-
作者:Newsome, Melba
摘要:Many nations have embraced burning wood pellets to produce electricity - under the assumption that it is carbon neutral. But research shows this approach can boost greenhouse-gas emissions and threaten the health of local communities.
-
作者:Tan, Jiaxin; Xiao, Yuan; Kong, Fang; Zhang, Xiaochun; Xu, Hanwen; Zhu, Angqi; Liu, Yiming; Lei, Jianlin; Tian, Boxue; Yuan, Yafei; Yan, Chuangye
作者单位:Tsinghua University; Tsinghua University
摘要:Noradrenaline, also known as norepinephrine, has a wide range of activities and effects on most brain cell types1. Its reuptake from the synaptic cleft heavily relies on the noradrenaline transporter (NET) located in the presynaptic membrane2. Here we report the cryo-electron microscopy (cryo-EM) structures of the human NET in both its apo state and when bound to substrates or antidepressant drugs, with resolutions ranging from 2.5 & Aring; to 3.5 & Aring;. The two substrates, noradrenaline an...
-
作者:Gibney, Elizabeth
摘要:Artificial-intelligence developers are buying access to valuable data sets that contain research papers - raising uncomfortable questions about copyright.
-
作者:Lenharo, Mariana
-
作者:Madani, Navid
作者单位:Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard Medical School
摘要:In this traumatized region, exploring a rich history of scientific and medical problem-solving provides the context to imagine a better future.
-
作者:Miller, James; Hashemian, Seyed Mohammad Reza
作者单位:Shahid Beheshti University Medical Sciences
-
作者:Wong, Carissa
摘要:The threshold for survival in heat is lower than thought - researchers are using state-of-the-art climate chambers to explore when blistering conditions threaten life.
-
作者:Kim, Tae Hyun; Kang, Junwon; Jang, Haewook; Joo, Hyelyn; Lee, Gi Yoon; Kim, Hamin; Cho, Untack; Bang, Hyeeun; Jang, Jisung; Han, Sangkwon; Kim, Dong Young; Lee, Chan Mi; Kang, Chang Kyung; Choe, Pyoeng Gyun; Kim, Nam Joong; Oh, Myoung-don; Kim, Taek Soo; Kim, Inho; Park, Wan Beom; Kwon, Sunghoon
作者单位:Seoul National University (SNU); Seoul National University (SNU); Seoul National University (SNU); Seoul National University (SNU); Seoul National University (SNU); Seoul National University (SNU); Seoul National University (SNU)
摘要:Treatment assessment and patient outcome for sepsis depend predominantly on the timely administration of appropriate antibiotics1-3. However, the clinical protocols used to stratify and select patient-specific optimal therapy are extremely slow4. In particular, the major hurdle in performing rapid antimicrobial susceptibility testing (AST) remains in the lengthy blood culture procedure, which has long been considered unavoidable due to the limited number of pathogens present in the patient's b...
-
作者:Ajibade, Idowu; Shah, Sameer H.
作者单位:Emory University; University of Washington; University of Washington Seattle
摘要:Building sustainable settlements on the water is a feasible option for climate adaptation, as long as people and ecosystems are protected.
-
作者:Arab, Ali; Dadpour, Rana; Dashti, Shideh; Erfani, Encieh
作者单位:Georgetown University; James Cook University; University of Colorado System; University of Colorado Boulder; Johannes Gutenberg University of Mainz
摘要:Letter to the Editor