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作者：Wong, Kwok-Kin; Maser, Richard S.; Bachoo, Robert M.; Menon, Jayant; Carrasco, Daniel R.; Gu, Yansong; Alt, Frederick W.; Depinho, Ronald A.
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作者：Ramirez-Bravo, Osvaldo Eric
作者单位：Benemerita Universidad Autonoma de Puebla
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作者：Dolgin, Elie
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作者：Chen, Chen; Xiao, Wenya; Chen, Han Y. H.
作者单位：Lakehead University; Chinese Academy of Sciences; Institute of Botany, CAS; Jiangsu University; University of Michigan System; University of Michigan
摘要：Positive effects of plant diversity on productivity have been globally demonstrated and explained by two main effects: complementarity effects and selection effects1, 2, 3-4. However, plant diversity experiments have shown substantial variation in these effects, with driving factors poorly understood4, 5-6. On the basis of a meta-analysis of 452 experiments across the globe, we show that productivity increases on average by 15.2% from monocultures to species mixtures with an average species ri...
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作者：Huang, Huaizhi; Hu, Chunling; Na, Jie; Hart, Steven N.; Gnanaolivu, Rohan David; Abozaid, Mohamed; Rao, Tara; Tecleab, Yohannes A.; CARRIERS Consortium, Christine B.; Pesaran, Tina; Lyra, Paulo Cilas Morais; Karam, Rachid; Yadav, Siddhartha; Nathanson, Katherine L.; Domchek, Susan M.; de la Hoya, Miguel; Robson, Mark; Mehine, Miika; Bandlamudi, Chaitanya; Mandelker, Diana; Monteiro, Alvaro N. A.; Iversen, Edwin S.; Boddicker, Nicholas; Chen, Wenan; Richardson, Marcy E.; Couch, Fergus J.
作者单位：Mayo Clinic; Mayo Clinic; Mayo Clinic; Mayo Clinic; H Lee Moffitt Cancer Center & Research Institute; Mayo Clinic; University of Pennsylvania; Hospital Clinico San Carlos; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Duke University
摘要：Germline BRCA2 loss-of function variants, which can be identified through clinical genetic testing, predispose to several cancers1, 2, 3, 4-5. However, variants of uncertain significance limit the clinical utility of test results. Thus, there is a need for functional characterization and clinical classification of all BRCA2 variants to facilitate the clinical management of individuals with these variants. Here we analysed all possible single-nucleotide variants from exons 15 to 26 that encode ...
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作者：Wheeler, Michael A.; Quintana, Francisco J.
作者单位：Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Brigham & Women's Hospital; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard Medical School; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
摘要：The nervous and immune systems have complementary roles in the adaptation of organisms to environmental changes. However, the mechanisms that mediate cross-talk between the nervous and immune systems, called neuroimmune interactions, are poorly understood. In this Review, we summarize advances in the understanding of neuroimmune communication, with a principal focus on the central nervous system (CNS): its response to immune signals and the immunological consequences of CNS activity. We highli...
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作者：[Anonymous]
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作者：Wang, Bo; Che, Zhiyuan; Cheng, Cheng; Tong, Caili; Shi, Lei; Shen, Yijie; Bliokh, Konstantin Y.; Zi, Jian
作者单位：Fudan University; Henan University; Henan Academy of Sciences; Fudan University; Nanyang Technological University; Nanyang Technological University; Hiroshima University; RIKEN
摘要：Topological wave structures, such as vortices1, 2, 3, 4, 5-6, polarization textures7, 8, 9, 10-11 and skyrmions12, 13, 14, 15, 16, 17, 18-19, appear in various quantum and classical wave fields, including optics and acoustics. In particular, optical vortices have found numerous applications20,21, ranging from quantum information to astrophysics. Furthermore, both optical and acoustic structured waves are crucial in the manipulation of small particles22, 23, 24-25, from atoms to macroscopic bio...
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作者：Adli, Mazhar; Przybyla, Laralynne; Burdett, Tony; Burridge, Paul W.; Cacheiro, Pilar; Chang, Howard Y.; Engreitz, Jesse M.; Gilbert, Luke A.; Greenleaf, William J.; Hsu, Li; Huangfu, Danwei; Hung, Ling-Hong; Kundaje, Anshul; Li, Sheng; Parkinson, Helen; Qiu, Xiaojie; Robson, Paul; Schuerer, Stephan C.; Shojaie, Ali; Skarnes, William C.; Smedley, Damian; Studer, Lorenz; Sun, Wei; Vidovic, Dusica; Vierbuchen, Thomas; White, Brian S.; Yeung, Ka Yee; Yue, Feng; Zhou, Ting; MorPhiC Consortium, Neda
作者单位：Ann & Robert H. Lurie Children's Hospital of Chicago; Robert H. Lurie Comprehensive Cancer Center; Northwestern University; Feinberg School of Medicine; University of California System; University of California San Francisco; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; Northwestern University; Feinberg School of Medicine; University of London; Queen Mary University London; Stanford University; Stanford University; Stanford University; University of California System; University of California San Francisco; Fred Hutchinson Cancer Center; Memorial Sloan Kettering Cancer Center; University of Washington; University of Washington Tacoma; Stanford University; Jackson Laboratory; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; University of Miami; University of Washington; University of Washington Seattle; Ann & Robert H. Lurie Children's Hospital of Chicago; Robert H. Lurie Comprehensive Cancer Center; Northwestern University; Feinberg School of Medicine
摘要：Recent advances in functional genomics and human cellular models have substantially enhanced our understanding of the structure and regulation of the human genome. However, our grasp of the molecular functions of human genes remains incomplete and biased towards specific gene classes. The Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Consortium aims to address this gap by creating a comprehensive catalogue of the molecular and cellular phenotypes associated with null alleles of all h...
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作者：Castelvecchi, Davide
