Morales; Zahn, Emily; Song, Shumei; Ajani, Jaffer A.; Wang, Linghua; Singh, Kamini; Larsson, Ola; Garcia, Benjamin A.; Topisirovic, Ivan; Gozani, Or; Mazur, Pawel K.
作者单位：Stanford University; University of Texas System; UTMD Anderson Cancer Center; Karolinska Institutet; Lady Davis Institute; McGill University; McGill University; Washington University (WUSTL); University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center; Montefiore Medical Center; Albert Einstein College of Medicine; Yeshiva University; University of Texas System; UTMD Anderson Cancer Center
摘要：Dysregulated transcription due to disruption in histone lysine methylation dynamics is an established contributor to tumorigenesis(1,2). However, whether analogous pathologic epigenetic mechanisms act directly on the ribosome to advance oncogenesis is unclear. Here we find that trimethylation of the core ribosomal protein L40 (rpL40) at lysine 22 (rpL40K22me3) by the lysine methyltransferase SMYD5 regulates mRNA translation output to promote malignant progression of gastric adenocarcinoma (GAC...
-
作者：Liu, Peng; Panda, Kaushik; Edwards, Seth A.; Swanson, Ryan; Yi, Hochul; Pandesha, Pratheek; Hung, Yu-Hung; Klaas, Gerald; Ye, Xudong; Collins, Megan V.; Renken, Kaili N.; Gilbertson, Larry A.; Veena, Veena; Hancock, C. Nathan; Slotkin, R. Keith
作者单位：Donald Danforth Plant Science Center; University of Missouri System; University of Missouri Columbia; Donald Danforth Plant Science Center; Washington University (WUSTL); Bayer AG; Bayer CropScience
摘要：The current technologies to place new DNA into specific locations in plant genomes are low frequency and error-prone, and this inefficiency hampers genome-editing approaches to develop improved crops1,2. Often considered to be genome 'parasites', transposable elements (TEs) evolved to insert their DNA seamlessly into genomes3-5. Eukaryotic TEs select their site of insertion based on preferences for chromatin contexts, which differ for each TE type6-9. Here we developed a genome engineering too...
-
作者：Zhu, Yinghao; Peng, Di; Zhang, Enkang; Pan, Bingying; Chen, Xu; Chen, Lixing; Ren, Huifen; Liu, Feiyang; Hao, Yiqing; Li, Nana; Xing, Zhenfang; Lan, Fujun; Han, Jiyuan; Wang, Junjie; Jia, Donghan; Wo, Hongliang; Gu, Yiqing; Gu, Yimeng; Ji, Li; Wang, Wenbin; Gou, Huiyang; Shen, Yao; Ying, Tianping; Chen, Xiaolong; Yang, Wenge; Cao, Huibo; Zheng, Changlin; Zeng, Qiaoshi; Guo, Jian-gang; Zhao, Jun
作者单位：Fudan University; Fudan University; Ocean University of China; Chinese Academy of Sciences; Institute of Physics, CAS; United States Department of Energy (DOE); Oak Ridge National Laboratory; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Fudan University; Fudan University
摘要：The pursuit of discovering new high-temperature superconductors that diverge from the copper-based model(1-3) has profound implications for explaining mechanisms behind superconductivity and may also enable new applications(4-8). Here our investigation shows that the application of pressure effectively suppresses the spin-charge order in trilayer nickelate La4Ni3O10-delta single crystals, leading to the emergence of superconductivity with a maximum critical temperature (T-c) of around 30 K at ...
-
作者：Kudiabor, Helena
摘要：Cultured meat that tastes and smells more appetizing could enhance public perception of artificial steaks.
-
作者：Pan, Yude; Birdsey, Richard A.; Phillips, Oliver L.; Houghton, Richard A.; Fang, Jingyun; Kauppi, Pekka E.; Keith, Heather; Kurz, Werner A.; Ito, Akihiko; Lewis, Simon L.; Nabuurs, Gert-Jan; Shvidenko, Anatoly; Hashimoto, Shoji; Lerink, Bas; Schepaschenko, Dmitry; Castanho, Andrea; Murdiyarso, Daniel
作者单位：United States Department of Agriculture (USDA); United States Forest Service; University of Leeds; Peking University; University of Helsinki; Swedish University of Agricultural Sciences; Griffith University; Griffith University - Gold Coast Campus; Natural Resources Canada; Canadian Forest Service; University of Tokyo; University of London; University College London; Wageningen University & Research; Wageningen University & Research; International Institute for Applied Systems Analysis (IIASA); Forestry & Forest Products Research Institute - Japan; Bogor Agricultural University
摘要：The uptake of carbon dioxide (CO2) by terrestrial ecosystems is critical for moderating climate change1. To provide a ground-based long-term assessment of the contribution of forests to terrestrial CO2 uptake, we synthesized in situ forest data from boreal, temperate and tropical biomes spanning three decades. We found that the carbon sink in global forests was steady, at 3.6 +/- 0.4 Pg C yr-1 in the 1990s and 2000s, and 3.5 +/- 0.4 Pg C yr-1 in the 2010s. Despite this global stability, our an...
-
作者：Baltussen, Mathieu G.; de Jong, Thijs J.; Duez, Quentin; Robinson, William E.; Huck, Wilhelm T. S.
作者单位：Radboud University Nijmegen
摘要：Chemical reaction networks, such as those found in metabolism and signalling pathways, enable cells to process information from their environment1,2. Current approaches to molecular information processing and computation typically pursue digital computation models and require extensive molecular-level engineering3. Despite considerable advances, these approaches have not reached the level of information processing capabilities seen in living systems. Here we report on the discovery and impleme...
-
作者：Sidor, Christian A.
作者单位：University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle
-
作者：Bourgoin, C.; Ceccherini, G.; Girardello, M.; Vancutsem, C.; Avitabile, V.; Beck, P. S. A.; Beuchle, R.; Blanc, L.; Duveiller, G.; Migliavacca, M.; Vieilledent, G.; Cescatti, A.; Achard, F.
作者单位：European Commission Joint Research Centre; EC JRC ISPRA Site; CIRAD; CIRAD; Universite de Montpellier; Max Planck Society; CIRAD; Centre National de la Recherche Scientifique (CNRS); Institut de Recherche pour le Developpement (IRD); Universite de Montpellier; Universite de Montpellier; Centre National de la Recherche Scientifique (CNRS); CIRAD
摘要：Tropical forest degradation from selective logging, fire and edge effects is a major driver of carbon and biodiversity loss(1-3), with annual rates comparable to those of deforestation(4). However, its actual extent and long-term impacts remain uncertain at global tropical scale(5). Here we quantify the magnitude and persistence of multiple types of degradation on forest structure by combining satellite remote sensing data on pantropical moist forest cover changes(4) with estimates of canopy h...
