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作者：Dax, Maximilian; Green, Stephen R.; Gair, Jonathan; Gupte, Nihar; Puerrer, Michael; Raymond, Vivien; Wildberger, Jonas; Macke, Jakob H.; Buonanno, Alessandra; Schoelkopf, Bernhard
作者单位：Max Planck Society; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Nottingham; Max Planck Society; University System of Maryland; University of Maryland College Park; University of Rhode Island; University of Rhode Island; Cardiff University; Eberhard Karls University of Tubingen
摘要：Mergers of binary neutron stars emit signals in both the gravitational-wave (GW) and electromagnetic spectra. Famously, the 2017 multi-messenger observation of GW170817 (refs. 1,2) led to scientific discoveries across cosmology3, nuclear physics4, 5-6 and gravity7. Central to these results were the sky localization and distance obtained from the GW data, which, in the case of GW170817, helped to identify the associated electromagnetic transient, AT 2017gfo (ref. 8), 11 h after the GW signal. F...
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作者：Ledford, Heidi
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作者：Gupta, Nikhil; Cheung, Henry; Payra, Syamantak; Loke, Gabriel; Li, Jenny; Zhao, Yongyi; Balachander, Latika; Son, Ella; Li, Vivian; Kravitz, Samuel; Lohawala, Sehar; Joannopoulos, John; Fink, Yoel
作者单位：Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Stanford University; Rhode Island School of Design; Brown University; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
摘要：Despite advancements in wearable technologies1,2, barriers remain in achieving distributed computation located persistently on the human body. Here a textile fibre computer that monolithically combines analogue sensing, digital memory, processing and communication in a mass of less than 5 g is presented. Enabled by a foldable interposer, the two-dimensional pad architectures of microdevices were mapped to three-dimensional cylindrical layouts conforming to fibre geometry. Through connection wi...
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作者：Gribonika, Inta; Band, Victor I.; Chi, Liang; Perez-Chaparro, Paula Juliana; Link, Verena M.; Ansaldo, Eduard; Oguz, Cihan; Bousbaine, Djenet; Fischbach, Michael A.; Belkaid, Yasmine
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作者：Nuckolls, Kevin P.; Scheer, Michael G.; Wong, Dillon; Oh, Myungchul; Lee, Ryan L.; Herzog-Arbeitman, Jonah; Watanabe, Kenji; Taniguchi, Takashi; Lian, Biao; Yazdani, Ali
作者单位：Princeton University; Princeton University; National Institute for Materials Science; National Institute for Materials Science; Massachusetts Institute of Technology (MIT); Pohang University of Science & Technology (POSTECH)
摘要：Hofstadter's butterfly, the predicted energy spectrum for non-interacting electrons confined to a two-dimensional lattice in a magnetic field, is one of the most remarkable fractal structures in nature1. At rational ratios of magnetic flux quanta per lattice unit cell, this spectrum shows self-similar distributions of energy levels that reflect its recursive construction. For most materials, Hofstadter's butterfly is predicted under experimental conditions that are unachievable using laborator...
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作者：Yeo, Megan J. R.; Zhang, Olivia; Xie, Xiaowen; Nam, Eunju; Payne, N. Connor; Gosavi, Pallavi M.; Kwok, Hui Si; Iram, Irtiza; Lee, Ceejay; Li, Jiaming; Chen, Nicholas J.; Nguyen, Khanh; Jiang, Hanjie; Wang, Zhipeng A.; Lee, Kwangwoon; Mao, Haibin; Harry, Stefan A.; Barakat, Idris A.; Takahashi, Mariko; Waterbury, Amanda L.; Barone, Marco; Mattevi, Andrea; Carr, Steven A.; Udeshi, Namrata D.; Bar-Peled, Liron; Cole, Philip A.; Mazitschek, Ralph; Liau, Brian B.; Zheng, Ning
作者单位：Harvard University; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; Howard Hughes Medical Institute; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard T.H. Chan School of Public Health; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; University of Pavia; Harvard University; Harvard Medical School; University of Miami; University of Miami
摘要：UM171 is a potent agonist of ex vivo human haematopoietic stem cell self-renewal1. By co-opting KBTBD4, a substrate receptor of the CUL3-RING E3 ubiquitin ligase (CRL3) complex, UM171 promotes the degradation of the LSD1-CoREST corepressor complex, thereby limiting haematopoietic stem cell attrition2,3. However, the direct target and mechanism of action of UM171 remain unclear. Here we show that UM171 acts as a molecular glue to induce high-affinity interactions between KBTBD4 and HDAC1/2 to p...
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作者：Guglielmi, Giorgia
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作者：Shan, Kaiyue; Lin, Yanluan; Chu, Pao-Shin; Yu, Xiping; Song, Fengfei
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作者：Chen, Sophia
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作者：Tollefson, Jeff
