2024

最新文章

• How to design a protein that can be switched on and off AI翻译
  作者：Wand, A. Joshua
  作者单位：Texas A&M University System; Texas A&M University College Station
  摘要：Proteins have been designed that assemble in different ways depending on whether an 'effector' molecule is present - a demonstration of allostery, the phenomenon that enables switch-like control of protein functions in nature. Designer proteins that exhibit the phenomenon of allostery.
• Multimodal approach steps up the search for axion insulators AI翻译
  作者：Ahn, Youngjun; Zhao, Liuyan
  作者单位：University of Michigan System; University of Michigan; United States Department of Energy (DOE); Argonne National Laboratory
  摘要：A cocktail of experiments and theory provides a way of revealing complex patterns in magnetic materials, including some textures that can identify the systems as members of an elusive class known as axion insulators.
• The Great Barrier Reef is warmer than ever AI翻译
  作者：Pfeiffer, Miriam
  作者单位：University of Kiel
• Blood tests could soon predict your risk of Alzheimer's AI翻译
  作者：Abbott, Alison
  摘要：Scientists are closing in on biomarkers that reflect the progression of Alzheimer's disease and could improve treatments.
• Neuroscience is crucial for transgender people's health AI翻译
  作者：VanderLaan, Doug P.; Huepen, Philippa
  作者单位：University of Toronto; University Toronto Mississauga; RWTH Aachen University
• A maternal brain hormone that builds bone AI翻译
  作者：Babey, Muriel E.; Krause, William C.; Chen, Kun; Herber, Candice B.; Torok, Zsofia; Nikkanen, Joni; Rodriguez, Ruben; Zhang, Xiao; Castro-Navarro, Fernanda; Wang, Yuting; Wheeler, Erika E.; Villeda, Saul; Leach, J. Kent; Lane, Nancy E.; Scheller, Erica L.; Chan, Charles K. F.; Ambrosi, Thomas H.; Ingraham, Holly A.
  作者单位：University of California System; University of California San Francisco; University of California System; University of California San Francisco; California State University System; California State University Sacramento; Washington University (WUSTL); Stanford University; Stanford University; University of California System; University of California Davis; University of California System; University of California San Francisco; University of California System; University of California Davis; University of California System; University of California Berkeley
  摘要：In lactating mothers, the high calcium (Ca2+) demand for milk production triggers significant bone loss1. Although oestrogen normally counteracts excessive bone resorption by promoting bone formation, this sex steroid drops precipitously during this postpartum period. Here we report that brain-derived cellular communication network factor 3 (CCN3) secreted from KISS1 neurons of the arcuate nucleus (ARCKISS1) fills this void and functions as a potent osteoanabolic factor to build bone in lactat...
• Catalytic glycosylation for minimally protected donors and acceptors AI翻译
  作者：Dang, Qiu-Di; Deng, Yi-Hui; Sun, Tian-Yu; Zhang, Yao; Li, Jun; Zhang, Xia; Wu, Yun-Dong; Niu, Dawen
  作者单位：Sichuan University; Sichuan University; Peking University Shenzhen Graduate School (PKU Shenzhen); Peking University; Shenzhen Bay Laboratory
  摘要：Oligosaccharides have myriad functions throughout biological processes1,2. Chemical synthesis of these structurally complex molecules facilitates investigation of their functions. With a dense concentration of stereocentres and hydroxyl groups, oligosaccharide assembly through O-glycosylation requires simultaneous control of site, stereo- and chemoselectivities3,4. Chemists have traditionally relied on protecting group manipulations for this purpose5-8, adding considerable synthetic work. Here...
• 'Ocean ranching' has led to a pink-salmon boom - but there might be a catch AI翻译
  作者：Soliman, Alix
  摘要：Unintended interbreeding between hatchery-bred and wild-born pink salmon could reduce resiliency of fish stocks.
• First map of an ice shelf's bottom reveals mysterious melt patterns AI翻译
  作者：Soliman, Alix
  摘要：High-resolution images of the underside of a formation in Antarctica could help researchers to refine projections of sea-level rise.
• Antiferromagnetic phase transition in a 3D fermionic Hubbard model AI翻译
  作者：Shao, Hou-Ji; Wang, Yu-Xuan; Zhu, De-Zhi; Zhu, Yan-Song; Sun, Hao-Nan; Chen, Si-Yuan; Zhang, Chi; Fan, Zhi-Jie; Deng, Youjin; Yao, Xing-Can; Chen, Yu-Ao; Pan, Jian-Wei
  作者单位：Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Hefei National Laboratory; Chinese Academy of Sciences; University of Science & Technology of China, CAS
  摘要：The fermionic Hubbard model (FHM)1 describes a wide range of physical phenomena resulting from strong electron-electron correlations, including conjectured mechanisms for unconventional superconductivity. Resolving its low-temperature physics is, however, challenging theoretically or numerically. Ultracold fermions in optical lattices2,3 provide a clean and well-controlled platform offering a path to simulate the FHM. Doping the antiferromagnetic ground state of a FHM simulator at half-filling...